Volume 10 | Issue 1

 Abstract

NAGARIKARAN: PARIBHASHA EVAN NAGARIY JIVAN KA UDAY-

Licence: creative commons attribution 4.0

  License

Creative Commons Attribution 4.0 and The Open Definition

 Keywords

NAGARIKARAN: PARIBHASHA EVAN NAGARIY JIVAN KA UDAY-

  License

Creative Commons Attribution 4.0 and The Open Definition

 Abstract

The aim of the present study is to prepare a sustained release suppository of an antihypertensive drug suitable for rectal administration. Firstly, the microspheres of metaprolol succinate were formulated using ethyl cellulose as polymer to sustain the drug release for longer time to conquer the short half life of the drug. The microspheres using ethyl cellulose were prepared by non-aqueous solvent evaporation technique. The microspheres were evaluated for micromeritic properties, particle size, percentage yield, entrapment efficiency, drug polymer compatibility, scanning electron microscopy and in-vitro drug release studies.

Licence: creative commons attribution 4.0

  License

Creative Commons Attribution 4.0 and The Open Definition

 Keywords

Polymer, Suppository, Microsphere.

  License

Creative Commons Attribution 4.0 and The Open Definition

 Abstract

Licence: creative commons attribution 4.0

  License

Creative Commons Attribution 4.0 and The Open Definition

 Keywords

Plyometric Training, Blood Pressure, Pulse Rate, Volleyball

  License

Creative Commons Attribution 4.0 and The Open Definition

 Abstract

Better Sterilization Methods overcome the problem of contamination such that we can obtain best results from plant tissue culture.

Licence: creative commons attribution 4.0

  License

Creative Commons Attribution 4.0 and The Open Definition

 Keywords

Sterilization Methods, Autoclave, Hot air oven, Filtration, Chemical agents.

  License

Creative Commons Attribution 4.0 and The Open Definition

 Abstract

Licence: creative commons attribution 4.0

  License

Creative Commons Attribution 4.0 and The Open Definition

 Keywords

Asset Management Company, Mutual Fund, Services Provided, Mean, One Way ANOVA.

  License

Creative Commons Attribution 4.0 and The Open Definition

 Abstract

Microspheres are characteristically free flowing powders consisting of proteins or synthetic polymers, which are biodegradable in nature and ideally having a particle size less than 200?m. This is the important approach in delivering therapeutic substance to the target site in sustained and controlled release fashion. Size of microspheres affects the rate of drug release. As size decreases, the surface area-to-volume ratio of the particle increases. Thus, for a given rate of drug diffusion through the microsphere, the rate of flux of drug out of the microsphere, per mass of formulation, will increase with decreasing particle size.Microspheres were prepared by optimizing various parameters and studying their effects on particle size as well as entrapment efficiency. It was then incorporated into a cream base to form a suitable topical drug delivery system. From the experiments, it was concluded that; as polymer amount increases, particle size and drug entrapment increase; as surfactant concentration increases, particle size and drug entrapment decreases; as stirring speed increases, particle size and entrapment decrease. Microspheres was prepared with aim to deliver the drug which passes through transdermal route as it provides quick onset of action when compared to oral route.

Licence: creative commons attribution 4.0

  License

Creative Commons Attribution 4.0 and The Open Definition

 Keywords

  License

Creative Commons Attribution 4.0 and The Open Definition

 Abstract

Social and realism have been quite a significant means for writers, painters, poets and artists throughout the past decades, to discuss and depict the social, political and economic situations in their countries through their works. Further explained, the term refers to the social reality of society as the word 'social' refers to people who are part of a particular society, and the term 'realism' refers to the way these people are represented in works of Art or Literature. Writers usually represent the struggle of the common working class in distinction with the upper class through fiction. One such important writer is Pramoedya Ananta Toer, an Indonesian writer, whose works are translated into English and many other languages. Toer's works are mostly banned in Indonesia because of his opposition to tyranny and injustice in his country. His works mostly depict the unfairness and glory of human life through autobiographical elements in his novels. The Girl from The Coast is a novel based on the true story of his grandmother's marriage and life as a poor fisherman's child entering the world of noblemen and the upper class only to be used as a worthless concubine. This paper is an analysis of the novel by Toer, illustrating the past Feudalist society of Java and the status of women in a Muslim Aristocratic society, where unjust treatment is the only thing a woman ascending from a poor village can own, while the privilege is given to the nobles in the community. The paper also represents social differences of class applying Marxism theory.

Licence: creative commons attribution 4.0

  License

Creative Commons Attribution 4.0 and The Open Definition

 Keywords

Social, realism, economic situations, common working class, Feudalist society, unjust treatment, Marxism.

  License

Creative Commons Attribution 4.0 and The Open Definition

 Abstract

In this paper we systematize the knowledge on several cybersecurity use cases. We commence with a historical prelude, having in mind to identify military-relevant use cases. We continue with a review of several known and publicly disclosed cybersecurity techniques. Specifically, we go over classical defense options against distributed denial of service attacks and cover anonymization schemes. Perhaps more importantly, we consider their applications in the field of cyberdefense as well as cyberwarfare.

Licence: creative commons attribution 4.0

  License

Creative Commons Attribution 4.0 and The Open Definition

 Keywords

cybersecurity, cyberdefense, cyberwarfare.

  License

Creative Commons Attribution 4.0 and The Open Definition

 Abstract

Licence: creative commons attribution 4.0

  License

Creative Commons Attribution 4.0 and The Open Definition

 Keywords

Various techniques, general method, proposed work, layout of approach

  License

Creative Commons Attribution 4.0 and The Open Definition

 Abstract

Coronavirus disease caused by the infamous severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was first discovered in Wuhan, China in December 2019 and later, spreading to all parts of the world resulting in a Pandemic. The outbreak of Coronavirus has impacted every segment of life such as education, economy and health etc. The outbreak has reported the psychological impact of the quarantine and lockdown on human health. The study aims to explore the effect of anxiety, stress and psychological distress on health-related quality of life. 50 subjects were taken for the study out of which 22 were males and 28 were females. Four scales were taken for the study which are Hamilton Anxiety Rating Scale, Perceived Stress Scale, Impact of Event Scale-R and SF-36 Questionnaire. They were interviewed using these four scales and correlation was interpreted using Pearson correlation test. It was found that the scales for anxiety, stress and psychological distress are negatively correlated with the components of SF-36 questionnaire. Hence, concluding that as anxiety, stress and psychological distress increases, quality of life decreases.

Licence: creative commons attribution 4.0

  License

Creative Commons Attribution 4.0 and The Open Definition

 Keywords

COVID-19, Lockdown, quarantine, Health-related Quality of life, Anxiety, stress and psychological distress.

  License

Creative Commons Attribution 4.0 and The Open Definition

 Abstract

This paper focus on development of maximum power generation from the wind energy system. Recently, Maximum Power Point Tracking (MPPT) algorithms play an important role in optimizing the output obtained from the wind energy system. It is well known that wind speed varies; the power from the wind turbine changes accordingly. So, implementation of MPPT is necessary to keep output power at its maximum value with sudden change in either wind speed or load. The same dc energy will be fed to load with inverter and catch required load demand. PI controller-based inverter system is used to improve the power the power of wind energy system. The model considers the MPPT technique in order to extracting maximum possible power form the wind energy system based on permeant magnet synchronous generator (PMSG).

Licence: creative commons attribution 4.0

  License

Creative Commons Attribution 4.0 and The Open Definition

 Keywords

Permeant Magnet Synchronous Generator (PMSG), Boost converter, three phase inverter, wind energy conversion system.

  License

Creative Commons Attribution 4.0 and The Open Definition

 Abstract

International and national crises often highlight inequalities in the labour market that disproportionately affect individual from diverse background. We need to build a disability inclusive response to covid-19. Since the beginning of the year more than 200 nations across the globe have been affected by covid-19. Many are still reeling under the devastating affects of the pandemic, with both public health and economy emerging market seem to especially vulnerable. In several of the Indian states we hear community members and associate narrate stories how migrant workers, Safai karamchari, Sanitation workers are badly affected due to covid-19 pandemic. While all of us at home maintain physical distance, they are forced to continue to serve us clean our surroundings to keep us safe. When the news of covid-19 broke, everyone wanted to stay indoors protect themselves and create a cocoon but, while the rich and the elite are doing this, the poor still come to pick up the garbage, still clean the roads, and still continue to deliver essential goods. This is happening at a risk that they have taken either due to perhaps their lack of awareness or lack of knowledge are for the mere need to survive, whatever may be the reason but only the disadvantage section of the society are suffered. Despite government having taken drastic step including offering varying degree of support to their citizens, there are some sections of the society that have been inadvantly excluded like person with disabilities ( PWDs ) more than 1 billion in number globally are one such person. This is because much of the advocacy on how to save during the pandemic.

Licence: creative commons attribution 4.0

  License

Creative Commons Attribution 4.0 and The Open Definition

 Keywords

Elite Section,disadvantaged Sections, youth Sections

  License

Creative Commons Attribution 4.0 and The Open Definition

 Abstract

Elbasvir/Grazoprevir (Zepatier) is a combination product with an FDA-approved indication for the treatment of chronic HCV genotypes (GTs)1and 4 in adults.Elbasvir is an NSSA inhibitor, preventing hepatitis C viral RNA replication and vision assembly.Median EC50 values range from 0.2 to 3600 pmol/L,based on genotype. Grazoprevir is a protease inhibitor of HCV NS3/4A that prevents cleavage of the polyprotein necnecessary for replication. Median EC50 values range from 0.16 to 0.8pmol/L.Analytical method play an important role in the physicochemical properties description. This review includes most recent analytical methods such as various spectroscopic methods (Simultaneous estimation, Mass Spectroscopy)and chromatographic methods (RP-HPLC, stability indicating HPLC )for determination of Elbasvir and Grazoprevir in various pharmaceutical dosage forms and biological fluid matrix were reported.

Licence: creative commons attribution 4.0

  License

Creative Commons Attribution 4.0 and The Open Definition

 Keywords

Elbasvir,Grazoprevir, RP-HPLC, UV-Visible spectroscopy, Synchronous Fluorescence spectroscopy

  License

Creative Commons Attribution 4.0 and The Open Definition

 Abstract

Licence: creative commons attribution 4.0

  License

Creative Commons Attribution 4.0 and The Open Definition

 Keywords

Keywords - Spirituality, Meditation, self-introspection, self- development, liberation.

  License

Creative Commons Attribution 4.0 and The Open Definition

 Abstract

Abstract: Analytical method development and validation plays an important role in the discovery, development and manufacture of pharmaceuticals. These methods used to ensure the identity, purity, potency and performance of drug products. In the present study, a successful attempt was made for the HPLC quantitative estimation of Diloxanide furoate in bulk formulation. The method was developed by experimentation based on thorough literature survey and ascertained by statistical parameters of sampling. The entire work was performed on waters HPLC with U.V. Vis detector. The result obtained shows the developed method to be precise, simple, rapid and accurate. Thus these can be used for routine analysis of Diloxanide furoate in bulk drug dosage form. It was thus, concluded that the proposed method is new, simple, accurate, safe, free form pollution, precise and can be successfully employed in the routine analysis. The simplicity, rapidity reproducibility and economy of the proposed methods completely fulfill the objective of this research work.

Licence: creative commons attribution 4.0

  License

Creative Commons Attribution 4.0 and The Open Definition

 Keywords

Keyword: Diloxanide furonate, HPLC Method validation, Method development, Stability study

  License

Creative Commons Attribution 4.0 and The Open Definition

 Abstract

By the year 2050 the world population will increase from 7.9 billion to 9.7 billion and close to 66% of this population will live in cities, declaring the age of the vertical city. High rise development offsets rising land costs and absorbs demand for space. However there are many problems associated with high rise living, risks associated with urbanization like disease, crime, environmental damage and vulnerability to disasters and social conflict also compound as density increases. This research aims at addressing these problems in order to create better spaces and places to live. The problems addressed include, issue of cost- affordability, inclusivity of community, multiplying ground level- creating neighborhood spaces, adaptive and flexible interior design and scope for incremental development.

Licence: creative commons attribution 4.0

  License

Creative Commons Attribution 4.0 and The Open Definition

 Keywords

Adaptive and Flexible Interior Design, Affordability, Inclusivity of Community. Incremental Development, Multiplication of Ground Level, Neighborhood Spaces, Sustainability.

  License

Creative Commons Attribution 4.0 and The Open Definition

 Abstract

Herbal based hair dyes are being preferred on large scale; due to the vast number of advantages it exerts to overcome the ill-effects of a chemical based hair dye. We have attempted to prepare and standardize this preparation to ensure its quality as well as stability aspects. Objective: The current research was aimed at the preparation of herbal hair dye and the evaluation of its various parameters as Organoleptic, physico-chemical, phytoconstituents, rheological aspects, patch test and stability testing for its efficacy and shelf life.

Licence: creative commons attribution 4.0

  License

Creative Commons Attribution 4.0 and The Open Definition

 Keywords

Herbal hair dye, Patch test, Organoleptic, Physico- chemical evaluation, Herbal drugs and Chemical hair dye.

  License

Creative Commons Attribution 4.0 and The Open Definition

 Abstract

Licence: creative commons attribution 4.0

  License

Creative Commons Attribution 4.0 and The Open Definition

 Keywords

Keywords: Biodegradation, Benzonitrilase, Bacteria, Bacillus, Purification.

  License

Creative Commons Attribution 4.0 and The Open Definition

 Abstract

Licence: creative commons attribution 4.0

  License

Creative Commons Attribution 4.0 and The Open Definition

 Keywords

LDL-Low density,VLDL-very low density,HDL-high density lipoprotein,TGL-Triglyceride level,DQOL-Diabetes quality of life.

  License

Creative Commons Attribution 4.0 and The Open Definition

 Abstract

Abstract: Background: Overweight and obesity are defined as abnormal or excessive fat accumulation that may impair health. More than 100 million individuals are obese in India and the prevalence of obesity varies from 10% to 50%, there is an increase in obesity among young adults, mainly college students. Materials and Method: This study is an experimental study performed on 30 female college students of B.N. Patel College of physiotherapy. Sampling was done using a convenient sampling method. The Assessment tool used to record VO2 max was the queen's step test. The experimental group was given 6 weeks of Resistance exercise training, and the Traditional group was given 6 weeks of traditional exercise, both groups have followed 45 minutes for a session for 4 days a week. Results were analyzed using SPSS software and unpaired and paired t-test. Conclusion: we have found that there was a significant increase in VO2max after 6 weeks of Resistance exercise training and Traditional exercise training. Resistance exercise training is more effective than traditional exercise training. Having relevant long-duration resistance exercise training is recommended to all overweight college females to improve cardiovascular fitness and prevent future cardiovascular risk.

Licence: creative commons attribution 4.0

  License

Creative Commons Attribution 4.0 and The Open Definition

 Keywords

Keywords: Maximum Oxygen Uptake (VO2max), Body Mass Index (BMI)

  License

Creative Commons Attribution 4.0 and The Open Definition