Volume 9 | Issue 11 |

 Abstract

????? ???? ????? ?? ???? ???? ??? ????? ?? ????????? ??? ?? ?????? ?? ?????? ?? ??? ???? ?? ????? ?? ????? ??? ????????? ???? ?? ????? ????? ?????????? ?? ?????? ???? ???? ??? ??? ???? ??????? ????? ?? ???? ??? ??? ?????? ???? ??? ???? ??? ????????? ?? ????? ?? ?????? ??????? ?? ?? ????? ???? ?? ?? ?? ?????????? ???? ??????? ?? ?????? ???? ?? ?? ?? ???? ????? ?? ????? ????? ???? ??? ???????? ?? ??????? ???? ?? ??? ? ???? ?????? ???? ???? ?? ???? ???? ????? ?? ?? ?????? ??? ???? ??? ????? ??????? ?? ?? ???? ??????? ?? ????????? ?? ???????? ?? ?????? ?? ????? ????? ?? ?????? ?? ???? ??? ??? ???? ??????? ?? ?????? ??? ????? ?? ??? ?? ???? ??? ???? ??? ???-??? ?? ????? ?? ????? ?? ??????? ???? ?????

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???? ???, ????? ???????, ???? ?????, ?????

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ABSTRACT: A simple, sensitive and high performance liquid chromatographic method was developed for the estimation of anti-diabetic drugs Metformin Hydrochloride (MET) and Teneligliptin (TEN) in pure and in pharmaceutical dosage forms. A Gemini C18 column (150x4.6mm, 5?) was used with a mobile phase contain a mixture of Ammonium Acetate Buffer (pH-3) and Acetonitrile taking ratio of 42: 58. Set the flow rate was 0.3ml/min and effluents were monitored at 255nm and eluted at 5.18min (MET) and 8.1min (TEN). Calibration curve was plotted within range from 0.5-51 ?g/ml for MET and 0.3-31 ?g/ml for TEN. This assay was validated for the parameters i.e. accuracy, precision, robustness and all system suitability parameter. The method can be useful routine analysis for the determination on metformin and teneligliptin in pharmaceutical dosage forms.

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KEYWORDS: - Metformin hydrochloride, Teneligliptin, HPLC, Pharmaceutical dosage forms.

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The knowledge of the inter-relationship between periodontal tissues and restoration is a predominant to ensure relevant form, function, esthetics and comfort of the dentition. Most of us as a dentist are ignorant of this important relationship, hence uncertainty remains regarding a special concept that is biologic width, its maintenance and applications of crown lengthening in cases of biologic width violation. A Crown lengthening procedure is a constitutive component of the esthetic armamentarium and is utilized with increasing frequency to inflate the appearance and retention of restorations placed within the esthetic zone. Thus, we are presenting a case report on management of biological width with gingivo-osseous surgery.

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biological width, crown lengthening, periodontal health, anterior restoration, esthetic restoration

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Background: Thyroid cancer is the most common endocrine cancer with an increasing incidence in the world. Immunohistochemistry is widely used to differentiate benign and malignant lesions in thyroid cancer through the identification of molecular markers. In this study, we aimed to examine the association between matrix metalloproteinase-9 (MMP-9) expression and its relationship with the clinical stage of PTC patients. Methods: We recruited 26 patients with PTC in Dr. Soetomo General Hospital (Surabaya, Indonesia) in between September 2020-Agustus 2021. MMP-9 expression was examined using immunohistochemistry. Clinical staging was determined using 8th American Joint Committee on Cancer (AJCC) guideline. Results: The number of females was higher than males (73.1% and 26.9%, respectively). There was no significant association between clinical stage and MMP-9 expression (P = 0.16). The results of the analysis also showed that there were no statistically significant association between T, N, and M with MMP-9 expression (P > 0.05 for all). Conclusion: There was no significant association between MMP-9 expression and clinical staging of papillary thyroid carcinoma. Keyword: Matrix metalloproteinase-9, clinical staging, papillary thyroid carcinoma, TNM system

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Matrix metalloproteinase-9, clinical staging, papillary thyroid carcinoma, TNM system

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Imagination is the only thing where you can wander without limitations. It is a pleasure which can be tasted by every individual. A poor man in China can visit Disney land in America through his imagination. It makes impossible things possible. S.T. Coleridge is the poet who is well known for his imagery. Kubla khan is one of his famous poem where he poured his imagination of thoughts in words. Coleridge makes his reader to smell the entire fragrance of imagination through his poem. This is the poem of his dream and it has abrupt ending. This poem happens in the place called Xanadu which was ruled by a Mangolian emperor Kubla Khan. He orders his servants to build a massive dome building and the poem continues with lots of beautiful sceneries.

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Imagination, Hermeneutics, Reader's response theory

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Newborn resuscitation is a complex procedure that requires the use of specialized knowledge and skills in an emotionally charged and stressful situation. Knowledge about newborn resuscitation, frequent performance of skills and comfort level with skill performance is dimensions of quality implementation of newborn resuscitation. Newborn resuscitation is a series of action that are taken in order to revive an infant immediately after birth so that normal respiration and circulation may be initiated and maintained. It is an attempt to facilitate the dynamic transition from fetal to neonatal physiology. The approach used for this study was non experimental study research approach. The research variable of the study is knowledge and practice regarding resuscitation of Newborn among staff nurses working in neonatal intensive care unit and extraneous variable are age, gender education qualification, area of residence, marital status, professional experience and source of information. The pilot study was conducted to find the feasibility of the study 23nd of February 2021 to 28th of February 2021 among Staff nurses. The main study was conducted from 21-04- 2021 to 30-04-2021 among 60 subjects; the subject was selected by convenient sampling technique and data was analysed and interpreted using descriptive and inferential statistics. The overall knowledge on resuscitation of Newborn. The mean score is 19.16 with a mean percentage of 59.87 with a standard deviation of 1.719, practice scores of staff nurses on resuscitation of Newborn were found to be 73.7% with standard deviation 1.91. The present study was to assess the knowledge and practice regarding resuscitation of Newborn among staff nurses working in neonatal intensive care unit had moderate knowledge and moderately Good Practice on resuscitation of Newborn.

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knowledge and practice, resuscitation, newborn

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, Entertainment , Indian Cinema Bio-Pic, Enlightenment

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A STUDY TO ASSESS THE KNOWLEDGE REGARDING HYSTERECTOMY AMONG WOMEN ATTENDING MCH CENTER, AT TIRUPATI. Objectives: ? To assess the level of knowledge among women regarding hysterectomy. ? To find out the association between knowledge scores of women regarding hysterectomy with their selected socio-demographic variables. Methodology: The research approach used for the present study was Cross-Sectional Descriptive Research Design. The sample of the study were chosen by Non-Probability Convenient Sampling Technique, which includes 100 Women aged between 35-60 years who were attending MCH center at Tirupati. A structured questionnaire was used to collect the data which consists of 25 dichotomous questions. Results: The study findings revealed that, 61% had moderate knowledge, 23% had adequate knowledge and 16% had inadequate knowledge and a significant association between age of women (x2= 38.311, P=0.001), marital status (x2=18.449, P=0.001), education of the women (x2 =26.400, P=0.001), occupation (x2= 21.019, P=0.002) living area (x2= 20.572, P=0.002), type of family (x2=13.798,P=0.008), family history of hysterectomy(x2=9.509,P=0.009), were significant at p <0.01 level. The relationship between family income of the women (x2=10.041, P=0.040), was significant at <0.05 level. Conclusion: The conclusion suggests that, majority of women had moderate knowledge on hysterectomy and hence women need to improve the knowledge regarding hysterectomy.

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Knowledge, Hysterectomy.

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Oral health, dental attrition, tooth wear, public health

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