Journal IJCRT UGC-CARE, UGCCARE( ISSN: 2320-2882 ) | UGC Approved Journal | UGC Journal | UGC CARE Journal | UGC-CARE list, New UGC-CARE Reference List, UGC CARE Journals, International Peer Reviewed Journal and Refereed Journal, ugc approved journal, UGC CARE, UGC CARE list, UGC CARE list of Journal, UGCCARE, care journal list, UGC-CARE list, New UGC-CARE Reference List, New ugc care journal list, Research Journal, Research Journal Publication, Research Paper, Low cost research journal, Free of cost paper publication in Research Journal, High impact factor journal, Journal, Research paper journal, UGC CARE journal, UGC CARE Journals, ugc care list of journal, ugc approved list, ugc approved list of journal, Follow ugc approved journal, UGC CARE Journal, ugc approved list of journal, ugc care journal, UGC CARE list, UGC-CARE, care journal, UGC-CARE list, Journal publication, ISSN approved, Research journal, research paper, research paper publication, research journal publication, high impact factor, free publication, index journal, publish paper, publish Research paper, low cost publication, ugc approved journal, UGC CARE, ugc approved list of journal, ugc care journal, UGC CARE list, UGCCARE, care journal, UGC-CARE list, New UGC-CARE Reference List, UGC CARE Journals, ugc care list of journal, ugc care list 2020, ugc care approved journal, ugc care list 2020, new ugc approved journal in 2020, ugc care list 2021, ugc approved journal in 2021, Scopus, web of Science.
How start New Journal & software Book & Thesis Publications
Submit Your Paper
Login to Author Home
Communication Guidelines

WhatsApp Contact
Click Here

  IJCRT Search Xplore - Search all paper by Paper Name , Author Name, and Title

Volume 13 | Issue 9 |

Volume 13 | Issue 9 | Month  
Downlaod After Publication
1) Table of content index in PDF
2) Table of content index in HTML 2)Table of content index in HTML
3) Front Page                     3) Front Page
4) Back Page                     4) Back Page
5) Editor Board Member 5)Editor Board Member
6) OLD Style Issue 6)OLD Style Issue
Chania Chania
IJCRT Journal front page IJCRT Journal Back Page

  Paper Title: A Study on Bacteriological water analysis ofRishikund, SitakundandRajgir hot spring sites of Bihar, India

  Author Name(s): Dr. Baliram Pd. Singh, Dr. Prasoon Prakash

  Published Paper ID: - IJCRT2509099

  Register Paper ID - 293370

  Publisher Journal Name: IJPUBLICATION, IJCRT

  DOI Member ID: 10.6084/m9.doi.one.IJCRT2509099 and DOI : https://doi.org/10.56975/ijcrt.v13i9.293370

  Author Country : Indian Author, India, 812007 , Bhagalpur, 812007 , | Research Area: Chemistry All

Published Paper URL: http://ijcrt.org/viewfull.php?&p_id=IJCRT2509099
Published Paper PDF: download.php?file=IJCRT2509099
Published Paper PDF: http://www.ijcrt.org/papers/IJCRT2509099.pdf

  Your Paper Publication Details:

  Title: A STUDY ON BACTERIOLOGICAL WATER ANALYSIS OFRISHIKUND, SITAKUNDANDRAJGIR HOT SPRING SITES OF BIHAR, INDIA

 DOI (Digital Object Identifier) : https://doi.org/10.56975/ijcrt.v13i9.293370

 Pubished in Volume: 13  | Issue: 9  | Year: September 2025

 Publisher Name : IJCRT | www.ijcrt.org | ISSN : 2320-2882

 Subject Area: Chemistry All

 Author type: Indian Author

 Pubished in Volume: 13

 Issue: 9

 Pages: a811-a817

 Year: September 2025

 Downloads: 70

  E-ISSN Number: 2320-2882

 Abstract

Sitakund, Rishikund and Rajgir hot spring site is a sulphur containing hot spring site. Bacteriological water analysis is a method of analyzing water to estimate the numbers of bacteria present. It is a micro biological analytical procedure which uses sample of water and form these samples determine the concentration of bacteria. The Biological parameters were analyzed as per WHO, APHA. The bacteriological parameter included SPC (standard plate count), MPN (most probable number). Bacterial contamination of drinking water sources is the most common health risk. The water sample were collected from three selected hot spring site Rishikund, Sitakund&Rajgir during period (October 2014 to June 2016) within and interval of four month. All the results were compared with WHO, APHA, BIS and found that water is potable.


Licence: creative commons attribution 4.0

  License

Creative Commons Attribution 4.0 and The Open Definition

 Keywords

APHA, BIS, WHO, SPC, MPN

  License

Creative Commons Attribution 4.0 and The Open Definition


  Paper Title: Asphalt Flexible Pavements With The Utilization Of Scrap Plastic And Crumble Tyre Rubber

  Author Name(s): BHAWNA GUNDAL, R.S.KESHARWANI

  Published Paper ID: - IJCRT2509098

  Register Paper ID - 293421

  Publisher Journal Name: IJPUBLICATION, IJCRT

  DOI Member ID: 10.6084/m9.doi.one.IJCRT2509098 and DOI :

  Author Country : Indian Author, India, 124001 , ROHTAK, 124001 , | Research Area: Science and Technology

Published Paper URL: http://ijcrt.org/viewfull.php?&p_id=IJCRT2509098
Published Paper PDF: download.php?file=IJCRT2509098
Published Paper PDF: http://www.ijcrt.org/papers/IJCRT2509098.pdf

  Your Paper Publication Details:

  Title: ASPHALT FLEXIBLE PAVEMENTS WITH THE UTILIZATION OF SCRAP PLASTIC AND CRUMBLE TYRE RUBBER

 DOI (Digital Object Identifier) :

 Pubished in Volume: 13  | Issue: 9  | Year: September 2025

 Publisher Name : IJCRT | www.ijcrt.org | ISSN : 2320-2882

 Subject Area: Science and Technology

 Author type: Indian Author

 Pubished in Volume: 13

 Issue: 9

 Pages: a804-a810

 Year: September 2025

 Downloads: 47

  E-ISSN Number: 2320-2882

 Abstract

Unexpected pavement breakdown issues, such as potholes, unevenness, cracks, etc., have been reported by a number of road agencies. This results in a poor understanding of roads and their lifespan. Conversely, rubbers, polymers, and other materials are being added daily. Waste materials such as plastic bottles, polymers, mugs, and used tires can be recycled by grinding them up or mixing them with cementers. They can also be used to cover asphalt and bitumen using any heating method.In this work, we employed crumbed rubber and plastic as binding agents in relation to bitumen and total. We employ bitumen, strength, and total (of various colored sizes) as accessories on bituminous roads. This study includes vivid tests on bitumen penetrate value, stiffness, and softening point in addition to summations like crushing value, impacting value, bruising value, and particular graveness. This paper uses a lot of sequences.Sustainability is a pressing requirement in the construction sector globally, and in order to lessen the impact on the natural environment, the usage of waste materials in road building is being reduced. To establish their suitability for the design, building, and preservation of the pavements, several apparent accessories and technologies have been built into the trace structure.Among them are rubber and polymers. Due to modifications to lifestyle and growing populations, the amount of plastic garbage in external solid waste is increasing. Additionally, the majority of tires, particularly those found on motor vehicles, are made of synthetic rubber. Getting rid of both is a major issue.At the exact same time, the constant rise in automobile traffic highlights the need for greater engineering and road condition. The desired mechanical properties for a certain road mixture can be improved by partially substituting the traditional material with this waste polymer and rubber.


Licence: creative commons attribution 4.0

  License

Creative Commons Attribution 4.0 and The Open Definition

 Keywords

Plastic, Rubber, Pavement, Bitumen

  License

Creative Commons Attribution 4.0 and The Open Definition


  Paper Title: SKILL-BASED PREPARATION OF AYURVEDIC VALUE-ADDED PRODUCTS IN COLLEGE LABORATORY: AN NEP 2020 PERSPECTIVE

  Author Name(s): Dr.Savita Anand Gaikwad

  Published Paper ID: - IJCRT2509097

  Register Paper ID - 293445

  Publisher Journal Name: IJPUBLICATION, IJCRT

  DOI Member ID: 10.6084/m9.doi.one.IJCRT2509097 and DOI :

  Author Country : Indian Author, India, 412206 , Pune, 412206 , | Research Area: Life Sciences All

Published Paper URL: http://ijcrt.org/viewfull.php?&p_id=IJCRT2509097
Published Paper PDF: download.php?file=IJCRT2509097
Published Paper PDF: http://www.ijcrt.org/papers/IJCRT2509097.pdf

  Your Paper Publication Details:

  Title: SKILL-BASED PREPARATION OF AYURVEDIC VALUE-ADDED PRODUCTS IN COLLEGE LABORATORY: AN NEP 2020 PERSPECTIVE

 DOI (Digital Object Identifier) :

 Pubished in Volume: 13  | Issue: 9  | Year: September 2025

 Publisher Name : IJCRT | www.ijcrt.org | ISSN : 2320-2882

 Subject Area: Life Sciences All

 Author type: Indian Author

 Pubished in Volume: 13

 Issue: 9

 Pages: a799-a803

 Year: September 2025

 Downloads: 43

  E-ISSN Number: 2320-2882

 Abstract

Ayurveda, the ancient Indian system of medicine, emphasizes preventive healthcare and the therapeutic use of natural resources. Value-added Ayurvedic products such as Amla sharbat, Amla syrup, Amla candy, Ale pak, Green chilli pickle, Amla supari, and Mixed fruit jam were prepared in the college laboratory by undergraduate students under faculty supervision. The study followed a hands-on, skill-oriented methodology including selection of raw materials, extraction, cooking, preservation, drying, packaging, and storage. Organoleptic and stability evaluations revealed that the products were acceptable in quality, with Amla-based preparations retaining significant nutritional value, especially Vitamin C.??The initiative not only demonstrated the medicinal and nutritional potential of traditional Ayurvedic products but also served as a practical educational model in alignment with NEP 2020. Students developed skills in product formulation, quality assessment, hygiene, and entrepreneurship while integrating with botany knowledge. This approach highlights the importance of experiential learning in higher education, promoting self-reliance, entrepreneurship, and preservation of traditional knowledge.?


Licence: creative commons attribution 4.0

  License

Creative Commons Attribution 4.0 and The Open Definition

 Keywords

Ayurveda, Amla, Value-added products, NEP 2020, Experiential learning, Skill development

  License

Creative Commons Attribution 4.0 and The Open Definition


  Paper Title: SURVEILLANCE DRONE WITH LANDMINE DETECTION AND ROBOTIC ARM

  Author Name(s): Mr. Prasad Bhaginath Khaire, Ms. Samruddhi Santosh Khairnar, Mr. Kunal Shivaji Khangal, Ms. Dhanashri Dipak Bhamare, Mrs. L. S. Bairagi

  Published Paper ID: - IJCRT2509096

  Register Paper ID - 293435

  Publisher Journal Name: IJPUBLICATION, IJCRT

  DOI Member ID: 10.6084/m9.doi.one.IJCRT2509096 and DOI :

  Author Country : Indian Author, India, 423101 , Chandwad, 423101 , | Research Area: Science and Technology

Published Paper URL: http://ijcrt.org/viewfull.php?&p_id=IJCRT2509096
Published Paper PDF: download.php?file=IJCRT2509096
Published Paper PDF: http://www.ijcrt.org/papers/IJCRT2509096.pdf

  Your Paper Publication Details:

  Title: SURVEILLANCE DRONE WITH LANDMINE DETECTION AND ROBOTIC ARM

 DOI (Digital Object Identifier) :

 Pubished in Volume: 13  | Issue: 9  | Year: September 2025

 Publisher Name : IJCRT | www.ijcrt.org | ISSN : 2320-2882

 Subject Area: Science and Technology

 Author type: Indian Author

 Pubished in Volume: 13

 Issue: 9

 Pages: a791-a798

 Year: September 2025

 Downloads: 55

  E-ISSN Number: 2320-2882

 Abstract

Unmanned Aerial Vehicles (UAVs) have gained significant importance in defence, disaster management, and security applications due to their versatility and ability to operate in hazardous environments. This research presents the design and development of a multifunctional surveillance drone integrated with landmine detection capabilities and a robotic arm for remote handling tasks. The system is intended to enhance safety for military personnel by reducing direct human exposure to life-threatening conditions. This project is about a special drone that can move both in the air and on the ground as it work like rover. The proposed drone is built on a quadcopter platform equipped with gear motor and wheels to work like rover, a high-resolution camera for real-time aerial surveillance. For landmine detection, the system uses a metal detection module, enabling the identification of explosive threats from a safe distance. A robotic arm mounted on the drone provides additional functionality, allowing for object manipulation such as picking up suspicious materials, collecting samples. The drone is remotely operated through a wireless communication link, with an onboard flight controller managing navigation. The project demonstrates a hybrid approach that combines aerial mobility with ground-focused sensing, offering a cost-effective and scalable solution for security forces. Field testing showed promising results in detecting metallic landmine simulants, maintaining flight stability during arm operation, and providing continuous live feed for surveillance. This work contributes to the growing field of UAV-based defence applications by proposing a multipurpose platform that improves operational safety, and supports in reducing demining human efforts. Future developments will focus on improving detection accuracy and extending flight endurance.


Licence: creative commons attribution 4.0

  License

Creative Commons Attribution 4.0 and The Open Definition

 Keywords

Aerial Surveillance, Ground Surveillance, Operational safety, Landmine detection, Material manipulation, GPS Tracking, Wireless Telemetry

  License

Creative Commons Attribution 4.0 and The Open Definition


  Paper Title: Role of Women in Premchand's Novels: A Socio-Cultural Perspective

  Author Name(s): Sonam Singh, Dr. Jaysingh Yadav

  Published Paper ID: - IJCRT2509095

  Register Paper ID - 275564

  Publisher Journal Name: IJPUBLICATION, IJCRT

  DOI Member ID: 10.6084/m9.doi.one.IJCRT2509095 and DOI :

  Author Country : Indian Author, India, 226002 , Lucknow, 226002 , | Research Area: Arts All

Published Paper URL: http://ijcrt.org/viewfull.php?&p_id=IJCRT2509095
Published Paper PDF: download.php?file=IJCRT2509095
Published Paper PDF: http://www.ijcrt.org/papers/IJCRT2509095.pdf

  Your Paper Publication Details:

  Title: ROLE OF WOMEN IN PREMCHAND'S NOVELS: A SOCIO-CULTURAL PERSPECTIVE

 DOI (Digital Object Identifier) :

 Pubished in Volume: 13  | Issue: 9  | Year: September 2025

 Publisher Name : IJCRT | www.ijcrt.org | ISSN : 2320-2882

 Subject Area: Arts All

 Author type: Indian Author

 Pubished in Volume: 13

 Issue: 9

 Pages: a782-a790

 Year: September 2025

 Downloads: 171

  E-ISSN Number: 2320-2882

 Abstract

Role of Women in Premchand's Novels: A Socio-Cultural Perspective


Licence: creative commons attribution 4.0

  License

Creative Commons Attribution 4.0 and The Open Definition

 Keywords

Role of Women in Premchand's Novels: A Socio-Cultural Perspective

  License

Creative Commons Attribution 4.0 and The Open Definition


  Paper Title: Nanotechnology in Cancer Drug Delivery: A Revolutionary Approach to Targeted Therapy

  Author Name(s): Pratik.A.Ugare, Snehal.M.Jadhav, Sanskruti.S.Desai

  Published Paper ID: - IJCRT2509094

  Register Paper ID - 286381

  Publisher Journal Name: IJPUBLICATION, IJCRT

  DOI Member ID: 10.6084/m9.doi.one.IJCRT2509094 and DOI :

  Author Country : Indian Author, India, 416101 , Jaysingpur, 416101 , | Research Area: Pharmacy All

Published Paper URL: http://ijcrt.org/viewfull.php?&p_id=IJCRT2509094
Published Paper PDF: download.php?file=IJCRT2509094
Published Paper PDF: http://www.ijcrt.org/papers/IJCRT2509094.pdf

  Your Paper Publication Details:

  Title: NANOTECHNOLOGY IN CANCER DRUG DELIVERY: A REVOLUTIONARY APPROACH TO TARGETED THERAPY

 DOI (Digital Object Identifier) :

 Pubished in Volume: 13  | Issue: 9  | Year: September 2025

 Publisher Name : IJCRT | www.ijcrt.org | ISSN : 2320-2882

 Subject Area: Pharmacy All

 Author type: Indian Author

 Pubished in Volume: 13

 Issue: 9

 Pages: a778-a781

 Year: September 2025

 Downloads: 127

  E-ISSN Number: 2320-2882

 Abstract

Nanotechnology has introduced groundbreaking advancements in oncology by revolutionizing how anticancer agents are delivered. Conventional chemotherapy faces challenges like poor selectivity and severe systemic toxicity. Nanocarrier-based drug delivery systems--including liposomes, dendrimers, polymeric particles, micelles, and metallic nanoparticles--enable site-specific drug accumulation, enhance bioavailability, and minimize adverse effects. This review comprehensively examines key nanotechnology principles in cancer treatment, types of Nano systems, FDA-approved nano formulations, and emerging innovations, underscoring their transformative role in targeted cancer therapy.


Licence: creative commons attribution 4.0

  License

Creative Commons Attribution 4.0 and The Open Definition

 Keywords

Cancer therapy, Nanotechnology, Nanocarriers, Targeted drug delivery, Liposomes, Chemotherapy, Oncology

  License

Creative Commons Attribution 4.0 and The Open Definition


  Paper Title: Dreams That Fade, Hope That Remains: Always Remember That Your Superpower Lies in Being a Girl

  Author Name(s): Tahir Metkari

  Published Paper ID: - IJCRT2509093

  Register Paper ID - 293461

  Publisher Journal Name: IJPUBLICATION, IJCRT

  DOI Member ID: 10.6084/m9.doi.one.IJCRT2509093 and DOI :

  Author Country : Indian Author, India, 415523 , Phaltan (Satara), 415523 , | Research Area: Social Science All

Published Paper URL: http://ijcrt.org/viewfull.php?&p_id=IJCRT2509093
Published Paper PDF: download.php?file=IJCRT2509093
Published Paper PDF: http://www.ijcrt.org/papers/IJCRT2509093.pdf

  Your Paper Publication Details:

  Title: DREAMS THAT FADE, HOPE THAT REMAINS: ALWAYS REMEMBER THAT YOUR SUPERPOWER LIES IN BEING A GIRL

 DOI (Digital Object Identifier) :

 Pubished in Volume: 13  | Issue: 9  | Year: September 2025

 Publisher Name : IJCRT | www.ijcrt.org | ISSN : 2320-2882

 Subject Area: Social Science All

 Author type: Indian Author

 Pubished in Volume: 13

 Issue: 9

 Pages: a763-a777

 Year: September 2025

 Downloads: 53

  E-ISSN Number: 2320-2882

 Abstract

Girls in India confront a complex web of interrelated challenges that undermine their health, education, safety and life chances. This paper synthesizes national surveys, government reports, NGO analyses and peer reviewed studies to examine seventeen core issues affecting girls, including skewed sex ratios, period poverty, anaemia, limited healthcare access, mental health crises, sexual violence, dowry and domestic abuse, child marriage, school dropout, employment and political underrepresentation, superstition driven stigma, cyber harassment and the pressures of non-traditional family choices. Despite these adversities, Indian girls demonstrate remarkable resilience, emotional intelligence and leadership potential. Drawing on evidence from NFHS, NCRB, UNICEF, MOSPI, NITI Aayog and leading research articles, this study highlights both structural failures and promising programmatic responses. The review concludes with targeted policy priorities to strengthen health services, expand educational retention, improve legal redress and community norms, and invest in girls' economic and civic empowerment.


Licence: creative commons attribution 4.0

  License

Creative Commons Attribution 4.0 and The Open Definition

 Keywords

Gender Inequality, Child Marriage, Anaemia, Mental Health Challenges, India, Women's Empowerment, Adolescent Girls, Superstitions, Resilience, Education, Social Stigma

  License

Creative Commons Attribution 4.0 and The Open Definition


  Paper Title: Secure Pattern Based Captcha Enhanced Resource Booking System

  Author Name(s): Dr. Sowmya K S, Rakesh, Supreeth T N, Chandan D S

  Published Paper ID: - IJCRT2509092

  Register Paper ID - 286830

  Publisher Journal Name: IJPUBLICATION, IJCRT

  DOI Member ID: 10.6084/m9.doi.one.IJCRT2509092 and DOI :

  Author Country : Indian Author, India, 560019 , Bangalore, 560019 , | Research Area: Science and Technology

Published Paper URL: http://ijcrt.org/viewfull.php?&p_id=IJCRT2509092
Published Paper PDF: download.php?file=IJCRT2509092
Published Paper PDF: http://www.ijcrt.org/papers/IJCRT2509092.pdf

  Your Paper Publication Details:

  Title: SECURE PATTERN BASED CAPTCHA ENHANCED RESOURCE BOOKING SYSTEM

 DOI (Digital Object Identifier) :

 Pubished in Volume: 13  | Issue: 9  | Year: September 2025

 Publisher Name : IJCRT | www.ijcrt.org | ISSN : 2320-2882

 Subject Area: Science and Technology

 Author type: Indian Author

 Pubished in Volume: 13

 Issue: 9

 Pages: a754-a762

 Year: September 2025

 Downloads: 116

  E-ISSN Number: 2320-2882

 Abstract

This paper presents a Secure Pattern-Based CAPTCHA-Enhanced Resource Booking System designed to safeguard online resource reservation portals from automated attacks. The system integrates a unique pattern-based CAPTCHA mechanism to improve security while maintaining user convenience. Implemented within a college facility management context, this system ensures that only legitimate users can book resources such as auditoriums and sports facilities. Experimental results demonstrate the system's robustness against bot attacks and enhanced user experience compared to traditional CAPTCHA systems.


Licence: creative commons attribution 4.0

  License

Creative Commons Attribution 4.0 and The Open Definition

 Keywords

Secure CAPTCHA, Pattern-Based CAPTCHA, Resource Booking System, Bot Prevention, College Facility Management, User Authentication

  License

Creative Commons Attribution 4.0 and The Open Definition


  Paper Title: Comparative Nutritional Evaluation of Pearl Millet Flour: A Study on Moisture, Ash, Alkalinity, and Calcium Content Across Selected Commercial Brands

  Author Name(s): Muskan patel, Dr. Manju Gupta, Dr. Maneesha Jain

  Published Paper ID: - IJCRT2509091

  Register Paper ID - 292424

  Publisher Journal Name: IJPUBLICATION, IJCRT

  DOI Member ID: 10.6084/m9.doi.one.IJCRT2509091 and DOI :

  Author Country : Indian Author, India, 482001 , jabalpur, 482001 , | Research Area: Chemistry All

Published Paper URL: http://ijcrt.org/viewfull.php?&p_id=IJCRT2509091
Published Paper PDF: download.php?file=IJCRT2509091
Published Paper PDF: http://www.ijcrt.org/papers/IJCRT2509091.pdf

  Your Paper Publication Details:

  Title: COMPARATIVE NUTRITIONAL EVALUATION OF PEARL MILLET FLOUR: A STUDY ON MOISTURE, ASH, ALKALINITY, AND CALCIUM CONTENT ACROSS SELECTED COMMERCIAL BRANDS

 DOI (Digital Object Identifier) :

 Pubished in Volume: 13  | Issue: 9  | Year: September 2025

 Publisher Name : IJCRT | www.ijcrt.org | ISSN : 2320-2882

 Subject Area: Chemistry All

 Author type: Indian Author

 Pubished in Volume: 13

 Issue: 9

 Pages: a751-a753

 Year: September 2025

 Downloads: 63

  E-ISSN Number: 2320-2882

 Abstract

This study evaluates and compares the nutritional properties of pearl millet flour (Bajra) from three commercial brands--Smita Grah Udhyog, Patanjali, and Manan. Parameters assessed include moisture content, total ash, water-soluble and insoluble ash, alkalinity of water-soluble ash, and calcium concentration. Smita Grah Udhyog samples recorded the highest total ash and calcium content, suggesting superior mineral density, while Patanjali showed better mineral bioavailability due to higher water-soluble ash. Natural indicator China rose was used to assess alkalinity. These findings provide insight into the nutritional quality of pearl millet flour, guiding consumer choices and contributing to food security.


Licence: creative commons attribution 4.0

  License

Creative Commons Attribution 4.0 and The Open Definition

 Keywords

Keywords: Pearl millet flour, ash content, calcium, alkalinity, moisture, nutritional quality, commercial brands

  License

Creative Commons Attribution 4.0 and The Open Definition


  Paper Title: Decoding collagen motifs to understand how cells sense and respond to the matrix

  Author Name(s): Peter Sung Kyu Kim

  Published Paper ID: - IJCRT2509090

  Register Paper ID - 293406

  Publisher Journal Name: IJPUBLICATION, IJCRT

  DOI Member ID: 10.6084/m9.doi.one.IJCRT2509090 and DOI :

  Author Country : Foreign Author, United Kingdom, CB24 1DW , CAMBRIDGE, CB24 1DW , | Research Area: Biological Science

Published Paper URL: http://ijcrt.org/viewfull.php?&p_id=IJCRT2509090
Published Paper PDF: download.php?file=IJCRT2509090
Published Paper PDF: http://www.ijcrt.org/papers/IJCRT2509090.pdf

  Your Paper Publication Details:

  Title: DECODING COLLAGEN MOTIFS TO UNDERSTAND HOW CELLS SENSE AND RESPOND TO THE MATRIX

 DOI (Digital Object Identifier) :

 Pubished in Volume: 13  | Issue: 9  | Year: September 2025

 Publisher Name : IJCRT | www.ijcrt.org | ISSN : 2320-2882

 Subject Area: Biological Science

 Author type: Foreign Author

 Pubished in Volume: 13

 Issue: 9

 Pages: a747-a750

 Year: September 2025

 Downloads: 50

  E-ISSN Number: 2320-2882

 Abstract

Collagen serves as both scaffold and signal in mammalian tissues, providing tensile strength while encoding biochemical cues in its triple helical sequence. A central question in matrix biology is how cells convert this motif level information into adhesion, migration, differentiation, and repair. In skin and many soft tissues, fibrillar collagens I and III dominate the mechanical landscape; cells interpret these fibers largely through collagen binding integrins (?1?1, ?2?1, ?10?1, ?11?1) and the discoidin domain receptors DDR1/DDR2. Systematic Collagen Toolkits devised in Richard Farndale's laboratory (University of Cambridge) mapped short triple helical peptides and defined key motifs - GFOGER/GxOGER for integrin ?2?1 and related ?I containing integrins, GLOGEN/GROGER for ?1?1 preference, and GVMGFO for DDRs, thus revealing how cells "read" collagen at amino acid resolution. Integrating structural, biochemical, and functional data, this review synthesizes how fibroblasts, keratinocytes, endothelial cells, chondrocytes, immune cells, and platelets use these receptors to extract meaning from collagen, with special attention to the HUVEC study by Hunter et al. (2022) that disentangles integrin usage during adhesion, migration, and tube formation on collagen. Finally, I discuss how motif aware insights now inform biomaterial design, wound care, dermatology, and aesthetics, where engaging or modulating specific collagen-receptor axes may improve outcomes.


Licence: creative commons attribution 4.0

  License

Creative Commons Attribution 4.0 and The Open Definition

 Keywords

Collagen; Integrins ?1?1/?2?1/?10?1/?11?1; Discoidin domain receptors; Collagen Toolkit; GFOGER; GLOGEN; Endothelial cells; HUVEC; Mechanotransduction

  License

Creative Commons Attribution 4.0 and The Open Definition



Call For Paper December 2025
Indexing Partner
ISSN and 7.97 Impact Factor Details


ISSN
ISSN
ISSN: 2320-2882
Impact Factor: 7.97 and ISSN APPROVED
Journal Starting Year (ESTD) : 2013
ISSN
ISSN and 7.97 Impact Factor Details


ISSN
ISSN
ISSN: 2320-2882
Impact Factor: 7.97 and ISSN APPROVED
Journal Starting Year (ESTD) : 2013
ISSN
DOI Details

Providing A digital object identifier by DOI.org How to get DOI?
For Reviewer /Referral (RMS) Earn 500 per paper
Our Social Link
Open Access
This material is Open Knowledge
This material is Open Data
This material is Open Content
Indexing Partner

Scholarly open access journals, Peer-reviewed, and Refereed Journals, Impact factor 7.97 (Calculate by google scholar and Semantic Scholar | AI-Powered Research Tool) , Multidisciplinary, Monthly, Indexing in all major database & Metadata, Citation Generator, Digital Object Identifier(DOI)

indexer
indexer
indexer
indexer
indexer
indexer
indexer
indexer
indexer
indexer
indexer
indexer
indexer
indexer
indexer
indexer
indexer
indexer
indexer
indexer
indexer
indexer
indexer
indexer
indexer
indexer
indexer
indexer
indexer
indexer
indexer
indexer
indexer