Volume 11 | Issue 7 |

 Abstract

Bladder cancer is quite common in India. A very high incidence is seen in some of the European countries. The etiopathology remains unclear, ranging from smoking, chemical carcinogens, parasites to chronic low grade infection of the urinary bladder - cystitis. The prognosis depends upon many factors, most important of which is, whether the cause is invasive or non-invasive. Besides this, some gene polymer films and other tumor markers have been used in determining the prognosis. Of the several stem cell markers, ALDH-1 is also a stem cell marker which has been found to be associated with the malignancy and prognosis. The other stem cell markers are CD44, CD133, CD24. The present study had been planned to study the presence of ALDH-1 positive cancer stem cells in urinary bladder cancer.

Licence: creative commons attribution 4.0

  License

Creative Commons Attribution 4.0 and The Open Definition

 Keywords

Bladder Cancer, Tumor Markers

  License

Creative Commons Attribution 4.0 and The Open Definition

 Abstract

Now a day's infrastructure development plays a major role in the civilization. More over transportation facilities also required for the development. Majorly in developing countries like India it requires an economic way of transportation facilities. In general the roads affected to some problems like wear and tear, less durability and loosing strength due to water absorption. It causes damages to pavements and the fuel consumption to transport the things from one place to another place is more, the vehicle is also affected moreover. To reduce the problems occurring because of moisture absorption and temperature variations, we require the material to resist the damages on the road surface and to the base courses. For this the material called Zycotherm used to protect the surface of pavement from the characteristic of moisture absorption and temperature failures. By using this material we can easily reduce the failure of pavement against sunlight, heat, and ignition, source of spark, rain, and standing of water on surface. It reduces the surface tension of asphalt binder and reduces viscosity of binder. Using this Zycotherm can improves field compaction up to 90oC, eliminates odour & stripping, reduce stickiness and more over the basis of the thesis is to find out change in the physical properties of the bitumen by modifying it with different fillers. The types of fillers used in project are Stone dust, Lime, Brick powder, OPC & Fly ash.

Licence: creative commons attribution 4.0

  License

Creative Commons Attribution 4.0 and The Open Definition

 Keywords

bitumen, additives materials, fly ash, brick powder.

  License

Creative Commons Attribution 4.0 and The Open Definition

 Abstract

??????????? ??????? ?????????? ??????? ??????? ??????? ? ?? ??????? ????????? ?????? ? ??? ??????? ???? ????????? ??????? ???? ? ??????????? ??????????? ??????????? ??????????? ??????????? ????????????? ??? ????? ??? ???? ??????? ? ?????? ???? ?????? ???? ? ??? ??????? ???????? ??? ?????????? ?

Licence: creative commons attribution 4.0

  License

Creative Commons Attribution 4.0 and The Open Definition

 Keywords

????????? ?????????????? ????????????? ?????????? ?????????? ?????????? ?????????? ????????????? ? ????????????????

  License

Creative Commons Attribution 4.0 and The Open Definition

 Abstract

Marketing holds the key to the success in any business today. One can witness a dramatic global shift from 'production-dominated' to a 'consumer-oriented' business culture. Marketing is thus about winning the customer. Understanding what consumers want and supply them efficiently, conveniently and attractively are the key factors in marketing. Marketing adds value. It takes what otherwise could be an ordinary commodity that is made into a highly sought-after brand. Marketing is essentially persuasion. It is also about communication - communicating and highlighting in favour of one's brand.

Licence: creative commons attribution 4.0

  License

Creative Commons Attribution 4.0 and The Open Definition

 Keywords

Marketing, Promotion, detergents

  License

Creative Commons Attribution 4.0 and The Open Definition

 Abstract

???????????? ?????? ??????? ??????????? ??? ?????????? ?????????? ??????????????? ??????? ??????????? ?????? ????????? ???????? ????????? ? ?????????????? ???????? ????????????????????? ????? ??????? ???????????? ? ?????-??????????????????? ????????????? ????????????????? ???????? ????????? ????? ? ??? ???????????????? ? ??????? ??????????????? ???????? ????????????? ??????? ???????????????? ????? ?????? ? ???? ????????? ' ?? ????????????? ' ??? ????????????? ????? ????????????????? ???? ????? ??????????? ?????? ? ???? ??????? ?????????????????? ?????????????? ???????? ?

Licence: creative commons attribution 4.0

  License

Creative Commons Attribution 4.0 and The Open Definition

 Keywords

?? ????????????? ??? ?????? ???????, ?? ????????????? ??? ?????? ????????

  License

Creative Commons Attribution 4.0 and The Open Definition

 Abstract

Automotive radiator is key component of engine cooling system. Radiator thermal analysis consist sizing and rating of head exchanger . Radiator Size Mainly depends on head rejection requirement. Head Transfer Calculations are important fundamentals to optimize radiator size. Automotive manufactruers use 1-D simulation software to decide radiator size. This paper focuses on thermal analysis of radiator theoretically using E-NTU method and its validation by simulation approach.

Licence: creative commons attribution 4.0

  License

Creative Commons Attribution 4.0 and The Open Definition

 Keywords

Automotive radiator ,Head transfer , Rating , Simulation, Sizing

  License

Creative Commons Attribution 4.0 and The Open Definition

 Abstract

OpenAI has released a new version of ChatGPT, a sophisticated natural language processing system which is able to hold natural conversations by preserving and responding to the context of the discussion. However, ChatGPT has also been utilized in negative aspects despite its usage in different fields of applications. Data has been gathered regarding the effectiveness and usability of this tool for completing examinations, programming assignments, and term papers. This work has analyzed the impact of ChatGPT system in the field of education especially in the field of computer science higher education and also evaluated how it is misused in different levels of applications, ranging from utilizing it as a consultant to simply copying its outputs. The analysis indicates that ChatGPT is able to cope up with "Programs" and performs better. It is not able to compete effectively in other fields like examinations / term papers.

Licence: creative commons attribution 4.0

  License

Creative Commons Attribution 4.0 and The Open Definition

 Keywords

Artifical Intelligence, ChatGPT, education, Virtual Assistant, Computer Security.

  License

Creative Commons Attribution 4.0 and The Open Definition

 Abstract

The emergence of innovation in small and medium scale enterprises (SMEs) is vital to achieve economic growth. Hence, product innovations in attaining competitive advantage to achieve desired level of economic growth in Nigeria have recently emerged as one of the most significant subjects in the context of the common marketplace. This made it imperative for the study to conduct an analysis of the Role of Product Innovation on Small and Medium Scale in Abia State of Nigeria. Primary data sourced from selected SMEs clusters in Aba, Abia State were used for the study. The study utilized Pearson correlation technique and Z-test analytical techniques in investigating the role of product innovation on the survival of Small and Medium Enterprises in Abia State. The study based on the results revealed that there is a weak positive relationship of about 34% between product innovation improving the productivity of SMEs in Nigeria and product innovation by SMEs attracting government support in Nigeria within the study period. The study further revealed that the most relevant influence on business competitiveness for the SMEs is the defensive strategies. The study therefore recommended that government should encourage innovative SMEs development through the provision of incentives to SMEs and standing as a guarantor for loans given to aspiring entrepreneurs and innovators.

Licence: creative commons attribution 4.0

  License

Creative Commons Attribution 4.0 and The Open Definition

 Keywords

Product Innovation, Business Competitiveness, Survival, SMEs

  License

Creative Commons Attribution 4.0 and The Open Definition

 Abstract

The Quality by Design (QbD) methodology has recently been used in the creation of pharmaceutical formulations. Modern and reliable quality by design indicates that structure plays a key role in the process of getting drugs of high quality. QbD approach guarantees security, adequacy and nature of item with an undeniable degree of efficiency. Executing into practice the QbD to effective topical dose structures underlying phases. Incorporating QbD methodologies involves creating a quality target product profile (QTPP) and selecting crucial quality attributes (QAs) to develop a plan for a quality-based, non-exclusive, beneficial dermatological product. Characterizing the quality target product profile (QTPP), a list of quality attributes (QAs) that are intended to be present in the finished product, is the first stage in developing an item using this effective process. The limitations of the assembling approach as well as the fixes used have an impact on these quality attributes. Therefore, it is necessary to indicate critical material attributes (CMAs) and critical process parameters (CPPs). It is deliberate, pragmatic and hazard-based approach in drug improvement. Administrative specialists overall additionally support the transformation & Quality by Configuration execution methodology in drug advancement. QbD apparatuses like plan of trial, hazard appraisal, and interaction scientific innovation help to lay out a control procedure for each medication item with a choice of ceaseless observing and improvement for a quality drug product. The purpose of this brief review is to explain how pharmaceutical Quality by Design is perceived.

Licence: creative commons attribution 4.0

  License

Creative Commons Attribution 4.0 and The Open Definition

 Keywords

Quality by design (QbD), quality target product profile (QTPP), critical material ascribes (CMAs), critical process parameters (CPPs), quality attributes (QAs), Degree of efficiency

  License

Creative Commons Attribution 4.0 and The Open Definition

 Abstract

Girls and boys see gender inequality in their homes and communities every day - in textbooks, in the media and among the adults who care for them. Parents may assume unequal responsibility for household work, with mothers bearing the brunt of caregiving and chores. The majority of low-skilled and underpaid community health workers who attend to children are also women, with limited opportunity for professional growth. And in schools, many girls receive less support than boys to pursue the studies they choose. This happens for a variety of reasons: The safety, hygiene and sanitation needs of girls may be neglected, barring them from regularly attending class. Discriminatory teaching practices and education materials also produce gender gaps in learning and skills development. As a result, nearly 1 in 4 girls between the ages of 15 and 19 are neither employed nor in education or training - compared to 1 in 10 boys.

Licence: creative commons attribution 4.0

  License

Creative Commons Attribution 4.0 and The Open Definition

 Keywords

H: Hypothesis, df: degree of freedom

  License

Creative Commons Attribution 4.0 and The Open Definition