Volume 8 | Issue 7 |

 Abstract

Introduction: Acute disseminated encephalomyelitis (ADEM) is a demyelinating central nervous system disorder. The experience in children in our area is limited. Purpose: We describe a cohort of consecutive children with ADEM. Methods: Clinical and MRI of brain characteristics, treatment and outcome of a series of ADEM hospitalized in PICU, Oran University Hospital center (Algeria) from January 2011 to may 2016 were reviewed. Results: There were 07 males and 03 females. The mean age (median) at onset was 48 months [range, 6 �132 months]. All children had a prodromal event (infectious 08 cases or vaccination 02 cases). The mean interval between the febrile prodrome and the beginning of neurologic disturbance was 14 days (range, 3 to 30 days). Limb weakness (02 cases), ataxia (02 cases), ophtalmoplegia (02 cases) and acute hemiparesis (02 cases) were the most prominent initial findings. Aphasia was noticed in one patient. Seizure was observed in 07 patients. Consciousness disturbance (n=5) evolved into coma with cardiomyopathy of stress in one patient. CSF lymphocyte pleocytosis was found in 3 patients (9 � 208 cells/mm3). Initial MRI showed a deep gray matter involvement in 6 cases. Electroencephalogram (EEG) showed slowing of background activity in 04 patients. 05 patients were treating with IV immunoglobulin alone and 03 with high-dose IV methylprednisolone pulse. Among 10 patients, five had long-term neurological squeals. Conclusion: We conclude that early diagnosis and prompt treatment of ADEM will probably reduce morbidity and the seizures are not uncommon in ADEM.

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Encephalopathy, ADEM, Brain Magnetic Resonance Imaging, Children, Outcome

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Working capital plays the same role in a business concern as the role of the heart in a human body. If it is carried out effectively, efficiently and consistently, that will assure the financial health of an organization. In this study, the data of five top companies which is taken in Indian Retail Industries between the years 2014-2019, has been used. Return on Assets (ROA) has been used as indicators of company�s profitability and account receivable days, account payables days and inventory turnover days have been used as independent variables. Multiple regression, correlation methods, t-test and Altman Z score model have been used in empirical analysis. The result of analysis indicates that the ROA has positive significant relationship with ARD and negative significant with APD while ROA has negative insignificant relationship with ITD. The present study explores the impact of working capital management on the profitability of Indian Retail industry and its analysis the financial health during the study period. The study brings out a meaningful conclusion based on the findings of the study.

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Retail Industry, ROA, ARD, APD, ITD, Altman Z score model

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The Coronavirus pandemic and therefore the ensuing lockdown have forced schools and colleges across India to temporarily shut and this unprecedented move had created an enormous gap within the education bodies despite the central and government doing their best to support for e-learning and online education. Globally, the Indian Education sector is amongst the largest, with an extensive network of more than 1.4 million schools and 993 Universities, 39931 Colleges, and 10725 Stand Alone Institutions listed on the AISHE web portal. As the Indian education system was mostly based on the offline system and classes. Most of the primary and secondary schooling sector was all based on offline education system has to opt the online classes for empowering the education and for the benefits of the students. Many schools within the country have switched to online classes due to the lockdown, but one in four students is unable to attach because they don�t have a laptop, desktop, or tablet, consistent with a survey by economic times[1].

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EDUCATION SYSTEM,COVID-19,STUDENTS

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Phyco-remediation is a technology deal with the use of algae for remediation purpose of waste water. The present research work has been carried out to remove total dissolved solids from synthetic water. Two commonly found macro-algae were utilized for treatment. The total dissolved solids of synthetic water were kept in range 500-35000 mg/l. The selected algal species were Chara & Oedogonium. The experiments were carried out in batch studies for 20 days. The results conclude that Oedogonium reduces 39 % and Chara 40 % of total dissolved solids respectively. The present methodology is a simple, safe, reliable and cost-effective method for biological treatment using algae to remove total dissolved solids from water & wastewater through phyco-remediation process.

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Water, Synthetic water, Algae, Total Dissolved Solids, Phyco-remediation, Biological Treatment

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Unani system is one of the ancient system deals with the management of health and disease. The unique realistic approach and clinical success of the unani system of medicine arise from its fundamental principles and the existance of this system till now, itself is an evidence of validity of its principles. However, the long term existence of any system is based on a continuous search for new knowledge through research, developement by using modern technique and equipment, and also introducing fresh and newer concept to strengthen it's existence. The concept proposed should be scientific and should give a valid reason and solid evidences to proof when asked for. New research now a days have only been limited up to the translation of old classical data which is at least helping the newer researchers, physicians and students of medicine to understand the unani concept and to enlightened the quotes said by unani physicians long time ago. In this way, the data is made accessible. Research should be made more vast and deep. Ironically now a days, research is done just to compare unani system of medicine with the modern (allopathic system) and research done in the light of modern medicine protocol without considering the principles of unani system of medicine. There is a need to work on unani drugs, Discover new drugs, Do research of a drug in a new aspect, Do extensive research to treat the chronic diseases, concentrate on Possibilities of unani system of medicine, and focus on problems of Systen. Inside the article, the author stands for the need to understand possibilities and Problems of unani system of medicine.

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Fundamental Principles, Drug, Protocol, Research.

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The objective of the study is to investigate the impact of demonetization on Indian economy. The study traces the practice of demonetization adapted by other developing economies including India. �Demonetising is the act of removing the current currency from the economy and replacing it with new currency.�1 It is also defined as �the act of sripping a currency unit of its status as legal tender.� 2 Demonetisation was also adopted by Ghana, Nigeria, Myanmar, Soviet union, Russia, North Korea and India mainly for reducing black money, black market and anticorruption measure. Regarding implications of Demonetisation there are positive and negative view expressed by the persons form different sectors, have also been reviewed by the study.

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ANALYSIS OF DEMONETIZATION IMPACT ON INDIAN ECONOMY.�

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The sixth revision of IS:1893 (Part ):2016, "Criteria for Earthquake Resistant Design of Structures" has been published by Bureau of Indian Standards recently in December 2016. In this new code many changes have been included considering standards and practices prevailing in various countries including India. The Indian seismic code IS:1893 has been revised after a gap of 14 years. This works aims at studying the revisions in various clauses of the new IS:1893 (Part 1):2016 and comparing it with the earlier version. The method of analysis and design of multi-storey residential buildings G+3, G+14 and G+24 located in zone III, IV and V under different soil conditions in both static and dynamic method with old and new IS:1893. The newly revised code has introduced a clause for effect of Unreinforced masonry (URM) infill walls in buildings, minimum width of column has changed into 300 mm and modifications done on response spectra. These are primary provisions considered in analysis of these buildings. The effects of diagonal struct provided in various locations in buildings with different conditions were analysed in the clause for URM infill walls. this project aims at under standing the relevance of the Indian standard codes that are used for design of various building elements using Staad Pro software under seismic load and wind load acting on the structure and investigating sufficient changes in the seismic performance of building while considering both the codes. If considerable variations in the results are identified between the both codes, then the currently existing buildings that had been constructed before implementing the revision in 2016 need to be modified by suitable retrofitting schemes.

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Staad Pro, IS:1893-2002; IS:1893-2016; Seismic performance; response spectra; equivalent static method; time history method; URM infill walls

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A Data Center Environment Setup for a large Manufacturing Company, wherein every internal business unit needs certain levels of IT resources such as Servers, Storage, Network etc. to perform their day to day operations like, HR department, Finance, R&D, Production Unit, Education Services etc. Company follows metered solution for IT resources so that, their resource utilizations can be cross charged by end of each month on a consumed capacity basis, in order to meet company�s overall IT budget, Operational expenditures and future IT asset procurements. Thus, company can manage tech refresh and new technology adoptions effectively and efficiently. Internal IT division follows a flexible consumption model to meet this requirement and uses latest technologies to have a robust system.

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Data Centre Environment, consumed capacity, IT Budget, Operational Expenditures, Asset procurement

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COVID 19 has affected humans in every possible way. According to the WHO Globally, as of 10:34am CEST, 9 July 2020, there have been 11,841,326 confirmed cases of COVID-19, including 544,739 deaths. Most affected regions include America followed by Europe. Chloroquine and hydroxychloroquine are commonly prescribed worldwide. When used for malaria prophylaxis, chloroquine is generally administered at a dose of 500 mg per week starting 2 weeks before and continuing for up to 8 weeks following endemic exposure. Long-term use can be considered for the treatment of chronic autoimmune diseases, such as rheumatoid arthritis and systemic lupus erythematosus. Hydroxychloroquine is typically prescribed as a 400 mg weekly dose when used for malaria chemoprophylaxis and as a 200 to 400 mg daily dose in patients with systemic lupus erythematosus or with rheumatoid arthritis on 17 June 2020, WHO announced that the hydroxychloroquine (HCQ) arm of the Solidarity Trial to find an effective COVID-19 treatment was being stopped. This review article discuss historical perspective and development of chloroquine analogues, current research work on chloroquine analogue, advance treatment used for the treatment of the COVID19 and new drugs as well as various test available for the COVID 19.

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Chloroquine, Hydroxychloroquine, COVID19, Rheumatoid Arthritis

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Abstract The study aims at analysing the impact of Covid-19 pandemic induced lockdown on migrant workers in India and to focus upon the recently announced Garib Kalyan Rojgar Abhiyan as a remedy for minimising the problems of migrant workers. Workforce in general and migrant workers, in particular are highly affected by the Covid-19 pandemic induced lockdown in India. Around four crore migrant labours are engaged in various works in different parts of the country as per announcement of central Government official. Most of the migrant workers are engaged in informal sector. They are not capable to save much money to bear the cost of their livelihood during the period of Covid-19 induced long lockdown. Most of migrant workers have lost their jobs due to shutting of factories and business houses. Due to lack of food, shelter and fear of virus, majority of stranded workers forced to return their native place though there remains uncertainty for getting job. Government of India announced the Garib Kalyan Rozgar Abhiyan (GKRA) as an instrument to cope up with the problems of unemployment in rural areas arising out of Covid-19 pandemic. In this backdrop this paper, based on secondary data is an effort to focus upon the Garib Kalyan Rozgar Abhiyan as an instrument for minimising the problems of migrant workers as well as in the direction of self reliant villages. Various articles, newspapers, Government Reports are consulted to compose the study. The paper is to be divided into three sections. Section- I is an introductory in nature, highlighting methodology, objectives of the study and review of literature, Section � II deals with discussion and analysis, Section � III remains for conclusion and suggestions.

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Key words: Covid-19, migrant workers, GKRA

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