Volume 13 | Issue 6 |

 Abstract

The field of organoids has witnessed remarkable advancements, emerging as a transformative tool in biomedical research. Organoids are three-dimensional, multicellular structures derived from stem cells that replicate the architecture and functionality of real organs. This review aims to comprehensively explore the origin, development, and applications of organoids, emphasizing their potential in drug discovery, regenerative medicine, and disease modeling. A significant focus is placed on the concept of Organoid Intelligence (OI), envisioned as a form of genuine biological computing. OI integrates organ-on-chip systems with computational frameworks, offering revolutionary possibilities in biological computing and artificial intelligence. The paper delves into the application of machine learning (ML) in pharmacy, highlighting how ML algorithms enhance data analysis, predict drug efficacy, and personalize medicine in conjunction with organoid systems. Additionally, the review examines the ethical dilemmas associated with OI, particularly in the context of the Baltimore Declaration. This declaration emphasizes the need for transparency' reproducibility, and ethical considerations in scientific research. By addressing the ethical challenges, this paper seeks to ensure the responsible development and application of OI technologies. The convergence of organoids, OI, and ML promises to redefine the boundaries of computational biology and pharmaceutical sciences. This research review not only provides insights into the technological advancements but also underscores the importance of ethical and regulatory frameworks to guide the future of these innovations. Through a holistic approach, it aims to shed light on the transformative potential of organoids and their implications for science and society.

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 Keywords

Organoids, Drug Discovery, Personalized Medicine, Disease Modeling, Pharmacy Applications. Introduction

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This paper aims at finding the Life Skills and Adjustment of Prospective teachers. A simple random sampling technique was followed to select 1000 prospective teachers from Guntur district of Andhra Pradesh. The researcher construct and standardized the life skills questionnaire and adopted Adjustment Inventory for College Students (AICS) which was developed and standardized by A.K. P. Sinha, and R.P. Singh using. Mean, SD and 't' values were calculated. The study revealed that there is significant difference in the adjustment of prospective teachers w.r.t the variables - Gender and Locality. Positive correction of life and adjustment of prospective teachers.

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Life Skills, Adjustment, Prospective teachers

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Environmental problems of the modern world--climate change, deforestation, pollution, biodiversity loss--demand a multidisciplinary response that includes literature and the humanities. Ecocriticism, an interdisciplinary field of literary criticism, has emerged as a vital lens for examining the relationship between literature and the natural environment. This paper explores the evolution, theories, and methodologies of ecocriticism, its integration with environmental literature, and the transformative potential it holds for ecological consciousness. Drawing from both Western and non-Western traditions, the study investigates how literature serves not only as a mirror of ecological thought but also as a catalyst for environmental activism and ethical re-engagement with nature. The paper also reviews prominent texts and authors, analyzes theoretical frameworks, and assesses the future trajectory of ecocritical studies in light of ongoing environmental challenges.

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 Keywords

Ecocriticism, Environmental Literature, Nature Writing, Ecofeminism, Deep Ecology, Anthropocene, Climate Fiction

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Enteric coated tablets are solid unit dosage forms intended for oral delivery; they are made to avoid the stomach and release the medication in the small intestine instead. The word "enteric" indicates small intestine; therefore enteric coatings prevent release of medication before it reaches the small intestine. Most enteric coatings work by presenting a coated surface that is stable at the highly acidic pH found in the stomach, but breaks down rapidly at a less acidic (relatively more basic) pH. Enteric coating materials consist of fatty acids, waxes, shellac, polymers, plant fibers, CAP, CAT, PVAP, and HPMCP. This study discusses enteric coating, including its optimal qualities, advantages, and disadvantages. It also discusses the different polymers utilized, their chemical structures, drug selection and mechanism criteria, and the production and assessment processes for enteric coated tablets. Due to their advantages over traditional drug delivery methods, which include longer dose intervals and higher patient compliance, these have recently piqued the interest of several formulators. The study provides an overview of the recent advances in enteric coated tablet

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Coating Process, Evaluation, Enteric coated tablet, Methods of Enteric Coated, ideal characteristic

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Life is not same for all. Women face discrimination and face competition in every sectors of their lives. Every day thousands of women struggle to earn their living especially because of the competition with the men of the society. Women as hawkers are truly vulnerable to a no. of exploitations and harassments. Nearly thousands of women especially from the later middle aged group take up vendoring in local trains to sustain from their poverty. The research selected 3 respondents who hawk in the main line trains running in between Barrackpore and Sealdah, adopting convenient sampling and study their living conditions. These respondents were interviewed and participant observation method was followed. It is noted that the train hawkers follow the Railway Act and get the licenses through Sealdah Hawkers Union. The study mainly focuses on everyday life of these three female hawkers and the complexities that led them to be in this informal sector. The study also examines how they face the vulnerabilities of exploitations. . Everyone constantly puts a man before women no matter how much efforts she put in for balancing everything. Women and men face unequal treatment all over the world in all sectors of their lives. So it is important to know more about these unnoticed lives which we see every day.

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Gender inequality, daily hardships, hassle, harassment, exploitation.

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18s rRNA, Microscopy, Malaria Diagnosis, Plasmodium falciparum, Children, Nigeria, Molecular Diagnostics

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This research paper delves into the critically acclaimed film Avatar, directed by James Cameron. Released in 2009, the film captured worldwide attention for its groundbreaking visual effects, immersive storytelling, and thought-provoking themes. The paper delves into the film's narrative structure, thematic depth, visual spectacle, and environmental allegory, offering an extensive examination of its significance in contemporary cinema. By exploring the film from multiple angles, we gain insights into its impact on the film industry, its social commentary, and its role in shaping public discourse on environmental issues. The paper on the movie Avatar has yielded several significant findings that contribute to a deeper understanding of the film's impact and relevance. Through an extensive analysis of Avatar's technological advancements, the paper uncovered ground-breaking developments in 3D technology and visual effects. It was found that the movie is revolutionized in the use of 3D in cinema, setting new standards for immersive viewing experiences. The research paper also explored the film's innovative use of motion capture techniques, revealing the level of detail and realism achieved in the portrayal of the film's characters and performances. Additionally, the paper examined the film's narrative and thematic elements, revealing the profound cultural and social impact of Avatar. The research identified the film's environmental message and its ability to spark discussions and raise awareness about the importance of ecological conservation and sustainability. Furthermore, the paper sheds light on Avatar's global reception and influence, uncovering its significant commercial success and its enduring popularity among audiences. The findings of this research paper provide valuable insights into the movie's technological achievements, thematic depth, and cultural impact, contributing to a comprehensive understanding of its significance in the realm of cinema.

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Avatar, Environmentalism, Colonization, Cultural Impact, Technological Innovations, Film Industry, 3D Technology.

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This paper critically examines the trajectory of feminist protest in Nayantara Sahgal's novels A Time to Be Happy (1958), This Time of Morning (1965), and Rich Like Us (1985). The study examines the development of female resistance through the text and theory of these works in an elaborate textual and theoretical analysis to outline a transitional point between vague psychological resistance and distinct political and personal disobedience. By placing the narratives of Sahgal in the larger socio-political scenario in the post-independence India, the present paper focuses on the interaction of gender, class and politics and bring to the fore the role of Sahgal as a feminist literary critic. Relying on feministic theories of such thinkers as Beauvoir, Crenshaw, Spivak, et al., the paper establishes the importance of literature as an effective expression force and the tool of developing feminist awareness.

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Feminist Resistance, Indian English Literature, Postcolonial Women's Writing, Autonomous Female Identity, Gender and Power Dynamics

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This anti-ageing face serum is a scientifically formulated skincare solution designed to target visible signs of ageing, including fine lines, wrinkles, and loss of elasticity. Enriched with potent active ingredients such as vitamins A and E, Essential fatty acid, retinol, and antioxidants, the serum works to deeply hydrate the skin, stimulate collagen production, and protect against environmental stressors. Lightweight and fast absorbing, the formula penetrates the skin's surface to promote a smoother, firmer, and more radiant complexion. Suitable for all skin types, this serum offers a non-invasive approach to youthful, revitalized skin with regular use. The face serum was formulated using standard excipient including apricot oil, glycerine, coconut oil, sandalwood oil, olive oil and preservatives. The final antiaging formulation was tested for anti its antiaging activity and stability. The results demonstrated promising antiaging property with minimal risk of side effects supporting the efficacy of serum combination as cost effective and safe alternative for treating aging of face skin.

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Enriched, Firmer, Minimal, Non-invasive, Potent, Revitalized, Stressors.

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The Government. The technology providers and providers of rural centric offerings would have to come together and create an integrated approach aimed at expanding the rural economy.

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Transforming, Rural, Digital Technology, NGOs.

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Creative Commons Attribution 4.0 and The Open Definition