Volume 9 | Issue 6 |

 Abstract

The mean platelet volume (MPV) is an inflammatory marker which suggest the activation Platelets .There are number of studies which suggest the association between the neoplastic process and metastasis of cancer . Here we have conducted a retrospective analysis to find the role of MPV as a prognostic informative marker in gall bladder cancer This study includes a retrospective analysis of 73 patients with gall bladder cancer who Underwent treatment for gall bladder cancer with curative or palliative intent . MPV was obtained and statistically analysed to find association between the nodal status (N) , overall stage as per American Joint Committee on Cancer (AJCC) staging system, perineural invasion and differentiation of the tumor ,using Statistical Package for the Social Sciences (SPSS) software (IBM corp. version 23). It was seen in this study that MPV values were significantly high in nodal positive cases (OR 3.623 ,95% CI (7.778-1.687) ; p value -0.0001), advanced stage (OR 3.623 ,95 % CI (7.778-1.687) ; p value of 0.0001) , perineural invasion (OR 3.396 , 95 %CI (8.319- 1.387 ) ; p value -0.0001) , poor differentiation (OR 2.327 , 95 % CI (4,651-1.164) ; p value -0.002 ).MPV is an inflammatory marker which relates the nodal positivity in staging and prognostication of gall bladder cancer . This marker is inexpensive and can be done conveniently aiding in ascertaining risk status of gall bladder cancer

Licence: creative commons attribution 4.0

  License

Creative Commons Attribution 4.0 and The Open Definition

 Keywords

gall bladder cancer , mean platelet volume , diagnosis

  License

Creative Commons Attribution 4.0 and The Open Definition

 Abstract

Neo liberalism plays a critical role in affairs of World Trade Organization (WTO), it has allowed ideologies to come in the interplay in spheres of Trade Organization with other states. The interstate interaction reflects in International organization where with the help of repressive strategy, stifling dissent, coercion and use of global International Law to set agendas are promoted with specific objective of favouring the Neo-liberal hegemony of Global North under the leadership of United States Of America(USA). In auspices of the World Trade Organization Neo liberal hegemons of the Global North has placed hierarchy of command which reflects into neo liberal structure of support and global compliance of trade relations, around utilitarian construction of Laiz faire that hegemon state moots and under temporal abstraction reflects in their International business. Neo liberal jurisprudence has broken the last vestiges of realist restraint and capricious interference the cold war era jurists and economists had. The communist influence and contending socio-global political structures pertaining global trade has with rise of the neo-liberalism eventually succumbed.

Licence: creative commons attribution 4.0

  License

Creative Commons Attribution 4.0 and The Open Definition

 Keywords

WTO, Dispute Redressal Mechanism, Neoliberal Jurisprudence

  License

Creative Commons Attribution 4.0 and The Open Definition

 Abstract

Rare causes of vascular parotid swellings that may cause diagnostic error. Indeed, the additional examinations will have to be appropriate thus allowing an adapted therapeutic management. Pseudo-aneurysms of the external carotid artery or its branches are rare [1] and often secondary to trauma. We present the case of a 29-year-old patient who consulted for a left intra-parotid lesion in March 2020 following a shock on the left upward limb of the mandible occurring 4 days before. At the initial clinical examination, he found a palpable mass 2 cm in diameter, deep retro-mandibular, not pulsatile. Angioscan performed in emergency objectified after injection of contrast agent in favor of an aneurysm of the external carotid intra-parotid portion. Pseudo-aneurysms of the extra-cranial arteries are rare and most often post-traumatic, frequently affecting the internal carotid artery [2]. Only 7 cases are described in the literature [3]: 4 on the intra-parotid part of the external carotid artery, 2 on the superficial temporal artery and 1 on the posterior auricular artery [7].The different treatments include observation with regular monitoring, surgical excision, presso therapy and embolization [3,5]. In this case, the treatment consisted of embolizing the external carotid artery. Therefore, it seems to us essential to think about this pathology in case of atypical lesion before any invasive gesture. Although rare, and even if there is no trauma, it seems important to us to evoke the pseudo-aneurysms of the external carotid artery or one of its branches.

Licence: creative commons attribution 4.0

  License

Creative Commons Attribution 4.0 and The Open Definition

 Keywords

pseudo aneurysm; external carotid;embolization

  License

Creative Commons Attribution 4.0 and The Open Definition

 Abstract

Licence: creative commons attribution 4.0

  License

Creative Commons Attribution 4.0 and The Open Definition

 Keywords

Chimeric antigen receptors, CAR T cell therapy, cancer immunotherapy, tumor, FDA approved therapy

  License

Creative Commons Attribution 4.0 and The Open Definition

 Abstract

Controlling and detecting the spread of diseases like COVID-19 is essential in controlling epidemics. The measures to decrease the spread is to detect infected people ad track their previous illnesses. Contact tracing helps to isolate anyone who may be infected, since the virus can be transmitted between people without even showing any symptoms. These previous contacts can be used with mobile devices such as smart watches or smartphones that track the location and contacts through the use of communication technologies like GPS, Wi-Fi, Bluetooth or other cellular networks. This paper evaluates the importance of these technologies and determines the spread of toxic diseases. In this paper, we uses an epidemic model to evaluate productiveness and the measures to be taken, depending on contact tracking technologies from smartphones. The result show us in order to be effective of COVID-19 disease, the contact tracking technology must be accurate, contacts must be tracked quickly. This requirements make smartphone-based contact tracing to turn down the spread of virus in this period.

Licence: creative commons attribution 4.0

  License

Creative Commons Attribution 4.0 and The Open Definition

 Keywords

Mobile computing, social networks, digital epidemiology, epidemic models.

  License

Creative Commons Attribution 4.0 and The Open Definition

 Abstract

एक प्रयास बेहतर एवं नि:शुल्क चिकित्सा की ओर

Licence: creative commons attribution 4.0

  License

Creative Commons Attribution 4.0 and The Open Definition

 Keywords

एक प्रयास बेहतर एवं नि:शुल्क चिकित्सा की ओर

  License

Creative Commons Attribution 4.0 and The Open Definition

 Abstract

The United States (U.S) financial system is an integral part of the efficient operation of the U.S. economy. During the current COVID-19 pandemic, the Federal Reserve had to take aggressive steps to protect the U.S. financial system. As a result, new financial transactions, including debt securities, corporate loans, advances and guarantees, common stock or equity, and derivative securities such as options and futures contracts, were executed. This article focuses explicitly on U.S. transfer pricing analysis regarding financial guarantee transactions.

Licence: creative commons attribution 4.0

  License

Creative Commons Attribution 4.0 and The Open Definition

 Keywords

Financial System, Economy, Covid-19

  License

Creative Commons Attribution 4.0 and The Open Definition

 Abstract

Licence: creative commons attribution 4.0

  License

Creative Commons Attribution 4.0 and The Open Definition

 Keywords

Retail Industry, Perceived Service Quality, Factor Analysis, Organized Retail

  License

Creative Commons Attribution 4.0 and The Open Definition

 Abstract

Licence: creative commons attribution 4.0

  License

Creative Commons Attribution 4.0 and The Open Definition

 Keywords

KEYWORDS: Knowledge Management, Benefits, Strategies, Socio- Cultural factors.

  License

Creative Commons Attribution 4.0 and The Open Definition

 Abstract

Licence: creative commons attribution 4.0

  License

Creative Commons Attribution 4.0 and The Open Definition

 Keywords

SARS-CoV-2, COVID-19, fat-soluble vitamins, micronutrients, immune response.

  License

Creative Commons Attribution 4.0 and The Open Definition