Volume 9 | Issue 6 |

 Abstract

Antibody therapeutics and vaccines are among our pis aller to finish the raging COVID-19 pandemic. They, however, are susceptible to over 5000 mutations on the spike (S) protein uncovered by a Mutation Tracker supported over 200?000 genome isolates. Recent variants of the virus within the UK, South Africa, and Brazil seem to spread more easily, which have the potential to steer to more hospitalizations and deaths. RNA sequence analysis of emerging SARS-CoV-2 infection is effective for tracking viral evolution and developing novel diagnostic tools. Furthermore, SARS-CoV-2 sequence analysis can provide insight into potential antigenic drift events that cause strain speciation and changing clinical outcomes. The tactic is definitely adaptable to research potential mutations of the virus, ensuring the simplest possible vaccines are quickly identified. This will give humans a big advantage over evolving mutations, with the model accomplishing vaccine design cycles that when took months or years during a matter of seconds or minutes. This text is an effort to predict mutations of novel coronavirus by applying machine learning techniques over bioinformatics.

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Creative Commons Attribution 4.0 and The Open Definition

 Keywords

COVID-19, Machine Learning, Sequential Pattern Mining, Corpus, Genome.

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Creative Commons Attribution 4.0 and The Open Definition

 Abstract

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Creative Commons Attribution 4.0 and The Open Definition

 Keywords

Internet of Things (IoT), Mobile application, Mobile sites, E-books, Social Media, Online Marketing, E-Commerce, women entrepreneurship

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Creative Commons Attribution 4.0 and The Open Definition

 Abstract

Examining air quality has become one of the most essential activities for the peoples in many industrial and urban areas today. The quality of air is adversely affected due to various forms of pollution caused by electricity, transportation, fuel uses etc. The deposition of harmful gases is creating a serious problem for the quality of life in smart cities. With this increasing air pollution, we need to implement efficient air quality monitoring and prdiction models which collect information about the concentration of air pollutants and provide assessment of air pollution in area. Particulate matter contains microscopic solids or liquid droplets that are so small that they can be inhaled and cause serious health problems. Of these, particles less than 2.5 micrometres in diameter, also known as fine particles or PM2.5, pose the greatest risk to health. Hence, air quality evaluation and prediction has become an important research area. The focus of this project is to study about the data mining and machine learning techniques used for prediction of air pollution and the mainly focus is on the prediction of PM2.5 on the basis of all the other air pollutants and temperature and humidity.

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Creative Commons Attribution 4.0 and The Open Definition

 Keywords

Air quality, PM 2.5, Prediction

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Creative Commons Attribution 4.0 and The Open Definition

 Abstract

This study has been undertaken to investigate the stress concentration capacity of different bolt arrangements in chord member of the built up K-joint. Chord member with three bolt arrangements are analysed using ANSYS 16.0. The behavior of 10 bolts arrangements including zigzag, arch shape, X-shape configurations under incremental loading was analysed using ANSYS 16.0. Here three models of bolt arrangements are introduced. This paper aims to obtain proper ranges for the geometric design parameters such as pitch, spacing for different bolt arrangements. In this order, 3 bolt connection were tested to evaluate the performance connections, and then a parametric study was carried out using the verified numerical models

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Creative Commons Attribution 4.0 and The Open Definition

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Bolt, loading, stress

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Creative Commons Attribution 4.0 and The Open Definition

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The static simulation is conducted on a crankshaft from a single cylinder 4- stroke diesel engine. A three-dimension model of diesel engine crankshaft is created using CATIA V5 software Static structural analysis is performed to obtain the stress magnitude at critic allocations of crankshaft in. The static analysis is done using Software ANSYS 2021R1 which resulted in the stresses, deformation and elastic strain. Boundary conditions are applied at bearings.Crankshafts find many applications in various branches of engineering. They are used whenever there is the need to translate reciprocating linear motion into rotation or vice-versa.In their more varied configurations, crankshafts are usually used in internal combustion engines but also in piston steam engines. It lays on the former the vaster and varied range of applications of crankshafts. The internal combustion engines cover various fields of uses, from small scale model planes to large maritime engines.

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 Keywords

Crankshaft,Composite Materials,Al7075,SiC,Catia,Ansys

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Creative Commons Attribution 4.0 and The Open Definition

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The article discusses in detail the concept of juvenile delinquency. A child is not a criminal from the womb of his mother but he is forced to become one due to various factors during his life. This article enlists such factors that lead a child to become delinquent. It is in the interest of society to prevent and eliminate juvenile delinquencies because such activities not only impact the juvenile himself but also the victim, his families, community and society. A society needs to be peaceful and safe for people for their overall growth and development and incidents of juvenile delinquencies become hurdle in the normal and smooth functioning of a society.

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 Keywords

Juvenile, Criminal, Sexual, Delinquency, Education

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Creative Commons Attribution 4.0 and The Open Definition

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The paper aims to document the historic events of the immediate years before and after India attained its freedom in 1947, as perceived by Indian sculptors of that period. The subject matters adopted by these sculptors were directly or indirectly influenced by the political environment of the times discussed. While some of the sculptors and their work discussed in this paper revolves around the general idea of freedom, while others chose to portray the sentiment of nationalism, patriotism, and nation building. The independence of India was earned at a cost. The partition of India left an everlasting and traumatic impression on many of the sculptors who were displaced. The paper also highlights how as compared to painting, the reflection of the historical events that predate and follow the independence of India through sculptures is relatively less.

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Nationalism, Independence, Partition, Expression, Sculpture.

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Creative Commons Attribution 4.0 and The Open Definition

 Abstract

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Creative Commons Attribution 4.0 and The Open Definition

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Key Words: Constitutional Amendment, Urban LUrban Local Bodies (ULBs), Decentralization, Urban Finances, Planning Committees.

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Creative Commons Attribution 4.0 and The Open Definition

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Abstract: Erectile dysfunction (ED) is a common disorder that is associated with the aging process, as well as a number of risk factors, such as high blood pressure, heart disease, obesity, dyslipidemia, diabetes, drug - related male hypogonadism, and pelvic surgery. Many of these factors are components of the metabolic syndrome, a major risk factor for cardiovascular disease (CVD). ED shares common risk factors for heart disease. Endothelial dysfunction seems to be the beginning of the underlying pathophysiology of these conditions. The efficacy, tolerability, and the cardiovascular safety of sildenafil were evaluated in many large, randomized, placebo-controlled clinical trials in the general population of men with erectile dysfunction, including men with a variety of medical conditions. This medicine is also effective in a variety of specific patient populations, including in difficult-to-treat populations such as diabetes mellitus and after radical prostatectomy. This is due to the rapid start-up of the action, within a 14-minute. some of the men - and it is a long-term period of up to 12 hours. Does this medicine is to improve the quality of life and satisfaction ?????????? male, and was well-tolerated with a favorable safety profile. New evidence suggests that sildenafil has beneficial effects on many chronic diseases. It has been approved for the treatment of idiopathic pulmonary hypertension. Numerous papers have proposed the same time, improves endothelial function, and suggested a potential role in premature ejaculation, or for the treatment of lower urinary tract symptoms.

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Creative Commons Attribution 4.0 and The Open Definition

 Keywords

erectile dysfunction, phosphodiesterase inhibitors, safety, treatment outcome

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Creative Commons Attribution 4.0 and The Open Definition

 Abstract

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Creative Commons Attribution 4.0 and The Open Definition

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Generation Z, Indian Marketers, Social media platforms

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Creative Commons Attribution 4.0 and The Open Definition