Volume 8 | Issue 6 |

 Abstract

A simple, rapid, selective, sensitive, accurate and precise High Performance Liquid Chromatography (HPLC) with UV detection method has been developed and validated for determination of Posaconazole in Human plasma. C18 (250x4.6mm) column was used with the mobile phase containing a mixture of Acetonitrile: Water (55:45v/v). The flow rate was 0.8ml/min and drug was monitored at 262nm. In analytical method development linearity for Posaconazole was found to be 5-100�g/ml with regression coefficient 0.9954. The accuracy and recovery was found within limit. The robustness study was performed and the method was found to be fully robust. Plasma samples were processed using acetonitrile as precipitating agent to extract drug. The linearity for Posaconazole was found to be 0.15 to 50?g/ml with regression coefficient (r2) 0.9955. The recovery was found to be 85.63%. Stability studies for freeze thaw cycle, short term stability and long term stability was done. The % CV for stability study was found within a limit.

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 Keywords

Posocanazole, Reverse phases HPLC, Accuracy, Precision,

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Creative Commons Attribution 4.0 and The Open Definition

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We know that a small fire in the forest eventually might lead to a forest fire in recent days we have seen many widely spread forest fires which might put wildlife in danger. Even in cities, in some industries where there is a possibility of a fire outbreak. So we propose an idea of monitoring the defined area using an aerial vehicle, i.e., a drone. If we use a drone equipped with low-cost cameras, memories, and suitable processing capabilities, it might be helpful in detecting the fire beforehand. Some of the remote sensing techniques can be used for providing much more accuracy in identifying the fire Image contains forest fires in real-time.

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UAV, RPV, GPS, IC, CSI

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Creative Commons Attribution 4.0 and The Open Definition

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Corporate social responsibility allows a business to fulfill their duties and responsibilities towards the society. It makes the company accountable not only to the shareholder but to the society as a large. Only to generate the revenue should not the objective of the corporate but it needs to think about the surrounding also for the long term survival. In April 2014, India became the first country to legally magnate corporate social responsibility. Many big and small corporate in India took the initiative and done excellent contribution to serve the nation. This paper focuses on the CSR activities of top companies who received the First national corporate award in the excellence of CSR in 2019 in the first three Categories

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 Keywords

Corporate Social Responsibility, inclusive growth ,sustainable development

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Creative Commons Attribution 4.0 and The Open Definition

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Students, the future of our nation and the agents of change in our societies, are flourishing and thriving in the educational institutions. They progress through a series of institutions facing changes time to time and year to year in schools, classes, teachers, peers, environment and activities. These changes may either help in developing abilities and skills to deal with the demanding situations and standards or vex or trouble them. Failure to negotiating these challenges can lead to stress and anxiety issues, retardation in educational achievements, school refusal or dropout. The aim of the present article is to determine the level of examination anxiety and academic achievement of secondary school students and to study examination anxiety in context to their academic achievement. A sample of 200 students was selected by random sampling technique from 10 Govt. and Private Secondary schools of Bhagalpur city in Bihar state. Pie diagram was plotted for graphic representation and F-value was calculated for one way analysis of variance. This study reveals that there is significant difference in examination anxiety of students of different academic achievement levels.

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 Keywords

Secondary school students, Examination Anxiety, Academic achievement

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Creative Commons Attribution 4.0 and The Open Definition

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Water is an essential innate resource on earth. All life including human being depends on water. Water resources are of great significance to human life and wealth and are the main insistence for the demand of drinking water, for irrigation of lands and industries. However, the pollution of the sampling area in this research is mainly from domestic pollution, which consists of some fixed pollutants, and the initial concentration of the pollutant does not fluctuate significantly. In practical applications, diverse pollution occurs, such as urban non-point source pollution, irrigation backwater pollution, livestock breeding pollution and garbage pollution. Water quality index uses variables such as dissolved oxygen, biochemical oxygen demand, acidity, alkalinity, chemical oxygen demand and chloride content, the index similarity are used to assess the water quality conditions.

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 Keywords

water quality index, dissolved oxygen, BOD, water pollution, water quality managemen

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Creative Commons Attribution 4.0 and The Open Definition

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Aquasomes are one of the most recently developed delivery mechanism to different sites for bioactive molecules such as peptides, proteins, hormones, antigens, and genes. Aquasomes are circular, with particle size of 60300 nm. Aquasomes are spherical particles formed from calcium phosphate or ceramic diamond coated with a polyhydroxy oligomeric film and acting as a network of nanoparticulate carriers, but rather than a pure nanoparticle. There are three layers of self-assembled structures consisting of a solid phase nanocrystalline core coated with oligomeric film adsorbing biochemically active molecules with or without modification... It is commonly used in implant preparation. Aquasomes used as RBC replacements, vaccines for viral antigen delivery and as a targeted method for intracellular gene therapy. The behavior and responsiveness of enzymes to molecular conformation made aquasomes a novel carrier of enzymes such as DNAs and pigments. This article discusses the concepts of self-assembly, the difficulties of preserving pairs of immobilized surfaces with both conformational integrity and biochemical operation. Successfully the delivery system was used to distribute insulin, hemoglobin, and enzymes such as serrati peptidase etc.

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Nanoparticulate, Nanocrystalline

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Creative Commons Attribution 4.0 and The Open Definition

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nspite of many efforts taken nowadays still security threats can be seen everywhere. And from the starting we are using just single level password authentication factors, which is not sufficient to give more security. In order to be more secure we can think of Three Level Password Authentication System. So this is an idea to implement three levels password authentication for true users. In short we can say, this is to implement three level of security. The First level password constitutes of simple text based password and this effort is taken to resist shoulder surfing attack through the text password. The Color Combination password there is basically three colors red green blue(RGB) where user can set different combination of colors according to there choice just by clicking on those colors forms the second level of authentication. Third level uses a Picture Password there at first user have to select an image in jpg format to use as an password and then user can set the password by clicking on the image in different places.These three levels of password in securing the resources from unauthorized use.

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 Keywords

Shoulder surfing, Grapical Authentication, Text based authentication

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Creative Commons Attribution 4.0 and The Open Definition

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The aim is to study the Interrelationship between financial markets for which the S&P BSE Bond index and the S&P BSE 100 index are used. Using the time series data of these index of the Indian bond and stock market ,the study employs various statistical and econometric tools to analyse the relationship between these two markets and concludes with a regression model explaining the relationship between bonds, stocks and gold to understand the extent to which gold is used as a substitute investment. Finally, the study concludes with bringing out the relationship between gold, stocks and bonds. The reason why gold is used in this analysis is because it is widely viewed as a haven investment when other assets fail.

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Interrelationship ,S&P BSE 100 index,S&P BSE Bond index,Indian bond and stock market, gold is used as a substitute investment

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Creative Commons Attribution 4.0 and The Open Definition

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Abstract Music is a universal language that transcends linguistic as well as cultural boundaries. It is a fundamental constituent of every culture. As such, it is a universal characteristic of human experience. Music preferences differ from person to person. These individual preferences reveal a great deal about the personality of an individual. Personality refers to the unique set of traits or characteristics that constitute an individual�s distinctive character. It encompasses an individual�s attitudes, habits, traits and the like which distinguishes him or her in relation to others. The aim of the present study was to examine the relationship between the Big Five personality traits i.e., Extraversion, Agreeableness, Conscientiousness, Emotional stability, Openness to experience and five dimensions of music namely Mellow, Unpretentious, Sophisticated, Intense and Contemporary put forward by Rentfrow, Goldberg & Levitin (2011). In order to achieve this objective a survey was carried out among 100 participants belonging to the age group of 18 to 28, of which 63 were female and 37 were male. Ten Item Personality Inventory (TIPI) and Short Test of Musical Preferences Revised (STOMP-R) were used to measure personality and music preference respectively. The sampling technique used was convenient sampling. In order to determine the association between the music and personality variables, Pearson �r� was calculated using SPSS. The findings revealed that Sophisticated dimension positively correlated to all five personality traits. The dimension called Mellow was found to be positively related to all the personality traits except emotional stability. The Unpretentious and Contemporary dimensions revealed positive correlations with extraversion, conscientiousness and openness but negative correlations with agreeableness and emotional stability. The last dimension, i.e., Intense was positively correlated to extraversion and openness but negatively correlated to agreeableness, conscientiousness and emotional stability. The implications, limitations and future directions have also been discussed in the paper.

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Creative Commons Attribution 4.0 and The Open Definition

 Keywords

Music preference, personality, Big Five.

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Creative Commons Attribution 4.0 and The Open Definition

 Abstract

The Indian economy is basically a mixed economy and its characterised as a developing market economy. It is the world's fifth-largest economy by nominal GDP and the third-largest by purchasing power parity. According to the IMF, on a per capita income basis, India ranked 139th by GDP and 118th by GDP in 2018. The sudden outbreak of the Covid-19 pandemic is an unpredictable shock to the Indian Economy. When we look upon the pre economy of India it was struck with decreasing rates of growth. With the prolonged country wide lockdown into several phases from March to June, the global economic downturn and it disrupted the demand and supply chain. The economy is likely to face the prolonged slowdown in the upcoming few years. In this paper we are going the discuss the various impacts of Covid-19 particularly on the Indian economy .

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Creative Commons Attribution 4.0 and The Open Definition

 Keywords

Covid-19 pandemic, impact on various sectors, Economic slowdown, economic package, economic recovery

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Creative Commons Attribution 4.0 and The Open Definition