IJCRT Peer-Reviewed (Refereed) Journal as Per New UGC Rules.
ISSN Approved Journal No: 2320-2882 | Impact factor: 7.97 | ESTD Year: 2013
Scholarly open access journals, Peer-reviewed, and Refereed Journals, Impact factor 7.97 (Calculate by google scholar and Semantic Scholar | AI-Powered Research Tool) , Multidisciplinary, Monthly, Indexing in all major database & Metadata, Citation Generator, Digital Object Identifier(CrossRef DOI)
IJCRT Journal front page | IJCRT Journal Back Page |
Paper Title: BEHIND THE SUCCESS: WOMEN
Author Name(s): Amanpreet Kaur
Published Paper ID: - IJCRT2506036
Register Paper ID - 282758
Publisher Journal Name: IJPUBLICATION, IJCRT
DOI Member ID: 10.6084/m9.doi.one.IJCRT2506036 and DOI :
Author Country : Indian Author, India, 144205 , Dasuya, 144205 , | Research Area: Others area Published Paper URL: http://ijcrt.org/viewfull.php?&p_id=IJCRT2506036 Published Paper PDF: download.php?file=IJCRT2506036 Published Paper PDF: http://www.ijcrt.org/papers/IJCRT2506036.pdf
Title: BEHIND THE SUCCESS: WOMEN
DOI (Digital Object Identifier) :
Pubished in Volume: 13 | Issue: 6 | Year: June 2025
Publisher Name : IJCRT | www.ijcrt.org | ISSN : 2320-2882
Subject Area: Others area
Author type: Indian Author
Pubished in Volume: 13
Issue: 6
Pages: a356-a358
Year: June 2025
Downloads: 107
E-ISSN Number: 2320-2882
Women cannot be differentiated based on their roles; they are creators. Unfortunately, these creators often do not receive the recognition they deserve. When we talk about their roles, we must acknowledge that throughout life, progress is possible primarily because of women. Women can also be categorized based on the localities in which they live. For instance, women in rural areas are often seen solely as housewives, with their roles confined to nurturing families. This perspective reduces their potential for becoming independent, self-sufficient decision-makers. While they create the future by raising the next generation, they are not recognized as masters of their own destinies. Women have both social and economic roles that are essential for community development. They play a crucial part in rural industrialization by contributing their time, effort, and knowledge. Notably, women possess strong financial management skills; they know how to save, where to spend, and how much to allocate for each need. With women's support, men can make informed decisions at the right time and take calculated risks. Additionally, women often innovate by starting businesses that cater to local needs, such as handicrafts, organic farming, and food processing. This entrepreneurial spirit fosters economic growth and improves their communities. This research paper discusses the significant contributions of women to rural industrialization and emphasizes their essential role in creating sustainable development.
Licence: creative commons attribution 4.0
Keywords: Rural Industrialization, Economic Empowerment, Community Development, Entrepreneurship, Sustainable Development,
Paper Title: Formulation And Evaluation Of An HERBAL Gel Containing Calendula Officinalis And Aloe Vera Gel For Topical Application
Author Name(s): Bishal Singh, Nyas Chopade, Rahul Sawant, Shivprasad Katkar, Prashant Ghogare
Published Paper ID: - IJCRT2506035
Register Paper ID - 287924
Publisher Journal Name: IJPUBLICATION, IJCRT
DOI Member ID: 10.6084/m9.doi.one.IJCRT2506035 and DOI :
Author Country : Indian Author, India, 400053 , Mumbai, 400053 , | Research Area: Pharmacy All Published Paper URL: http://ijcrt.org/viewfull.php?&p_id=IJCRT2506035 Published Paper PDF: download.php?file=IJCRT2506035 Published Paper PDF: http://www.ijcrt.org/papers/IJCRT2506035.pdf
Title: FORMULATION AND EVALUATION OF AN HERBAL GEL CONTAINING CALENDULA OFFICINALIS AND ALOE VERA GEL FOR TOPICAL APPLICATION
DOI (Digital Object Identifier) :
Pubished in Volume: 13 | Issue: 6 | Year: June 2025
Publisher Name : IJCRT | www.ijcrt.org | ISSN : 2320-2882
Subject Area: Pharmacy All
Author type: Indian Author
Pubished in Volume: 13
Issue: 6
Pages: a332-a355
Year: June 2025
Downloads: 100
E-ISSN Number: 2320-2882
The last few years have witnessed a rapid increase in the popularity of herbal and natural cures, thus leading to growing interest in plant-based models for dermatological applications. This present investigation deals with the formulation and evaluation of a herbal topical gel containing extracts of the well-known plants Calendula officinalis and Aloe vera gel with anti-inflammatory, antimicrobial, antioxidant, and wound-healing properties. Thus, the prime objective was directed at developing stable and effective herbal gels for topical application to promote skin healing and enhance dermal health. The Aqueous extraction method was used to prepare the Calendula officinalis plant extract where else Aloe vera gel was freshly prepared using mature leaves. Using Carbopol 940 as the gelling agent and combining it with glycerin as a humectant, different formulations of gel types were done. The formulations prepared were then subjected to a physicochemical parameter evaluation regarding pH, spreadability, viscosity, homogeneity, extrudability, and skin irritation. Of all formulations tested, the optimized gel has shown interesting pH, close to skin pH, good spreadability, and high extrudability without visible signs of phase separation or microbial growth. In addition, in vitro antimicrobial activity was carried out using the well diffusion method against common skin pathogens such as Staphylococcus aureus and Escherichia coli, with zones of inhibition observed to be promising. No irritation or adverse reactions were reported.
Licence: creative commons attribution 4.0
Calendula Officinalis, Aloe vera, Topical Formulation, Wound Healing, Anti-inflammatory activity, Aqueous extraction,
Paper Title: A STUDY ON BRAND AWARENESS AND ITS IMPACT ON SALES
Author Name(s): Dr. A. Jayanthi, Jagadeeshwari R R
Published Paper ID: - IJCRT2506034
Register Paper ID - 287941
Publisher Journal Name: IJPUBLICATION, IJCRT
DOI Member ID: 10.6084/m9.doi.one.IJCRT2506034 and DOI :
Author Country : Indian Author, India, 641607 , tiruppur, 641607 , | Research Area: Management All Published Paper URL: http://ijcrt.org/viewfull.php?&p_id=IJCRT2506034 Published Paper PDF: download.php?file=IJCRT2506034 Published Paper PDF: http://www.ijcrt.org/papers/IJCRT2506034.pdf
Title: A STUDY ON BRAND AWARENESS AND ITS IMPACT ON SALES
DOI (Digital Object Identifier) :
Pubished in Volume: 13 | Issue: 6 | Year: June 2025
Publisher Name : IJCRT | www.ijcrt.org | ISSN : 2320-2882
Subject Area: Management All
Author type: Indian Author
Pubished in Volume: 13
Issue: 6
Pages: a326-a331
Year: June 2025
Downloads: 118
E-ISSN Number: 2320-2882
This study investigates the crucial relationship between brand awareness and its subsequent impact on sales performance. The research explores how varying levels of brand recognition familiarity and recall influence consumer purchasing decisions. A quantitative approach was employed utilizing surveys and sales data analysis to assess the correlation between brand awareness metrics and actual sales figures. The investigation focuses on examining consumer perceptions and brand associations. The research seeks to determine the extent to which increased brand awareness translates into tangible sales growth. Furthermore the study analyzes the effectiveness of different marketing strategies in building and sustaining brand awareness. The impact of digital marketing social media presence and traditional advertising methods are considered. The analysis identifies key drivers of brand awareness and their relative contribution to sales uplift. The findings reveal a significant positive correlation between heightened brand awareness and increased sales revenue. The results demonstrate that brands with greater visibility and positive consumer perception tend to achieve higher sales volumes. The research suggests that strategic investments in brand building activities are essential for achieving sustainable business growth. The study contributes to the understanding of brand equity and its financial implications. The research offers practical insights for marketers seeking to optimize their brand strategies and improve sales performance. The implications of the research extend to businesses of all sizes seeking to leverage brand awareness for competitive advantage. The study acknowledges limitations such as the specific industry focus and the reliance on survey data. Future research directions include exploring the long-term effects of brand awareness campaigns and the influence of brand reputation on consumer loyalty.
Licence: creative commons attribution 4.0
Brand awareness, Sales performance, Brand reputation, competitive advantage
Paper Title: Conservation of Ground Water Resources: Significance of Jal-Jeevan-Hariyali Mission (JJHM) in Kaimur District of Bihar
Author Name(s): Rahul Kumar Singh, Prof.(Dr.) Usha Singh
Published Paper ID: - IJCRT2506033
Register Paper ID - 288124
Publisher Journal Name: IJPUBLICATION, IJCRT
DOI Member ID: 10.6084/m9.doi.one.IJCRT2506033 and DOI : https://doi.org/10.56975/ijcrt.v13i6.288124
Author Country : Indian Author, India, 821109 , BHABUA, 821109 , | Research Area: Social Science All Published Paper URL: http://ijcrt.org/viewfull.php?&p_id=IJCRT2506033 Published Paper PDF: download.php?file=IJCRT2506033 Published Paper PDF: http://www.ijcrt.org/papers/IJCRT2506033.pdf
Title: CONSERVATION OF GROUND WATER RESOURCES: SIGNIFICANCE OF JAL-JEEVAN-HARIYALI MISSION (JJHM) IN KAIMUR DISTRICT OF BIHAR
DOI (Digital Object Identifier) : https://doi.org/10.56975/ijcrt.v13i6.288124
Pubished in Volume: 13 | Issue: 6 | Year: June 2025
Publisher Name : IJCRT | www.ijcrt.org | ISSN : 2320-2882
Subject Area: Social Science All
Author type: Indian Author
Pubished in Volume: 13
Issue: 6
Pages: a314-a325
Year: June 2025
Downloads: 134
E-ISSN Number: 2320-2882
Water is requisite for chow of life. It is a bounded resource. Human utilize both forms of water, Surface water and Groundwater. But groundwater resources are foremost for drinking water needs and agriculture in Bihar. The state government has carried out a multipurpose scheme JAL-JEEVAN-HARIYALI MISSION (JJHM) to nurture groundwater conservation in all districts of Bihar. This program has inspired schools to harvest rainwater within their outskirts in Kaimur district. Not only the new creation of water bodies but also the identification and rejuvenation of conventional water bodies; Wells, Ponds, Tanks and Ahar Pyne is going on and some water bodies have been completed in the study area. This mission has not been completed yet so work is going on. This approach will enhance the potential for groundwater recharge. This study is based on secondary data. These are sources; National Compilation on Dynamic Ground Water Resources of India, 2022 and JJHM Annual Report FY 2022-23. This scheme plays a remarkable role in assuring sustainable water management in Kaimur. by elevating rainwater harvesting and reviving conventional water sources, the Bihar government is working to conserve invaluable groundwater resources for future generations.
Licence: creative commons attribution 4.0
Groundwater Conservation, Groundwater Extraction, Groundwater Resource, JAL-JEEVAN-HARIYALI MISSION(JJHM), Rainwater Harvesting
Paper Title: NANOTECHNOLOGY IN MEDICINE: REVOLUTIONIZING DRUG DELIVERY AND DIAGNOSTICS
Author Name(s): D.Tanmaya Sai, Dr.L.Kiran Kumar Reddy
Published Paper ID: - IJCRT2506032
Register Paper ID - 285779
Publisher Journal Name: IJPUBLICATION, IJCRT
DOI Member ID: 10.6084/m9.doi.one.IJCRT2506032 and DOI :
Author Country : Indian Author, India, 500056 , secunderabad, 500056 , | Research Area: Science and Technology Published Paper URL: http://ijcrt.org/viewfull.php?&p_id=IJCRT2506032 Published Paper PDF: download.php?file=IJCRT2506032 Published Paper PDF: http://www.ijcrt.org/papers/IJCRT2506032.pdf
Title: NANOTECHNOLOGY IN MEDICINE: REVOLUTIONIZING DRUG DELIVERY AND DIAGNOSTICS
DOI (Digital Object Identifier) :
Pubished in Volume: 13 | Issue: 6 | Year: June 2025
Publisher Name : IJCRT | www.ijcrt.org | ISSN : 2320-2882
Subject Area: Science and Technology
Author type: Indian Author
Pubished in Volume: 13
Issue: 6
Pages: a302-a313
Year: June 2025
Downloads: 96
E-ISSN Number: 2320-2882
Nanotechnology is revolutionizing the field of medicine, offering innovative solutions for drug delivery, diagnostics, and treatment. By leveraging nanoscale materials and structures, researchers are developing highly targeted and efficient therapies that minimize side effects and enhance patient outcomes. Nanoparticles are being used to deliver drugs directly to diseased cells, improving the precision of treatments for conditions such as cancer, cardiovascular diseases, and neurodegenerative disorders. In diagnostics, nanotechnology enables early detection of diseases through advanced imaging techniques and biosensors with unparalleled sensitivity. This seminar explores the applications of nanotechnology in medicine, focusing on its role in personalized medicine, nanotheranostics (a combination of therapy and diagnostics), and the development of biocompatible nanomaterials. Additionally, it addresses the challenges of clinical translation, including regulatory hurdles, safety concerns, and scalability. By understanding these advancements, healthcare professionals, researchers, and policymakers can harness nanotechnology to shape the future of medicine and improve global health outcomes.
Licence: creative commons attribution 4.0
Nanomedicine, Targeted Drug Delivery, Diagnostic Nanoparticles, Biosensors, Personalized Medicine, Biomedical Nanotechnology ________________________
Paper Title: Uttarkhand ke sanskrutik lokachar ki prushbhumi me Dr. Ramesh Pokhriyal "nishank" ke gadhya sahitya mein mahilao ka pratinidhitva, netrutva evam sangharsh
Author Name(s): Hemlata Pokhriyal, Dr. Manisha Agrawal
Published Paper ID: - IJCRT2506031
Register Paper ID - 287655
Publisher Journal Name: IJPUBLICATION, IJCRT
DOI Member ID: 10.6084/m9.doi.one.IJCRT2506031 and DOI :
Author Country : Indian Author, India, - , -, - , | Research Area: Science and Technology Published Paper URL: http://ijcrt.org/viewfull.php?&p_id=IJCRT2506031 Published Paper PDF: download.php?file=IJCRT2506031 Published Paper PDF: http://www.ijcrt.org/papers/IJCRT2506031.pdf
Title: UTTARKHAND KE SANSKRUTIK LOKACHAR KI PRUSHBHUMI ME DR. RAMESH POKHRIYAL "NISHANK" KE GADHYA SAHITYA MEIN MAHILAO KA PRATINIDHITVA, NETRUTVA EVAM SANGHARSH
DOI (Digital Object Identifier) :
Pubished in Volume: 13 | Issue: 6 | Year: June 2025
Publisher Name : IJCRT | www.ijcrt.org | ISSN : 2320-2882
Subject Area: Science and Technology
Author type: Indian Author
Pubished in Volume: 13
Issue: 6
Pages: a288-a301
Year: June 2025
Downloads: 110
E-ISSN Number: 2320-2882
Uttarkhand ke sanskrutik lokachar ki prushbhumi me Dr. Ramesh Pokhriyal "nishank" ke gadhya sahitya mein mahilao ka pratinidhitva, netrutva evam sangharsh
Licence: creative commons attribution 4.0
Uttarkhand ke sanskrutik lokachar ki prushbhumi me Dr. Ramesh Pokhriyal "nishank" ke gadhya sahitya mein mahilao ka pratinidhitva, netrutva evam sangharsh
Paper Title: Redefining Eye Disease Detection: Deep Learning-Driven Identification of Cataract, Diabetic Retinopathy, and Glaucoma
Author Name(s): Harendra Yadav, Mr. Chiman Saini, Ms. Monika Saini
Published Paper ID: - IJCRT2506030
Register Paper ID - 288373
Publisher Journal Name: IJPUBLICATION, IJCRT
DOI Member ID: 10.6084/m9.doi.one.IJCRT2506030 and DOI :
Author Country : Indian Author, India, - , -, - , | Research Area: Science and Technology Published Paper URL: http://ijcrt.org/viewfull.php?&p_id=IJCRT2506030 Published Paper PDF: download.php?file=IJCRT2506030 Published Paper PDF: http://www.ijcrt.org/papers/IJCRT2506030.pdf
Title: REDEFINING EYE DISEASE DETECTION: DEEP LEARNING-DRIVEN IDENTIFICATION OF CATARACT, DIABETIC RETINOPATHY, AND GLAUCOMA
DOI (Digital Object Identifier) :
Pubished in Volume: 13 | Issue: 6 | Year: June 2025
Publisher Name : IJCRT | www.ijcrt.org | ISSN : 2320-2882
Subject Area: Science and Technology
Author type: Indian Author
Pubished in Volume: 13
Issue: 6
Pages: a272-a287
Year: June 2025
Downloads: 99
E-ISSN Number: 2320-2882
Addressing visual disorders--such as cataracts, retinal degeneration from diabetes, and elevated intraocular pressure--at their onset is key to avoiding irreversible sight damage in aging and high-risk populations. Deep learning, as an advanced subset of modern computational intelligence, has reshaped the landscape of automated medical diagnostics, particularly in ophthalmology. This report investigates its use in recognizing three prominent vision-related disorders--cataract, diabetic retinal complications, and glaucoma--by highlighting crucial factors such as algorithm design, data variability, and real-world clinical integration. Contemporary neural systems, including convolution-driven architectures and attention-based visual models, are employed to extract both structural and contextual details from retinal imagery like fundus scans, OCT outputs, and slit-lamp visuals. Despite their promise, these systems often struggle with the limited availability of high-quality, annotated data--commonly affected by class disparities or visual inconsistencies due to equipment differences. To enhance detection accuracy and generalization, practitioners utilize methods like domain-adapted transfer learning, synthetic augmentation, and precision-tuning based on ocular features. Furthermore, clinical implementation demands interpretable models, regulatory validation, and seamless integration with electronic health records. Real-world deployments in telemedicine platforms and mobile eye-care units have demonstrated the scalability and cost-effectiveness of AI-driven diagnostics, especially in resource-limited settings. By addressing both technical and clinical challenges, deep learning offers a promising pathway toward timely and accurate detection of vision-threatening conditions.
Licence: creative commons attribution 4.0
Redefining Eye Disease Detection: Deep Learning-Driven Identification of Cataract, Diabetic Retinopathy, and Glaucoma
Paper Title: Enhancing Solar Energy Forecasting Accuracy through Machine Learning and Deep Learning Techniques
Author Name(s): Tushar Arya, Ms. Anjali Dhamiwal, Ms. Monika Saini
Published Paper ID: - IJCRT2506029
Register Paper ID - 288372
Publisher Journal Name: IJPUBLICATION, IJCRT
DOI Member ID: 10.6084/m9.doi.one.IJCRT2506029 and DOI :
Author Country : Indian Author, India, - , -, - , | Research Area: Science and Technology Published Paper URL: http://ijcrt.org/viewfull.php?&p_id=IJCRT2506029 Published Paper PDF: download.php?file=IJCRT2506029 Published Paper PDF: http://www.ijcrt.org/papers/IJCRT2506029.pdf
Title: ENHANCING SOLAR ENERGY FORECASTING ACCURACY THROUGH MACHINE LEARNING AND DEEP LEARNING TECHNIQUES
DOI (Digital Object Identifier) :
Pubished in Volume: 13 | Issue: 6 | Year: June 2025
Publisher Name : IJCRT | www.ijcrt.org | ISSN : 2320-2882
Subject Area: Science and Technology
Author type: Indian Author
Pubished in Volume: 13
Issue: 6
Pages: a260-a271
Year: June 2025
Downloads: 98
E-ISSN Number: 2320-2882
The early identification of ocular diseases--namely cataract, diabetic retinopathy (DR), and glaucoma--is vital for preventing permanent vision loss, especially among elderly individuals and patients with diabetes. With the rising global prevalence of these conditions, there is an urgent need for scalable and accurate screening solutions. Over the past few years, deep learning has become a reliable approach for recognizing diseases by processing and interpreting medical images automatically. This report investigates the role of deep learning in the early diagnosis of cataract, DR, and glaucoma, focusing on critical aspects such as image acquisition, data preprocessing, model architecture, and clinical applicability. Modern AI architectures, like convolutional neural networks and vision transformers, have proven highly effective in examining intricate visual data from retinal and ocular scans. Moreover, the report discusses the challenges related to dataset variability, imbalance, and annotation, as well as the importance of explainability and validation in clinical environments. As the field progresses, the integration of deep learning-based tools into routine ophthalmic care holds the potential to enhance diagnostic accuracy, reduce workload for healthcare professionals, and improve outcomes for patients worldwide.
Licence: creative commons attribution 4.0
Enhancing Solar Energy Forecasting Accuracy through Machine Learning and Deep Learning Techniques
Paper Title: THE RISE OF ARTIFICIAL INTELLIGENCE IN CORPORATE ACCOUNTABILITY: LEGAL IMPLICATIONS FOR CORPORATE GOVERNANCE IN INDIA
Author Name(s): Bharath Prakash, Jyotirmoy Banerjee
Published Paper ID: - IJCRT2506028
Register Paper ID - 288286
Publisher Journal Name: IJPUBLICATION, IJCRT
DOI Member ID: 10.6084/m9.doi.one.IJCRT2506028 and DOI :
Author Country : Indian Author, India, - , -, - , | Research Area: Science and Technology Published Paper URL: http://ijcrt.org/viewfull.php?&p_id=IJCRT2506028 Published Paper PDF: download.php?file=IJCRT2506028 Published Paper PDF: http://www.ijcrt.org/papers/IJCRT2506028.pdf
Title: THE RISE OF ARTIFICIAL INTELLIGENCE IN CORPORATE ACCOUNTABILITY: LEGAL IMPLICATIONS FOR CORPORATE GOVERNANCE IN INDIA
DOI (Digital Object Identifier) :
Pubished in Volume: 13 | Issue: 6 | Year: June 2025
Publisher Name : IJCRT | www.ijcrt.org | ISSN : 2320-2882
Subject Area: Science and Technology
Author type: Indian Author
Pubished in Volume: 13
Issue: 6
Pages: a250-a259
Year: June 2025
Downloads: 137
E-ISSN Number: 2320-2882
The integration of Artificial Intelligence (AI) into corporate operations is rapidly transforming the landscape of corporate governance and accountability in India. As companies increasingly adopt AI-driven tools for decision-making, compliance, risk management, and internal audits, significant legal and ethical implications emerge. This paper explores how AI challenges traditional models of corporate governance and necessitates a rethinking of regulatory frameworks to ensure accountability, transparency, and fairness. In India, the Companies Act, 2013 and the evolving jurisprudence around corporate responsibility do not yet fully address the complexities introduced by autonomous and semi-autonomous AI systems. Key concerns include the delegation of decision-making to AI without clear accountability, biases in algorithmic processes, data privacy issues, and the risk of regulatory arbitrage. Furthermore, questions arise regarding liability attribution when AI errors lead to financial misreporting, discrimination, or regulatory non-compliance. This paper argues that while AI can enhance governance efficiency, it also complicates the assignment of responsibility, thereby demanding a more robust legal framework. It calls for the introduction of AI governance norms tailored to the Indian corporate context, including mandatory algorithmic audits, board-level tech literacy, and legal recognition of AI-assisted decision-making protocols. Additionally, the role of regulators such as SEBI and the Ministry of Corporate Affairs must evolve to address AI-specific challenges. Through case studies and comparative analysis with global practices, the paper highlights both the opportunities and regulatory gaps in India's current corporate governance regime. Ultimately, it seeks to propose a balanced approach that enables innovation while safeguarding accountability and public trust.
Licence: creative commons attribution 4.0
Artificial Intelligence, Corporate Governance, Legal Accountability, Indian Companies Act, Algorithmic Regulation
Paper Title: REVIEW ON SOLUBILITY ENHANCEMENT TECHNIQUE
Author Name(s): Shashikant Saini, Sunita Rani, Rohit Saini
Published Paper ID: - IJCRT2506027
Register Paper ID - 288229
Publisher Journal Name: IJPUBLICATION, IJCRT
DOI Member ID: 10.6084/m9.doi.one.IJCRT2506027 and DOI :
Author Country : Indian Author, India, 247464 , Roorkee, 247464 , | Research Area: Pharmacy All Published Paper URL: http://ijcrt.org/viewfull.php?&p_id=IJCRT2506027 Published Paper PDF: download.php?file=IJCRT2506027 Published Paper PDF: http://www.ijcrt.org/papers/IJCRT2506027.pdf
Title: REVIEW ON SOLUBILITY ENHANCEMENT TECHNIQUE
DOI (Digital Object Identifier) :
Pubished in Volume: 13 | Issue: 6 | Year: June 2025
Publisher Name : IJCRT | www.ijcrt.org | ISSN : 2320-2882
Subject Area: Pharmacy All
Author type: Indian Author
Pubished in Volume: 13
Issue: 6
Pages: a240-a249
Year: June 2025
Downloads: 104
E-ISSN Number: 2320-2882
The absorption process is developed in biological systems to deliver necessary organic and inorganic substances into systemic circulation while maintaining bioavailability. Bioavailability issues might be caused by insufficient solubility or permeability. Most chemicals have solubility difficulties. As a result, as chemical science advances, so does the necessity for the creation of pharmaceutical technologies, which vary depending on the medicine. The medicine has relatively low water solubility, which means that it dissolves slowly in the gastrointestinal tract. The oral route is the most desirable and preferred method of giving medicinal medicines because of their systemic effect. Drugs are categorized into four classes according on their solubility under the BCS classification. Various strategies are employed to increase the solubility of poorly soluble medications, including physical and chemical alterations of the drug, as well as additional methods such as particle size reduction, crystal engineering, salt creation, solid dispersion, surfactant application, and complexation. The choice of solubility-improving technology is determined by the drug's properties, absorption site, and dose form requirements.
Licence: creative commons attribution 4.0
KEY WORDS: Bioavailability, Novel methods, Solubility, BCS Class.