Volume 12 | Issue 6 |

 Abstract

Education is the most important parameter in everybody's life now-a-days. People from all the parts of India are here to learn and educated themselves as much as possible in their lives. Due to lack of sources and no proper guidance for learning many children are not able to study and learn. The problem of not getting better and higher education in the native place is also the cause of no opportunities to learn. Furthermore, the children from remote areas from state of Maharashtra, India are still struggling for better and higher education which causes the problem of migration to different states which is very hectic and non feasible. To cope with this problem, in this paper planning of special education zone (education hub) is done i.e all types of education institutes are brought in the same place i.e under one umbrella. The planning of the education hub in the Institutional zone was obtained by plotting of various colleges such as Ayurvedic Institute, Engineering Institute, Medical Institute, Law Institute, etc. with the help of AutoCAD software.

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Better and higher education, Maharashtra state children, Migration, Planning, Special education hub, AutoCAD.

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Refreshable Braille displays are an absolute necessity for the visually impaired individuals, offering tactile access to digital content through dynamic pin arrays that form Braille characters. These displays connect to computers and smartphones granting users access to a wide range of information and encouraging independence and inclusion in a digital world. While speech output suffices for many materials, electronic Braille displays are preferred for technical texts, despite their high cost and limited availability of translated books. To address these challenges, a novel device is proposed, featuring a single Braille cell design. The paper involves designing a compact hardware solution with solenoid-based tactile pins controlled by an Arduino microcontroller via a Bluetooth-enabled application. This innovative approach promises cost-effectiveness, efficiency, and compatibility with various digital devices, enhancing accessibility and independence for visually impaired individuals.

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Braille display, grade 1 Braille, solenoid, electromagnetic actuation, visually impaired.

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The paper aims to explore the concept of dread and desperation depicted by the character Werner Pfennig, a German boy in the novel All the Light We Cannot See written by Anthony Doerr. The novel depicts a tale of hope, resilience, and the human spirit during World War II. The plot follows two young protagonists, Marie-Laure, a blind French girl, and Werner, a German boy, whose paths intersect amid war. The novel explores existentialist themes through the characters' experiences and struggles. Werner, a 15-year-old German boy, grows up in a mining town, where he becomes fascinated with radio technology. He eventually gets recruited into the German army, where he is tasked with tracking down enemy radio signals. He is assigned to a task force charged with locating and destroying anti-German radio broadcasts. Werner is reluctant to join the army, but he has little choice in the matter. He is forced to participate in the war effort and his skills in radio technology make him an asset to the German army. The paper attempts to explore the concept of dread and desperation and highlights feelings of disconnection, confusion, and search for meaning by Werner in the novel.

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Aim: To assess the impact of taking proper breaks while working on digital devices in reducing the digital eye strain. Methodology: This was a questionnaire-based prospective study determining the role of taking proper breaks and the role of daily reminders in enhancing patient compliance and in-turn reducing digital eye strains. The study examines compliance variations with the 20-20 rule in two distinct groups, Group-I (Subjects who got daily reminders) and Group-II (Subjects who did not get any reminders). The occurrence of symptoms related to digital eye strains were also compared between the subjects in the two groups and from baseline. Result: The analysis reveals that Group-II exhibits a notably higher forgetfulness rate (60%) compared to Group-I (28%), implying a greater tendency to overlook the 20-20 rule. This discrepancy underscores the potential influence of awareness on adherence, as Group-I's lower forgetfulness rate suggests heightened attentiveness to the rule. Conclusion: A significant proportion of respondents were not aware of the 20-20 rule and do not actively implement it. Making the patients aware about proper visual break practices can significantly reduce digital eye strain prevalence. From the data, it seems that both Group-1 and Group-2 generally have lower symptom prevalence compared to the Baseline group. However, Group-2 tends to have higher symptom prevalence compared to Group-1 indicating that reminders may play an important role in reduction in symptoms of digital eye strain. The data suggests a discrepancy in compliance with the 20-20 rule between the two groups, highlighting the importance of reminders in getting better compliance. Practically, these results could inform targeted interventions, focusing on raising awareness among Group-II individuals to mitigate forgetfulness.

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Digital Eye Strain, Computer Vision Syndrome, Dry Eyes, 20-20 Rule, Visual Breaks

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This report is based onmy work in the Central Laboratory of Sharda Hospital. The main discussion here is about techniques and procedures that are usually opted for diagnosis and identification of pathogens and disease causing agents, which can be useful for the purpose of research also. Broadly divided into Biochemistry, Microbiology (Bacteriology, Serology ,Virology and Mycology) and Pathology. In Biochemistry techniques such as Chromatography and its types including - Thin-layer chromatography (TLC), Column chromatography and High-performance liquid chromatography (HPLC) as well as basics of Spectroscopy UV-Visible spectroscopy, Infrared spectroscopy (IR) and Fluorescence spectroscopy. Mass Spectrometry and Enzyme Assays along with Protein purification techniques such as Affinity chromatography, Size-exclusion chromatography , NMR (Nuclear Magnetic Resonance) spectroscopy and Bioinformatics. In Microbiology methods and techniques in Bacteriology mainly focused on culturing Bacteria and processing them through different staining methods, biochemical testing and smear preparation. Serology Lab mainly use strip testing (The kit contains indicators to visualize the reaction between antibodies and reagents. This could involve color changes, fluorescence, or other methods depending on the design of the kit). Virology and Molecular Laboratory employs techniques such as ELISA, RT-PCR and methods for DNA extraction. Working in Pathology Lab teaches us about Histopathology(This involves the microscopic examination of tissue samples to study the cellular structure and identify any abnormalities. Tissues are typically stained with dyes to enhance visualization), Cytology, Immunohistochemistry (IHC) and Clinical Chemistry, techniques include spectrophotometry, chromatography, and immunoassays. Along with Flow Cytometry used for Hematological analysis to evaluate blood samples to assess the cellular components (red blood cells, white blood cells, and platelets) and their characteristics. Other techniques include complete blood count (CBC), blood smear examination, and coagulation assays.

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RtPCR, Immunoassay , Microscopy

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Hyperandrogenism and persistent anovulation are two characteristics of the complex condition known as polycystic ovarian syndrome(PCOS).6% to 20% of women in their reproductive years may be impacted, depending on the diagnostic criteria. Early in the pubertal years is when PCOS symptoms first appear. Period irregularities, anovulation, and acne are features of both PCOS and normal female pubertal development. Because of the intricately entwined pathophysiology, identifying the causative factors is difficult. Most clinical data that are now accessible include findings and results for adult females. Different diagnostic criteria have been established for PCOS in teenage girls, while the Rotterdam criteria are recognized for adult women. Menstrual irregularity ,clinical hyperandrogenism, and/or hyper androgenemia are diagnostic features for teenage girls. It is not necessary to use the results of a pelvic ultrasound to diagnose PCOS in teenage girls. Teenagers exhibiting the clinical indicators of androgen excess and oligomenorrhoea/amenorrhoea-two characteristics of PCOS-can be considered" at risk for PCOS" even in the absence of a formal diagnosis. Education, measures promoting a healthy lifestyle, and therapy aimed at symptom relief are all part of the management of PCOS, for both individuals at risk and those with a diagnosis that has been established. Metformin, combination oral contraceptive pills, spironolactone, and topical therapies for acne and hirsutism are examples of interventions. Management should involve planned transitions to adult care providers and routine follow-up visits in addition to screening for related comorbidities. A thorough understanding of the pathophysiology of PCOS will allow for the early detection of girls who are highly predisposed to the disease. Appropriate therapy interventions when implemented on time will enhance quality of life, reduce related comorbidities, and improve overall management of PCOS during adolescence.

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Polycystic ovary syndrome; hyperandrogenism; insulin resistance; Metformin; anovulation; Metabolic Disorders ;Medicinal Plants

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Cancers are caused bycombined genetic and non-genetic changes induced by environmental factors that trigger inappropriate activation or inactivation of specificgenes leading to neoplastic transformations, or abnormal cell growth. The compound ware synthesized and found to be pure.Their melting points were taken and will be sent for analysis followed by activity. The following work will be under taken: Characterization of this compound by NMR, Mass, IR and biological activity -invitro cell line screening on MCF-7 (human breast cancer cell line), HeLa (human cervical cancer cell line), SKMEL-2 (human melanoma cancer cell line) and HL-60 (human leukemia cancer cell line).will be carried out after synthesized and Characterization of compound.

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Cancer, Cancer growth, Pyrazole, Docking study.

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As a means to resolve the Tribal Voice in India, the centrality of the Fifth and Sixth Schedules of the Indian Constitution is widely acknowledged. However, their final incorporation, despite intense nationalist opposition in the run-up to Indian Independence, remains historically unexplained. This article addresses this lacuna by reconstructing the circumstances under which the Indian National Congress came to accept scheduling as a viable method of providing protection to Tribal Communities. This strategic shift can be explained as a result of combined political pressures generated by communist-led tribal movements and a steadily mounting challenge heralded by a new stream of educated middle-class tribal activists in eastern India. Foremost among the latter was Jaipal Singh Munda who mobilized a large constituency of supporters demanding a separate province of Jharkhand. Taken together, there is enough evidence to prove that in the period 1937-1950, the tribes were not silent and their collective agency had a deep impact on the constitution-making process. Finally, the article argues that this period witnessed a significant change in the character of the Congress as erstwhile freedom-fighters turned into ruling elites.

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Constituent Assembly, Fifth Schedule, Constitution, Tribal Rights, Dignity, Welfare, Adivasi Mahasabha, Protection to Indigenous.

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This study aims to explore and compare the investment habits of Generation Y (born roughly between 1980 and 1997) and Generation Z (born between 1997 and 2010). The research employs a mixed-method approach, incorporating quantitative surveys and qualitative interviews to gather comprehensive data. Factors such as risk tolerance, investment knowledge, preferred investment vehicles, and attitudes towards financial planning will be examined. The findings will provide insights into the distinct preferences and behaviors of each generation regarding investment practices, aiding financial institutions and policymakers in tailoring strategies to effectively engage and serve these demographic groups.

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Investment Habits, Gen Y, Gen Z, Comparitive, Millenials, Tradition, Modern, Shares, gold, real estate

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Soaps are essential for maintaining our hygiene and health because they eliminate dirt from the body in addition to having bactericidal properties. Our study's objective was to create herbal soap using the melt-and-pour technique. The purpose of this research is to create an antibacterial polyherbal bath soap using some of the antibacterial qualities of herbal plant extracts. In this review, we looked at the various herbal plants that are used to make soap that has antibacterial, antifungal, and antibacterial properties. Many naturally occurring herbal plants contain a range of chemical components that are used in cosmetic preparations. Because they have a high activity level and no negative effects, herbal cosmetics are particularly significant. Fungi is the most common type of skin infection in humans, and it requires special care to keep the skin healthy and to heal. A specific type of soap called soap is used to treat different fungal infections. Both conventional herbal remedies, such as plant extracts or herbal oils, and allopathic medications can be used to treat these infections. It aids with acne and pimple prevention, skin brightening, softening, and smoothing, and skin polishing, replenishing, and rejuvenation. In this review, we looked at various herbal plants that have antifungal, antibacterial, and antimicrobial properties, including turmeric, guava, banana, and mango leaves, as well as Aloe Vera and Tulsi. Because of their antibacterial and antifungal properties, all of these herbal remedies are highly regarded and well-known in Ayurveda. People are most commonly affected by fungal skin infections, which need careful attention both during treatment and in order to maintain healthy skin. On Candida albicans, Azadiracta indica, Aloe berbadendis, Curcuma longa, and Ocimum sanctum exhibit activity. Soap NoHerbal helps to address fungal skin infection issues. Antibacterial soaps clearly contain antibacterial agents that have the ability to either kill or inhibit bacteria. The majority of commercial soaps include ingredients that may be bad for your skin. It was determined what the formulations' physicochemical parameters were (pH, foaming ability, stability, and physical evaluation). The formulation had an excellent foaming index and a pH level that was almost identical to that of skin, according to the results.

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Herbal soap, Melt and pour technique, antifungal, antibacterial, antimicrobial, TFM, , guava leaf, banana leaf, mango leaf, anti-inflammatory, etc.

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