Volume 11 | Issue 6 |

 Abstract

The description, characterization and quantisation of the identified and unidentified impurities present in new drug substances is known as impurity profile. Impurity is defined as any substance coexisting with the original drug, such as starting material or intermediates or that is formed, due to any side reactions. Impurity can be of three types: Impurities closely related to the product and coming from the chemical or from the biosynthetic route itself, Impurities formed due to spontaneous decomposition of the drug during the storage or on exposure to extreme conditions, or the precursors which may be present in the final product as impurities. The suggested structures of the impurities can be synthesized and will provide the final evidence for their structures, previously determined by spectroscopic methods. Therefore it is essential to know the structure of these impurities in the bulk drug in order to alter the reaction condition and to reduce the quantity of impurity to an acceptable level. Isolation, identification and quantification of impurities help us in various ways, to obtain a pure substance with less toxicity and, safety in drug therapy.

Licence: creative commons attribution 4.0

  License

Creative Commons Attribution 4.0 and The Open Definition

 Keywords

cefotaxime ofheavy multi-component diacetylatedparacetamol

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Creative Commons Attribution 4.0 and The Open Definition

 Abstract

Hospital wastes pose a significant impact on health and environment. It spred the environmental polution and affect the health of human and animal. So study of bio-medical Weste is very important.

Licence: creative commons attribution 4.0

  License

Creative Commons Attribution 4.0 and The Open Definition

 Keywords

Immunization pathological waste microbiology culture

  License

Creative Commons Attribution 4.0 and The Open Definition