Volume 9 | Issue 5 |

 Abstract

Sustained release matrix tablets facilitate prolonged and continuous drug release and improve the bioavailability of drugs while avoiding unwanted side effects. The goal in designing sustained or controlled delivery systems is to reduce frequency of dosing or to increase the effectiveness of the drug by localization at the site of action, reducing the dose required, providing uniform drug delivery. Sustained release drug administration means not only prolongation of duration of drug delivery, but the term also implies the predictability and reproducibility of drug release kinetics. The controlled release of drug substances and their effective transport to sites of action can be exploited to maximize the beneficial clinical response and to minimize the incidence of unbeneficial adverse reactions and side effects. Oral ingestion has long been the most convenient and commonly employed route of drug delivery. Indeed, for sustained release systems, oral route of administration has received most of the attention with respect to research on physiological and drug constraints as well as design and testing of products.

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Creative Commons Attribution 4.0 and The Open Definition

 Keywords

Sustained release, matrix tablets, bioavailability, side effects

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Creative Commons Attribution 4.0 and The Open Definition

 Abstract

Recently, extended release pharmaceutical products became a very useful tool in medical practice, offering a wide range of actual and perceived advantages to the patients. Oral drug delivery is the most preferred route for the various drug molecules among all other routes of drug delivery, because ease of administration which lead to better patient compliance. So, oral extended release drug delivery system becomes a very promising approach for those drugs that are given orally but having the shorter half-life and high dosing frequency. Extended release is also providing promising way to decrease the side effect of drug by preventing the fluctuation of the therapeutic concentration of the drug in the body. Oral extended release drug delivery medication will continue to account for the largest share of drug delivery systems. The extended release product will optimize therapeutic effect and safety of a drug at the same time improving the patient convenience and compliance. Recent trends indicate that multiparticulate drug delivery systems are especially suitable for achieving extended release oral formulations with low risk of dose dumping, flexibility of blending to attain different release patterns as well as reproducible and short gastric residence time. The release of drug from pellets depends on a variety of factors including the carrier used to form pellets and the amount of drug contained in them. Consequently, pellets provide tremendous opportunities for designing new controlled and extended release oral formulations, thus extending the frontier of future pharmaceutical development.

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Creative Commons Attribution 4.0 and The Open Definition

 Keywords

Extended Release, Oral route, Therapeutic concentration, Pellet, Dosage form

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Creative Commons Attribution 4.0 and The Open Definition

 Abstract

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Creative Commons Attribution 4.0 and The Open Definition

 Keywords

stressor, stress level, coping, nursing students, nursing college

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Creative Commons Attribution 4.0 and The Open Definition

 Abstract

Abstract- This study designed to explore the prevalence of role conflict among the nurses who is working in multispecialty medical college hospitals of Dakshina Kannada district in Karnataka state. There is necessitate to emphasize the difficulty of nurses who occupy yourself in providing better healthcare to the society. 500 respondents selected through simple random technique and the result showed that the majority of nurses had moderate level of role conflict (72.2%). A incorporated logical structure of specific strategies are required to decrease their job stress and role conflict.

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Creative Commons Attribution 4.0 and The Open Definition

 Keywords

Nursing professionals, Role conflict

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Creative Commons Attribution 4.0 and The Open Definition

 Abstract

Homomorphic encryption (HE) is an encryption technique where operations are performed on ciphertext. This encryption method can be used in varieties of applications by using public key algorithms. For transferring data from one place to another, there are various encryption algorithms for storage of data and securing the operations, but they do not preserve privacy. HE is useful in various applications in which HE performs the different operations on encrypted data and provides results after calculations performed directly on the plaintext. Nowadays, security of information and calculations to deal with the data of big business has expanded massively. In any case, a basic issue emerges when there is a necessity of registering on such encrypted information where protection is built up. This paper represents homomorphic cryptosystems for preserving security, properties, and categories of homomorphic encryption. In addition to this, privacy-preserving applications of homomorphic cryptosystems in the field of cloud computing, private information retrieval, and data aggregation in wireless sensor network are also presented.

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Creative Commons Attribution 4.0 and The Open Definition

 Keywords

Cryptography

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Creative Commons Attribution 4.0 and The Open Definition

 Abstract

The objective of this study is to identify employee and employer relationship in the organization. The purpose of this research is to investigate the factors responsible for negative relationship between employer-employee. This is the primary research and data collected through structured questionnaire from the respondent who are employees of the organization. The main theoretical framework of this study focus on finding the factor that responsible for negative relationship between employer and employee.

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Creative Commons Attribution 4.0 and The Open Definition

 Keywords

Employee and employer relationship

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Creative Commons Attribution 4.0 and The Open Definition

 Abstract

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Creative Commons Attribution 4.0 and The Open Definition

 Keywords

Culture, Cultural Dimensions, Power Distance, Individualism, Collectivism.

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Creative Commons Attribution 4.0 and The Open Definition

 Abstract

Licence: creative commons attribution 4.0

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Creative Commons Attribution 4.0 and The Open Definition

 Keywords

Colonialism, British Rule, French rule, Missionaries, South India, women education, social reforms, Schools, Colleges.

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Creative Commons Attribution 4.0 and The Open Definition

 Abstract

The subject of our research is the problems of online classes of undergraduate level students in the COVID-19 situation in South 24 Parganas district. The three objectives we have studied are - to find out online class related problems of the Undergraduate level students in the COVID-19 situation, to find out how much the Undergraduate level students are aware of their online education in the COVID-19 situation, to know how the environment of the Undergraduate level student is conducive to their online education. The results we obtained through the pre-structured interview, participant observation and field survey techniques are -Lack of suitable environment for online classes, Internet problems, Problems with students' devices, Lack of well-trained teachers to teach online classes, Deterioration of positive teacher-student relationship, Problems of teacher-student interaction, Psychological problems of students towards online classes, Students' time management problems for online classes, Various problems related to students' education during online classes, Lack of board work and materials in online classes, Lack of acceptance of students towards online classes etc. The study has been conducted on the student of Fakir Chand college, Budge Budge College, Mograhat College, Vidyanagar college, Vivekananda college, Gour Mahan Sachin Mandal Mahavidyalay of south 24 Parganas district. The qualitative research method has been used for the study. This study reveals that at the undergraduate level, there are both positive and negative aspects of studying an online class, but by correcting the negative aspects or problems and making it better in the online class setup, students will be interested in learning and learning will progress very well in this COVID-19 situation.

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Creative Commons Attribution 4.0 and The Open Definition

 Keywords

Online classes, Internet, COVID-19 situation, Undergraduate level.

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Creative Commons Attribution 4.0 and The Open Definition

 Abstract

Licence: creative commons attribution 4.0

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Creative Commons Attribution 4.0 and The Open Definition

 Keywords

Appointment booking system, NLP, Speech-to-text,Deep Learning Model:Convolutional Neural Network, Recurrent Neural Network,Data Analytics

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Creative Commons Attribution 4.0 and The Open Definition