Volume 9 | Issue 4 |

 Abstract

Incidence and aetiology Ulcerative colitis is a long-term (chronic) condition and belongs to a category of disease known as Inflammatory Bowel Disease. . In Ulcerative colitis, the inner lining of child's large intestine (colon or bowel) and rectum gets inflamed. . Some patients also describe tenesmus. The onset is typically insidious. This inflammation often starts in the rectum and lower (sigmoid) intestine. Then it spreads to the whole colon. This causes diarrhoea or frequent emptying of the colon. As cells on the surface of the lining of the colon die and fall off, open sores (ulcers) form. This causes pus, mucus, and bleeding. In severe cases, purulent rectal discharge causes lower abdominal pain and severe dehydration, especially in the elderly population.

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KEY WORDS: Tenesmus, insidious, purulent rectal discharge, proctocolectomy.

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A tilting car is a special type of automobile that has the ability to change the angle between the road and the bottom of the passenger cabin in such way that there are reduced horizontal forces while driving through a curve.it may be 3 or 4 wheeler. These narrow track cars have an increased rolling tendency. The use of tilting mechanism in automobile would decrease the rate of accidents due to slippage. It will give better dynamic stability as well as directional stability to the vehicle, better road grip, and better comfort to the passengers, and the most important load carrying capacity of vehicle increases. In our project work we have tried to develop a tilting mechanism for the vehicle. This feature enables the vehicle to tilt in to the curve while negotiating it. The method we have used is a simple mechanical tilting system by using the shock absorbers. This tilting mechanism if successful would dramatically increase the maximum speed in curves. This would also provide the advantages of increased passenger comfort and handling. In order to develop a tilting mechanism for a narrow track car to give it the flexibility of a motor cycle. This can be operated on reduced lanes thereby increasing the effective capacity of highways.

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TILTING MECHANISM FOR A NARROW TILTING CAR TO INCREASE THE MAXIMUM SPEED IN CURVES

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With the number of Artificial Intelligence increasing and gaining popularity due to the emerging era of innovation and technological advancement, it spurs the discussion of what are the impacts of AI in the future of jobs. This study aims to objectively review published scholarly articles and assess the literature on the use of AI and its impact on the future of jobs. We hypothesized whether AI usage will displace the future of jobs. The Google scholar database was used to explore relevant literature sources. AI utilization that will augment and create more jobs than replacing them would be more useful in the future. Further research focusing on AI prediction outcomes on the future of jobs need to be developed to provide a clear approach and direction for the future.

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Artificial Intelligence, Future of jobs, automation

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This paper concerns with the problem of obtaining non-zero distinct integer solutions to the positive pell equation represented by the binary quadratic equation . A few interesting relations among the solutions are presented. Further, by considering suitable linear combinations among the solutions of the considered hyperbola, the other choices of hyperbolas, parabolas, order Ramanujan numbers, sequence of diophantine 3-tuples with suitable property are presented.

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Positive pell equation, binary quadratic, hyperbola , parabola,2^nd order Ramanujan numbers, sequence of diophantine 3-tuples. ,

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Emotional intelligence; Self-Awareness; Self-Regulation; Self-Motivation; Social skills; Social Awareness

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Christianity, Religion, The Movement

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A new, simple and precise RP-HPLC method was developed in this study for the quantitative analysis of lenalidomide (LLM) in pharmaceutical formulations using an analytical quality by design approach. Inertsil C8 mobile phase analytical columns containing a phosphate buffer were used for this purpose in the estimation of LLM and its degradation products present in the mixture of buffer, acetonitrile and methanol in the ratio 80:8:12 (v v/v). The 1.0 ml / minute flow rate is maintained and all degradation tests are conducted using the UV/VIS detector at 254 nm. Method Validation is carried out in compliance with the guidelines and criteria of the International Council for Harmonization (ICH); precision, accuracy, specificity, stability, robustness, linearity, quantization limit 0.25 ?gml-1 (LOQ) and detection limit 0.75?gml-1 (LOD) were successfully evaluated. The current RP-HPLC method indicates that the peaks' purity angle is less than their threshold angle, suggesting that it is ideal for stability studies. For the effective separation of LLM and its impurities in the pharmaceutical dosage formulations, the established method may therefore be used.

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RP-HPLC; Lenalidomide, Forced Degradation, ICH guidelines, Method validation.

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Organic farming, Eco-friendly, Fertilizers, Environment, Certification

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ABSTRACT Magnesium alloys are potential materials for automobile and aerospace industries due to its light weight, high strength-to-weight ratio, good cast ability, low elastic modulus, good machine ability and wear resistance. Among various Mg alloys, Mg-Si alloy have great potential for high temperature and wear resistance applications because of its hard Mg2Si phase. Howeverthe mechanical properties of the hypereutectic Mg-Si alloys are not satisfactory because of coarse brittle dendritic Mg2Si intermetallic and coarse lamellar eutectic Mg2Si phases. In order to increase its mechanical properties various researches are undergoing. Among that addition of Lanthanum (La) is the one of the optimum way to modify the Mg2Si phase. In the present study deal with the addition of La in Mg-6Si is to be investigated. Different proportions of Lanthanum (La) 0, 0.3, 0.6 and 0.9wt % effect is proposed to investigate. In order to understand the microstructure of modified/unmodified Mg-6Si alloy with different La addition will be studied using optical microscope and SEM analysis. The formation of La containing precipitate and its modifying mechanisms and morphology changes in Mg-6Si alloys is also will be investigated through XRD, SEM and EDX analysis. The mechanical properties of improved microstructure of Mg-6Si alloy due to the La addition is analysed by subjecting to its tensile and hardness tests.

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LANTHANUM ON Mg2Si IN HYPEREUTECTIC Mg-Si ALLOY

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