Volume 10 | Issue 4 |

 Abstract

Background. Alpha-tocopherol (?-T) is known to be the main bioactive form of vitamin E founded in plasma and tissues. A prior plasma dosage of both vitamin E and vitamin C is required before and during chemotherapy and radiotherapy, in order not to potentiate (when taking VE) a potential imbalance of the pro-oxidant/anti-oxidant balance at the origin of the appearance of metastasis and recurrence of cancer. The aim of this study was to analyse the variations in plasma alpha tocopherol and vitamin C levels in subjects diagnosed with breast or prostate cancer before any treatment. Methods. 30 samples were taken, 15 of which were subjects diagnosed with breast or prostate cancer and 15 healthy subjects as controls. Plasma assay was performed by high performance liquid chromatography. Results. Vitamin E varies in inverse proportion to the amount of vitamin C. An increase in one leads to a decrease in the other. Conclusion. The analyses showed that the plasma level of alpha tocopherol varies inversely with that of vitamin C. Hence the interest to take into account the vitamin status of these two micronutrients beforehand and to combine them during a supplementation. In order to avoid possible negative effects of this vitamin therapy.

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 Keywords

vitamin status, alpha tocopherol, vitamin C, breast and prostate cancer.

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Creative Commons Attribution 4.0 and The Open Definition

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Abstract Covid-19 has brought a renewed emphasis on health and sanitation, as well as, in unexpected ways, the need for productive employment opportunities in rural India. MGNREGA, the rural employment guarantee programme, has a mixed record of success in terms of providing adequate employment to those in need, the quality of asset creation, and the adequacy of wages offered. This paper makes the case for reorienting a small portion of MGNREGA spending to create micro-entrepreneurs from the reverse migrating masons, electricians, plumbers, and others in rural areas who directly contribute to augmenting health and sanitation infrastructure in the likely new normal. This will provide relief to those whose livelihoods have been severely impacted and, in the long run, will reduce reliance on government funds. We propose approving a new work type for sanitization works under MGNREGA without any complex asset creation and enlisting the private sector for project management skills to qAbstract Covid-19 has brought a renewed emphasis on health and sanitation, as well as, in unexpected ways, the need for productive employment opportunities in rural India. MGNREGA, the rural employment guarantee programme, has a mixed record of success in terms of providing adequate employment to those in need, the quality of asset creation, and the adequacy of wages offered. This paper makes the case for reorienting a small portion of MGNREGA spending to create micro-entrepreneurs from the reverse migrating masons, electricians, plumbers, and others in rural areas who directly contribute to augmenting health and sanitation infrastructure in the likely new normal. This will provide relief to those whose livelihoods have been severely impacted and, in the long run, will reduce reliance on government funds. We propose approving a new work type for sanitization works under MGNREGA without any complex asset creation and enlisting the private sector for project management skills to quickly skill up returning migrants and match work with workers on an ongoing basis. uickly skill up returning migrants and match work with workers on an ongoing basis.

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 Keywords

Covid, Sanitization, MGNREGA, Employment, Migration, Livelihoods

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A good financial accounting system is the most important requirement to operate a business effectively. When a new accounting standard adopt by a country for its own domestic companies for reporting their financial statement, it may be impact on the quantitative as well as qualitative attributes of financial statements. Every country stipulates a method for companies to report financial data based on rules called accounting standards. India has so far followed Indian Generally Acceptable Accounting Principle (IGAAP). But, on 16th February 2015, the Ministry of Corporate Affairs notified a set of rules called Companies ( Indian Accounting Standards) Rules 2015 w.e.f. 1st April 2015 introducing the Ind AS as a step towards convergence with IFRS for removal of difficulties and for ease of adoptability. This paper deals to know the impact of IND AS on various sectors.

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Keywords :- Accounting Standard, IGAAP, Ind AS, IFRS.

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Creative Commons Attribution 4.0 and The Open Definition

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Insomnia in depressive disorders, Single arm clinical trial, Interventional study, Homoeopathy

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Creative Commons Attribution 4.0 and The Open Definition

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Multilevel inverter is usually utilized in high voltage and high-power applications because of their lower filtering requirement smaller dv/dt changes medium voltage. But, as the output voltage level increase, the number of using the semiconductor device is increased. The demerit of conventional MLIs is that it requires a greater number of components which in turn increase the complexity of gate pulse generation. Therefore, the cost of MLI will increase. Conventional MLI topologies are classified into DCMLI (Diode Clamped Multilevel Inverter), Flying Capacitor, Cascaded h-bridge MLI (CHBMLI). In this paper we have used hybrid cascaded h-bridge MLI. It has more advantages over other topologies. It is proposed with a minimum number of switching devices like diodes, dc source etc. cost and space required is considerably reduced with increase in no of steps in output voltage. This paper includes the design and simulation of hybrid Cascaded h-bridge multi-level inverter using POD SPWM technique with R and RL load as shown in the paper

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 Keywords

Hybrid Cascaded H-Bridge Multilevel Inverter (Hybrid CHBMLI), Multilevel Inverter (MLI), Pulse Width Modulation (PWM ), Harmonics, Total Harmonic Distortion (THD), Phase Opposition Disposition (POD-SPWM), FFT(Fast Fourier Transform ), MATLAB.

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A sustainable building is designed to reduce its energy footprint and carbon emission. The thermal performance, solar access and ventilation of a building not only depend upon the ecological microclimate of the building but also on the behaviour of immediate site surrounding conditions. There are different parameters of sustainable performance which are affected by the boundary condition differently. This study tries to establish the need to study the immediate site surrounding in detail before starting the designing process and not just rely on climatic/microclimatic data of the site. Since the site surrounding conditions cannot be controlled, the building should be designed keeping in mind possible variations around the site and their ultimate effect on building performance. In this study, the performance parameters of the building will be evaluated concerning the boundary condition with the help of a literature study and CFD simulation of the case study. This study also reviews the existing methods and techniques to predict thermal behaviour, solar access and wind movement on a site neighbourhood-scale which will be helpful for calculating the performance parameters of the building.

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Boundary conditions, Solar Access, Ventilation, Thermal Performance

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Creative Commons Attribution 4.0 and The Open Definition

 Abstract

ABSTRACT The importance of transportation for the prosperity of any country cannot be overem-phasized.Transportation needs commensurate with infrastructural development demand shortest routes to cover distances. Bridge structures are the only solutions for such problems.Bridges are essential and vital elements of any road network. Now a days various Bridge construction works are going on all around the world as well as in our state.The vast majority of these bridges are of small or medium spans, where the slab or the beam and slab type of superstructure are the most suitable and preferred solution. It is observed that, In this slab type of bridges mostly 3 no.of Elastomeric bearings are provided to transfer the load from superstructure to sub structure. This only 3 no.of bearings transferring the whole load to substructure and foundation attracted my attention. So I decided to work on the Elastomeric bearings, the no .of bearings provided and its effects on the other structure of the project. Bearings are structural equipment or devices installed between bridge substructure and superstructure to transfer the applied load including earthquake loads; wind loads; traffic loads; and superstructure self-weight. Elastomeric bearings consists of elastomer manufactured from synthetic or natural rubber and can take both translation and rotation movements through elastomer deformation. The ability of elastomer to carry large vertical loads is because of reinforcement. In this project we consider Solid slab type of bridge superstructure of 10m to 15 m span length with open foundation. For each span length of superstructures we designed particular Elastomeric Bearings. For analysis firstly we provide 3 number of bearings and observed its effect on substructure and foundation by designing the substructure. After that we increased the number of bearings and provided 4 number of bearings .Observed the effect on substructure and foundation and found that the pier cap effects the most. We compared both the observations and concluded the result.

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Elastomeric Bearings.

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 Abstract

We report the observation of a 46-year-old man admitted to the emergency room for a sudden bilateral decrease in visual acuity limited to light perception with an ophthalmological examination and in particular of the normal fundus. Visual evoked potentials showed a lengthening of latencies, consistent with bilateral retrobulbar optic neuritis. Magnetic resonance imaging (MRI) revealed spinal cord and periventricular signal abnormalities in favor of Devic's neuromyelitis optica. The patient received a bolus of methylprednisolone for 5 days, followed by immunosuppressive treatment: antiCD20. The evolution was favorable with correction of visual acuity in both eyes

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Bilateral, retrobulbar, optic neuropathy, Devic Neuromyelitis optica

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A subframe is a part of a car's structure, which uses a different frame, which varies within a larger body frame or body body to carry certain parts, such as an engine, steering train and / or suspension. The subframe is bolted and even welded to form a single assembly, attached to a car frame or cabinet structure. The main objectives of using the subframe, are to distribute the upper chassis loads over a wide area of the thin metal sheet of the body shell, and to distinguish vibrations and sharpness throughout the body. The weighted subframe design has many split benefits. As, it carries the engine load, suspension and steering parts of the car, it should be designed to be lightweight, but without interfering with power.

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 Keywords

SUBFRAME, STEERING ,SUSPENSION,

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Creative Commons Attribution 4.0 and The Open Definition

 Abstract

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Creative Commons Attribution 4.0 and The Open Definition

 Keywords

Integrated Urban Water Management, Urban Water Management, Urban areas, Water Sector, Traditional Water Practices, Urbanization

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Creative Commons Attribution 4.0 and The Open Definition