Volume 12 | Issue 4 |

 Abstract

The importance of Computer Aided Drug Discovery (CADD) has been consistently increasing over the past 20 years. Artificial Intelligence (AI) is one of the CADD methods, machine learning (ML) is one of its subtopics. In the past five years , many Artificial Intelligence in Drug Discovery (AIDD) approaches were employed towards drug discovery . This article includes discussion on the scope and limitations of AIDD . Artificial intelligence (AI) has been transforming the practice of drug discovery in the past decade. Various AI techniques have been used in many drug discovery applications, such as virtual screening and drug design. In this survey, we first give an overview on drug discovery and discuss related applications, which can be reduced to two major tasks, i.e., molecular property prediction and molecule generation. We then present common data resources, molecule representations and benchmark platforms. As a major part of the survey, AI techniques are dissected into model architectures and learning paradigms. To reflect the technical development of AI in drug discovery over the years, the surveyed works are organized chronologically. We expect that this survey provides a comprehensive review on AI in drug discovery. We also provide a G it Hub repository with a collection of papers (and codes, if applicable) as a learning resource, which is regularly updated.

Licence: creative commons attribution 4.0

  License

Creative Commons Attribution 4.0 and The Open Definition

 Keywords

Artificial intelligence, Computer-assisted drug discovery, Drug repositioning, Machine learning, DSP- 1181

  License

Creative Commons Attribution 4.0 and The Open Definition

 Abstract

????????? ????? ??????? ????? ?? ?????? ???????? ?? ?????? ??? ???? ???????? ??? ?????????? ???????? ?????? ?? ??? ?????????? ??? ???????? ??????? ????? ?? ??????? ???? ??????? ?? ??????? ??????? ??? ??????? ?? ?????? ?? ??? ????? ??? ?????????? ????? ?? ?????? ??? ???????? ????? ??????? ??????? ????? ?? ????? ?????????? ?? ??????? ?? ???? ?? ?? ??????? ?????? ?? ?????? ??? ??? ????? ??? ?? ???? ??? ?????? ?? ????? ????? ?? ??????? ??? ?? ?????? ???????? ?? ?? ??? ??? ???? ???? ????????? ???? ?????? ???? ???????? ??????? ????? ?? ?????? ??????? ?? ???? ???? ??? ???????? ???? ?? ??????? ????? ??????? ????? ?? ?????? ?? ????????? ??? ???? ????????? ???? ?? ???? ???? ?? ?? ???? ?????? ?? ??????? ??????????, ????? ??????? ?? ????????? ?? ?????????? ????

Licence: creative commons attribution 4.0

  License

Creative Commons Attribution 4.0 and The Open Definition

 Keywords

??????? ?????, ????????? ?????, ????, ??????, ??????, ?????????, ????????, ??????????, ?????? ?????

  License

Creative Commons Attribution 4.0 and The Open Definition

 Abstract

The increased proliferation of online apps and services has raised serious concerns about the possibility of cyberattacks. SQL injection is a common attack type that takes advantage of holes in online applications to access databases without authorization. Maintaining the integrity and security of online systems depends on identifying and thwarting SQL injection attacks. In this study, we use the Sequential Minimal Optimization (SMO) algorithm to present a unique method for identifying SQL injection attacks in network traffic data. This study proposes a unique strategy that leverages machine learning to solve the critical requirement for efficient and effective detection procedures. This study specifically focuses on using the (SMO) technique to identify and mitigate SQL injection threats using network traffic data. The sequence of contacts between hosts, or network flow data, provides a wealth of information for identifying unusual patterns suggestive of attack activity.

Licence: creative commons attribution 4.0

  License

Creative Commons Attribution 4.0 and The Open Definition

 Keywords

: Network, SQL injection, Attack, Sequential minimal optimization algorithm, Defense Mechanism.

  License

Creative Commons Attribution 4.0 and The Open Definition

 Abstract

Postpartum psychiatric disorders are classified as puerperal blues, postpartum depression and postpartum psychosis. These are categorized by mood changes, irritability, weepiness, anxiety, confusion, insomnia, loss of appetite, delusions and suicidal tendencies. The conventional mode of treatment includes psychotherapy and psychotropic drugs which generally poses a risk to infant safety and long-term effects. Homoeopathy as an alternative mode treatment is the most gentle and harmless approach to manage postpartum psychiatric disorders.

Licence: creative commons attribution 4.0

  License

Creative Commons Attribution 4.0 and The Open Definition

 Keywords

Homoeopathy, Maternal Mental Health, Postpartum Psychiatric disorders

  License

Creative Commons Attribution 4.0 and The Open Definition

 Abstract

Producing money without the government's sanction is known as fake currency and it is a serious crime. An RBI research states that the number of counterfeit notes of the new Rs 500 series increased by 37% in 2019-20, while the number of Rs 2000 notes in circulation decreased. Not only banks but some other commercial institutions and establishments also now have resources and equipment to verify the legitimacy of the new notes . However, since the common people do not have means to access to these systems, there is a need for software that can be utilized by the general public to identify counterfeit money. The suggested solution makes use of image processing to identify if the money is authentic or fake. The creation of the system is primarily done using the python programming language.

Licence: creative commons attribution 4.0

  License

Creative Commons Attribution 4.0 and The Open Definition

 Keywords

counterfeit currency , segmentation , edge detection, gray scale, security thread.

  License

Creative Commons Attribution 4.0 and The Open Definition

 Abstract

The advent of technology in the realm of education system opens many opportunities for all. Advancement in technology give rise to the diffusion of knowledge in the era of 21st century which expedite the accessibility for users end. To contextualize and localize the resources in the field of vast arena of knowledge, Open Educational Resources plays a significant role to make the learning process easier and reachable to all.The study examined perception of Research Scholar about OER in Relation to Subject Studies and Gender was conducted on 45 M.phil and 45 Ph.D scholars from different streams such as Arts, Science and Commerce scholars of Ravenshaw University. Survey design was used to collect data from the participants by employing perception scale. Inferential statistics like Anova, t-test were used to analyze data. The main findings of the study revealed that the mean perception of M.Phil scholars about OER (140.31) does not differ significantly from their counter part of Ph.D scholars (140.08). It was found that both M.Phil & Ph.D scholar have the same perception about OER. There was no significant difference found between male scholars (140.05)and female scholars (140.29) about OER. So that it was found that both the male and female scholar having same idea and knowledge about OER.The mean perception about OER of Science research scholars (149.50),Arts research scholars (139.60) and Commerce research scholar (131.50) differ significantly. It was revealed that Science research scholars are more positively oriented towards the perception of OER than the Arts and Commerce research scholars.

Licence: creative commons attribution 4.0

  License

Creative Commons Attribution 4.0 and The Open Definition

 Keywords

Perception, Research Scholar, Open Educational Resources

  License

Creative Commons Attribution 4.0 and The Open Definition

 Abstract

Additive Manufacturing (AM) technologies, especially Fused Deposition Modeling (FDM), have witnessed widespread adoption in various industries due to their flexibility and cost-effectiveness. This abstract presents the design and fabrication process of a customized FDM-based 3D printer tailored for prototyping applications in the field of mechanical engineering. Key components of the printer, such as the extrusion system, are engineered to accommodate a wide range of thermoplastic filaments. A high-precision extruder with variable nozzle sizes facilitates the printing of intricate details. The motion system utilizes precise stepper motors, lead screws, and linear guides to ensure accurate and repeatable layer deposition.

Licence: creative commons attribution 4.0

  License

Creative Commons Attribution 4.0 and The Open Definition

 Keywords

3D printing, FDM, rapid prototyping, rapid tooling.

  License

Creative Commons Attribution 4.0 and The Open Definition

 Abstract

This study delves into the customer satisfaction levels concerning LG televisions at Rayalaseema Agencies, focusing on key objectives such as identifying influencing factors, understanding customer opinions, addressing problems faced by customers, and evaluating the overall satisfaction levels. Through a comprehensive analysis combining surveys and customer feedback, the research aims to uncover the factors that significantly influence customer satisfaction with LG televisions. It examines various aspects such as pricing, product features, customer service, and brand reputation to understand their impact on customer opinions and purchasing decisions. Additionally, the study investigates the problems faced by customers during the purchase, installation, and usage of LG televisions, seeking to identify common pain points and areas for improvement. By addressing these ssues, Rayalaseema Agencies can enhance the overall customer experience and satisfaction levels. Furthermore, the research assesses the level of satisfaction among customers who have purchased LG televisions from Rayalaseema Agencies, providing insights into areas of strength and areas needing attention. Understanding customer satisfaction levels s crucial for Rayalaseema Agencies to tailor their strategies and services to meet customer expectations effectively.

Licence: creative commons attribution 4.0

  License

Creative Commons Attribution 4.0 and The Open Definition

 Keywords

Customer satisfaction, LG televisions, Rayalaseema Agency, influencing factors, customer opinions and overall satisfaction.

  License

Creative Commons Attribution 4.0 and The Open Definition

 Abstract

We have seen such a rise in global warming and pollution over the years. There is a change in the vegetation and food chain, the wetlands are vanishing. We humans have destroyed the environment that we need to survive. This doctrine shows consistency with the present environmental issues. The public trust doctrine enforces a legal right for the citizens under Article 21 and gives a positive duty to the state to preserve and safeguard the environment. The paper concludes that the public trust doctrine is a very effective way to solve all the environmental issues and conflicts in a proper legal framework, as India does not have separate environmental protection laws. By promoting the public trust doctrine we are promoting the protection of the earth and its resources.

Licence: creative commons attribution 4.0

  License

Creative Commons Attribution 4.0 and The Open Definition

 Keywords

Public trust doctrine

  License

Creative Commons Attribution 4.0 and The Open Definition

 Abstract

To study the NMR spectroscopy. The NMR spectroscopy is nuclear magnetic resonance spectroscopy. Which is widely used in these year because of it gives the accurate measurements and graphical notation. Nuclear magnetic resonance is use to study the physical, chemical,and biological properties of matter (4)the basic components in the nmr spectroscopy is atom and it's proton number. the proton give the magnetic movement to the compound hence it is summarized that it is useful in structure identification. In the pharmaceutical analysis the NMR spectroscopy used in identification and frequency testing of carbamazepine. The carbamazepine frequency and testing is done with h1 NMR spectrum

Licence: creative commons attribution 4.0

  License

Creative Commons Attribution 4.0 and The Open Definition

 Keywords

NMR,radio frequency, magnetic filed,nuclear shielding, spin

  License

Creative Commons Attribution 4.0 and The Open Definition