Volume 11 | Issue 3 |

 Abstract

The use of mucoadhesive drug delivery systems is a promising innovation in the field of pharmaceuticals. Mucoadhesive drug delivery systems are particularly relevant for getting local and systemic drugs distribution in the Gastro Intestinal Tract (GIT) for a prolonged period of time at a predetermined rate. This is in contrast to oral controlled release drug delivery systems, which are often subject to extensive presystemic metabolism and degradation in the acidic environment of the stomach, resulting in insufficient absorption of the drugs. One of the advantages of mucoadhesive drug delivery systems is that they allow for direct passage of medication into the systemic circulation through the buccal mucosa, which is the lining of the mouth. This results in easy administration without pain, brief enzymatic activity, less hepatic metabolism, and higher bioavailability of the drug. Additionally, mucoadhesive drug delivery systems do not require extensive patient compliance or supervision, as is often the case with parental drug delivery systems.The mechanism of mucoadhesion involves the interaction between the mucoadhesive polymer and the mucus layer of the mucosal surface. Mucoadhesive polymers are designed to adhere to the mucosal surface and remain in place for an extended period of time, allowing for a sustained release of the drug. In-vitro and in-vivo mucoadhesion testing techniques are used to evaluate the efficacy of the mucoadhesive drug delivery system.In summary, mucoadhesive drug delivery systems offer several advantages over traditional oral controlled release and parental drug delivery systems, including higher bioavailability of the drug, ease of administration, and sustained release. Further research is needed to optimize the design of mucoadhesive drug delivery systems and to fully understand their potential in the field of pharmaceuticals.

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 Keywords

Buccal drug delivery system, Mucoadhesive drug delivery system, Mucoadhesion, mucoadhesive polymers, Permeation enhancers, Bioadhesive polymers

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Nonlinear optics (NLO) single crystals are materials that exhibit strong nonlinear optical properties and are critical for the development of various optical applications. The growth and characterization of NLO single crystals play a significant role in determining their optical and physical properties. The growth process involves melting the starting material and cooling it to form a single crystal. The resulting crystal's quality is dependent on various factors such as the purity of the starting material, the growth rate, and the control of the crystal's morphology. Characterization techniques commonly used include X-ray diffraction, Fourier transform infrared spectroscopy, UV-Visible spectroscopy, and second harmonic generation. These techniques provide information on the crystal's structure, orientation, molecular structure, optical properties, and nonlinear response. Overall, the growth and characterization of NLO single crystals are critical for the development of various applications that rely on the strong nonlinear optical properties of these materials.

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Characterization, growth, Nonlinear optics , single crystals, UV-Visible spectroscopy, X-ray diffraction,

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The discussion is on the historical background of mob lynching in India and how it has recently increased as a result of mob violence and the dissemination of false information on social media platforms. We need better policies and governing statutes and regulations to mitigate and prevent the "horrendous act of mobocracy�. Mob lynching is a very serious threat to established social order and belief in the rule of law. The research paper also dealt with scenarios within other countries relating to such crimes. The responses of the judiciary and parliament of India have also been discussed. Today, lynching is being carried out in an organised manner, like a parallel judicial system. In Indian society, "vigilantism� was prevailing, but this type of apparent authority was never granted to the offenders in the real sense. The main objective of the research paper is to understand the historical background, study the reasons behind the increasing incidents of mob lynching, and also study the constitutional and human rights perspective of lynching. This research work may contribute in measure to a better understanding of this most serious and difficult problem, which is the hope with which it is placed in the hands of the reader. Briefly, this research paper also delves into the social, economic, and political effects of lynching on the victims and their immediate relatives. Overall, this paper highlights the urgent need to address the issue of mob lynching in India from a human rights perspective, with a focus on the constitutional framework and international human rights standards.

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 Keywords

Mob Lynching, Human Rights, Constitution of India, Law Enforcement, Due process Vigilantism, Hate Crimes, Judicial Activism, Free speech, Democracy

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Spirituality means the quest to know one's true Self, to find out the real nature of consciousness. This search is the foundation of all great spiritual teachings, the goal of all great mystics. Paulo Coelho's novels basically deal with the spiritual journey of his protagonists. This journey at some points is hindered by some factors and leads to the moral downfall of the protagonists. His novel 'The Winner Stands Alone' portrays the importance of morality or rather lack of morality in the pursuit of the materialistic dreams. The novel portrays a character that has already reached his material destination and ignores the spiritual aspect of life by perusing false ideals. The novel depicts a conflict between materialism prevalent in the modern world and the spiritual aspect of life that man neglects while perusing false ideals.

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spiritualism. materialism, superclass, humanity

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Kids are reflection of good luck and symbol of happiness. They are loved and protected, decorated by beautiful and comfortable clothes; each country in the world has a different way of how parents cover and wrap their babies and children. As their skin is soft, mothers gently try to keep their babies warm and comfortable with soft cloth as they can afford to get. Since the past, children have been considered as miniature adults and are expected to behave as adults. Their clothing has been designed in a similar fashion to adults. At present, a special emphasis is placed upon children and their needs, with the attitude that children should be given freedom of expression. Their clothes should be created according to their age group and an activity, as the growth and development of children is affected by the clothes they wear. Now-a-days there is awareness in children regarding their clothing and they actively participate in the selection of their clothes. They prefer well-fitted and comfortable garments

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children' wear, media and information utilization, clothing design preference

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John Locke is eminently known for his influential work and contribution on political philosophy. In fact, he is one of the most famous and influential political philosophers. His work on political philosophy is best expressed in his book Two Treatises on Government (1689). Various intriguing topics has been critically discussed and analysed in this book. I shall critically discuss Locke�s political philosophy and it�s influence. Locke�s most famous and influential ideas can be found in his Second Treatise where he puts forward so many ideas which is very much in owe till today. I shall try to highlight few important ideas of Locke which remains hugely influential to this modern day period. Locke�s influence is definitely worth rethinking and worth discussing. So many of his ideas can be found in politics of almost all Asian countries and also in the United States. Democracy which most countries now abides, owe its origin and ideas to Locke. The American constitution hugely owe to Locke. Thomas Jefferson, the founder of the American constitution has borrowed ideas from Locke which makes Locke a co-founder of the American constitution. The natural rights to life, liberty and property was also seen to borrowed from Locke. Jefferson laid a similar one where only property has been interchanged with happiness.

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John Locke, Political Philosophy,

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Technical analysis is made by investors & traders for decision making of investments in both developing and developed markets. The main tools of technical analysis are MACD (Moving Average Convergence Divergence) and RSI (Relative Strength Index) which are used to determine future trend of prices of stock. In country like India, being a developing market, technical analysis usage by investors is limited to the use of MACD and other nominal indicators. The research covers sample representing the equity which are continually traded on the NSE. This research is helpful to determine the applicability of MACD and RSI indicators for a Profitable investment decision making on Indian Financial Market. The main objective of the research is to identify the potential contribution of standard MACD and RSI indicators vis-�-vis optimized MACD and RSI indicators. The main hypotheses of the research is that the application of standard MACD and RSI indicators contribute to profitable investments than buy and hold strategy (Efficient Market Hypotheses). The tools of data analysis include Excel Mathematical calculations. Research results indicate that the buy and hold strategy results in profitable investments than standard MACD and RSI indicators. According to the obtained results it is concluded that Optimized MACD and RSI indicators are more profitable than buy and hold strategy. And hence Optimized MACD and RSI indicators defy Efficient Market Hypotheses.

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Ratio Indicator Moving Average Technical Ananlysis Signal of buy or sell

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Promotion is the act of providing the information about the product or service by the marketing manager n, manufacturers or else to the customers or buyers so that they can become aware about the product. It is kind of communication process. The study throws light on the concept of promotion, promotion schemes, why promotion schemes are important for the organization or company. The study also describes various types of promotion schemes which are used by many companies, The focus of the paper is to study the meaning of promotion schemes band its effectives.

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Promotion, Promotion Scheme, Promotion Mix, Awareness, Pull and Push Strategy.

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The role of chromium prepared microwave irradiation method

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Tungsten oxide, chromium doping, semiconducting oxide

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This research gives an encapsulation the distinguished craft in "the city of -Nawabs�. Chikankari is an especial innate part of Lucknow culture and craft cycle. From the dawn of civilization, people have valued culture. Every community engaged in some sort of artistic or crafty activity. In addition to technical advancement and creative solutions, the transition to a sustainable society calls for a robust cultural sector that encourages changes in consumption and production. The need for sustainability in the present day situation is rising. This is also in concur the Indian craft of conventional accessories forming utilize Chikankari waste fabric exquisite which socially focuses on creating life style accessories product and could be regal or experimental. Develop accessories items and reuse old preserve chikankari fabric. In this study its aims to establish the social impact of this craft with sustainable through optimization and waste reduction.

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Chikankari, Craft, Accessories, Sustainable, Waste, Social impact, Life style accessories product, Traditional, regal, Embroidery.

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