Volume 11 | Issue 3 |

 Abstract

Multiply and Accumulate operation is one of the fundamental methods in signal processing and other areas (MAC). A digital signal processor's (DSP's) multiplier is the device's single most important physical component. Power consumption, LUT use, and latency are the limited factors in Digital signal processors performance. The development of a low-power, low-latency multiplier is so essential. The study's focus is on finding the best design for a 16-bit MAC unit that employs a multiplier and a carry save adder with a bit depth of 8. We may make use of the booth multiplier as a benchmark. Verilog HDL is used throughout the whole of the design's implementation. Vivado 2018.2 was used for both the synthesis and the simulation. The proposed architecture provides a means of drastically cutting down on the waiting time. The energy consumption is reduced by almost 15% as a result.

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 Keywords

Vedic mathematics, carry-save adder, MAC unit, Verilog HDL, Look-up Table

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Dapagliflozin Propanediol Monohydrate, sitagliptin phosphate monohydrate, Stability indicating RP- HPLC Method, Validation.

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In order to provide long distance endurance and ensure the minimization of a cost function for electric vehicles, a new hybrid energy storage system for electric vehicle is designed in this paper. For the hybrid energy storage system, the paper proposes an optimal control algorithm designed using a Li-ion battery power dynamic limitation rule-based control based on the SOC of the super-capacitor. At the same time, the magnetic integration technology adding a second-order Bessel low-pass filter is introduced to DC-DC converters of electric vehicles. As a result, the size of battery is reduced, and the power quality of the hybrid energy storage system is optimized. Finally, the effectiveness of the proposed method is validated by simulation and experiment.

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BESS, Circuit breaker, switch off time period, ESS.

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Infidelity of women is a recurrent topic throughout fiction. Attitudes toward this infidelity always mark a woman with grave accusations. In human history to look for love or comfort elsewhere when it is lacking in your own home or to take a stand for yourself against the attitude of your partner is forbidden. Look what happened to Ophelia when she returned all the favors made by Hamlet in order to break off what they had, she was asked to leave for a 'nunnery.' She was called an immoral and cold-hearted beast. It gave rise to wild speculation among readers. This paper discusses R.K. Narayan's efforts to redefine the stand of women in society in the 1960s through his character Rosie in The Guide. It exhibits the helplessness or deprecated situation of women under the purview of a patriarchal society. Throughout his fiction, Narayan held Rosie in defence of her actions. He did not approve of the socially approved method of subduing women by denying them decision-making powers, dignity, pride and self-esteem.

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Infidelity, feminism, Indian women, marriage

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Oral Dispersible Tablets Are Patient Friendly Dosage Form That Rapidly Disintegrate Or Dispersed In Mouth Without The Need Of Water. Oral dispersible tablet of Hydrocortisone was develop in present study to get rapid onset of action to increase bioavailability and to increase patient compliance In The Present Investigation Ten ODT Formulations Of Hydrocortisone its is used Arthritis, Blood ,Hormone ,Immune System Disorders, Skin And Eye Conditions, Breathing Problems And Severe Allergies.Were Prepared different formulation by Using Different Superdisintegrants like Sodium Starch Glycolate , Crospovidone Cross Carmellose,Sodium Microcrystalline Cellulose , Aspartame, Magnesium Stearate , Talc , Aerosil Pineapple Flavour Mannitol By Direct Compression Method. The Effects Of Different Concentration On The Release Profile Of Hydrocortisone ODT Were Studied. Developed ODT Were Studied For Their Physicochemical Properties And In Vitro Drug Release Profile. The Studied Parameters Were Found To Be Satisfactory For All ODT Formulations Of Hydrocortisone Disintegration Time For All The Formulations Was Found To Be Less Than 30 Seconds. Disintegration Time For All ODT Decreased With Increase In Disintegrant Concentration. The aim of study is to develop and evaluate the oral dispersible tablets of Hydrocortisone To improve patient compliance,develop cost effective product. and enhanced the onset of action of Hydrocortisone also enhance the safety and efficacy of Hydrocortisone.

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Oral Dispersible Tablet , Hydrocortisone Fumrate

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The founder of psycho-analysis movement was Sigmund Freud (1856-1939). The present conceptual paper throws light on his views on different aspects of psychoanalysis. According to him, each behaviour of the individual is the resultant of the dynamic interaction among three forces: id, ego and super ego at the conscious, sub-conscious and unconscious level. He had always considered the influence of the sexual drive as absolutely crucial point in his theory. Freud also placed great importance on two instincts: 'Eros' and 'Thanatos' as the ultimate cause of all human actions. He developed his own techniques of free association and dream analysis to explore and fathom into the unconscious motives of the individual's personality. Freud organized his personality theory around five psycho-sexual stages of development which affect the individual's whole life. He opined that all behaviour is caused or motivated even forgetting is also motivated. This paper also focuses on critical evaluation of Freud's theory by Neo-Freudians who deviate from Freud but claim to be psychoanalysts. Though Freud's theory of psychoanalysis is vehemently criticized still his views continue to influence modern education.

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Psychoanalysis, instincts, free association technique, dream analysis.

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India followed a democratic secular system. India considered all religions are equal. Pakistan established a Muslim state and aimed to build up its political foundations on the basis of Islam. The following major issues and problems determined the nature of Indo-Pak relations; Transfer of Populations and Problem of Religious Minorities, Indus Water Treaty 1960 or Sharing of River Waters, Boundary Dispute, Evacuee Property, Issues of Integration of Indian Princely States, Bus Journey by Vajpayee, The Pattern of Pakistani Air Operations in Past Conflicts, Kashmir Operations, The Dispute of Rann of Kutch 1965, India-Pak War of 1965, India-Pakistan War of 1971, Indian Bombardment continue in Kargil Area (May 28, 1999), etc shows a comprehensive view on India-Pak relations.

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Kashmir Operations, Religious Minorities, Indo-Pak Relations, Integration, Sharing of River Water, etc.

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Bengaluru city is one of the major fastest growing metropolises, with an 8.50% economic growth, and has world-class housing, education, and research facilities in the country. Over 36% of the economy of the State of Karnataka and 98% of the State's software exports come from Bangalore, making it a significant contributor to the economy of all of India. In the past 20 years, the population is growing at faster pace and almost has doubled facing the challenges of traffic and transportation problems. The existing BMTC (Bengaluru Metropolitan Transport Corporation) is working hard to meet the demands of the increasingly growing commuter population for a quick, more efficient, and user-friendly method of public transportation but is still unable to accomplish, hence there is need for developing an efficient MRTS (Mass Rail transit System). Namma metro is one of the few MRTS projects undertaken in India and perhaps to became the first underground metro system in South India. The objective of the study is to understand the benefits that the metro projects provide are more important from the government's economic and social point of view compared to the financial benefits that accrue from implementing the project. This paper discusses about the Namma Metro improving the traffic and transportation problems in Bangalore city providing numerous benefits to the citizens and society, such as. savings in fuel consumption, vehicle operating costs, travel time, reduction in road accidents and air pollution etc. These economic benefits would overweigh the financial benefits and hence assessing the same would also be of more significance. It further attempts to investigate the Economic Analysis using Framework for Economic Appraisal based on MOHAU (Ministry of Housing & urban affairs) Appraisal Guidelines for metro rail projects to enumerate all benefits and the economic viability of the project of Namma Metro Phase- I.

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Public Transport, Namma Metro, Economic Analysis, Cost-benefit Analysis (CBA).

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Fitness, good health, appearance, and self-presentation are now considered to be personality traits. Nutritional supplements are appropriate in our contemporary cultural context and can be taken orally to improve fitness, good health, and aesthetics. 20% of your skin is only addressed by topical skincare solutions. According to Dr. Howard Murad, the remaining 80% of your health is influenced by what you eat, drink, and take in, including dietary supplements. For the purposes of beauty and good health, herbs from Ayurveda and Traditional Eastern Medicine (TCM) are becoming more and more well-liked because of that competitive effectiveness of nutricosmetics and reduced unwanted toxic effects. Chemicals from natural sources are continually being sought after by the cosmetics sector In order to promote endogenous antioxidant enzymes that may help to internally handle principle of oxidative stress and aid to attain a healthy skin look from the inside out. nutricosmetics offers nutritional antioxidant supplements. The aims of this review article to provide an overview of the nutricosmetic ingredients that improve health and fitness by acting on the skin, hair, and nails by act on the systemic level that's aim focus on beauty health and fitness.

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nutricosmetics, health, ingredients, Beauty, fitness.

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Dostarlimab (JEMPERLI), a PD-1 monoclonal antibody, is used to treat adult patients with advanced or recurrent endometrial cancer who have progressed while receiving treatment with a platinum-containing regimen or after receiving prior therapy. This application was swiftly approved based on the rate of tumour response and the length of the response, both of which were determined using an FDA-approved test. The continuation of approval for this indication is dependent on additional confirmatory trials proving and proving therapeutic benefit. The clinical trial NCT04165772 showed a rectal cancer remission rate of 100% in June 2022. This clinical trial demonstrated that it is possible to match a tumor's genetics with its treatment. Patients are still being enrolled in this research trial, A few decades ago, the incidence of colorectal cancer was low. Nonetheless, it has emerged as a common malignancy and now represents 10% of cancer-related deaths in western nations. The "surge" in colorectal cancer cases in developed nations is thought to be caused by an ageing population, poor modern eating practises, and an increase in risk factors like smoking, inactivity, and obesity. Laparoscopic surgery for primary disease, more aggressive resection of metastatic disease (such as liver and pulmonary metastases), radiotherapy for rectal cancer, and neoadjuvant and palliative chemotherapies are some of the new treatments for primary and metastatic colorectal cancer that have emerged, giving patients more options. On cure rates and long-term survival, these new therapy alternatives haven't made much of a difference.

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 Keywords

Dostarlimab, Jemperli, Monoclonal Antibody, Colorectal cancer.

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