Volume 12 | Issue 3 |

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Abstract: Aim: This study is aim to assess the Prevalence, Risk factors, Medication Adherence, Drug Utilization Studies in MYOCARDIAL INFRACTION. Objectives: The key objectives of the study include: ? To evaluate the Risk Factors in Coronary Artery Disease Patients. ? To access the Medication Adherence in Coronary Artery Disease Patients. ? To determine the Drug Utilization patterns of Cardio Vascular Drugs. Methodology: Our study is prospective, observational conducted in cardiology department of govt. general hospital attached to Kurnool medical college. The sample was collects based on inclusion and exclusion criteria in the patient data collection proforma. Conclusion: The prevalence of myocardial infraction is very high and, on the rise. Prevalence of Myocardial infraction is higher in men, whereas the mean age of women at the time of incidence is higher. The majority of risk of myocardial infraction can be explained by Alcohol use, Smoking, Hypertension and Diabetes mellitus. Medication adherence in our study was seen to be reducing over 3 months due to factors such as low monthly income and low educational status of the subjects. Our study showed that initiation of treatment in both the genders and various age groups. The difference in the use of drugs on hospital admission might be due to the varied clinical presentation. Our study leads us to the conclusion that the proportion of prescription medications with generic names needs to increase

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Index Terms - Mi - Myocardial Infractiom Sa - Sino Atrial Av - Atrio Ventricular Cad - Caronary Artery Disease Hf - Heart Failure Vdh - Valcular Heart Disease.

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Data Science tools such as MATLAB, Big ML are used to handling the uncertainty and noise in compressed cloud data storage at different accessing terminals in web applications. The Cloud computing significantly plays a role in the aspect of effective resource utilization and service consumption. Irrespective of the type of clouds (ex. Private, public, hybrid or inter-cloud), every service providers concentrates on the data residing in cloud servers. Each and every moment, the researchers and scholars are proposing multiplicity of security algorithms to secure cloud data during the transactions. Most of the cloud data secure algorithms are focusing on the way to secure to cloud data in a single direction by using cryptographic algorithms. In this research paper focuses on a new direction to combine the features of data compression with the cloud data in order handling the way of uncertainty as well as removing noise in compressed cloud data storage.

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Data Science Cloud, data, storage and compression.

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The use of certain drugs during the pregnancy might pose a risk to the developing foetus, raising concerns about the potential adverse effects on the foetal development and maternal health. This abstract will provide an overview of the intolerant drugs during pregnancy, focusing on their pharmacological activities, mechanism of crossing the placental barrier, and associated risks. Drugs that cross the placenta can impact foetal development by affecting the organs and systems, which leads to the congenital abnormalities and many other complications. The main factors that might influence the passage of the drug to the foetus might be the size, molecular weight, ionisation, or its binding strength. Some common examples of the ''Intolerant Drugs'' are: Thalidomide, ACE Inhibitors, Warfarin, Tetracyclines, Retinoids, and Ribavirin. All of these drugs have been evident to show some severe birth defects like limb abnormalities, kidney functioning issues, heart defects, or sometimes it can be fatal. It's important to note that the assessment of drug safety during pregnancy is complex, and varies under different circumstances. Healthcare workers play a crucial role in the evaluation of the risks and benefits of medication use in each case, considering factors such as the specific drug, the trimester of pregnancy, the health status of the pregnant individual, and alternative treatment options. Henceforth, this Abstract emphasises on the importance of medical guidance and reducing the risks associated with drug exposure during the pregnancy.

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Intolerant drugs, foetal development, placental barrier, abnormalities, drug exposure, drug safety, medical guidance.

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This research investigates the early detection of faults in bearings at the inner and outer race using condition monitoring techniques. Bearings play a critical role in various mechanical systems, and early fault detection is essential for preventing catastrophic failures and minimizing downtime. The study aims to evaluate the effectiveness of condition monitoring methods in identifying faults in both inner and outer races of bearings. A comprehensive literature review is conducted to provide context and identify gaps in existing research. The methodology involves selecting appropriate bearing types and fault scenarios, designing an experimental setup, and employing various conditions monitoring techniques for data acquisition and processing. Data analysis is performed to identify fault signatures and assess the accuracy of fault detection. Results indicate the efficacy of condition monitoring techniques in detecting faults at both inner and outer races, with insights into factors influencing early fault detection. The findings contribute to enhancing bearing maintenance practices and provide valuable guidance for future research in the field of condition monitoring.

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Bearings, Condition monitoring

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INTRODUCTION: Diffuse Axonal Injury(DAI) is a severe form of Traumatic Brain Injury(TBI) characterized by widespread damage to axons. While conventional treatments aim to manage acute symptoms, there is limited focus on addressing residual neurological deficits in the long term. In Ayurveda, TBI corresponds to Shiro-marma Abhigata and one among the Nidana of Vata Vyadhi. MATERIALS AND METHOD: This case study was conducted on a 28-year-old female patient who met with a road traffic accident resulting in DAI and severe head injury four years earlier. Since the neurological deficits persisted, the patient underwent a 27-day Ayurvedic treatment which included internal medications and Panchakarma procedures. RESULTS: The functional Independence Measurement(FIM) tool was used for the assessment. The patient improved her cognitive function, motor skills, and emotional well-being throughout the treatment. The FMI score recorded at the baseline and the end of the treatment showed a remarkable difference of 23 units thus improving the patient's QOL. DISCUSSION AND CONCLUSION: Therapeutic procedures such as Mrudhni taila, Madhutailika Basti, and internal medications effectively manage such disabilities. This study highlights the potential of Ayurvedic medicine as an effective and safe integrative approach for palliative management of the residual symptoms due to DAI such as tremors, memory loss, imbalance, and weakness. Thus, personalized and holistic methods of Ayurveda offer a promising avenue for improving the quality of life in individuals with neurological impairments.

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Shiroabhighata, Palliative care, Post Traumatic Care, Rehabilitation in Ayurveda, Case Report

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Twentieth century age witnessed disintegration in ethical, philosophical and religious values in the life of the West. The problems of alienation, fragmentation and anxiety infused the sense of lack of direction and disbelief in the existing values which were aggravated by the deadly World War. T. S. Eliot (1888-1965) as a creator of modern sensibility employs his intellectual bent of mind to give objective expression to the chaos and loss of identity in modern life. He is the watershed of modern literary movement especially in poetry. He employs fragmentation in his poetry to demonstrate the disintegration of the modern European society. He is not pessimistic in showing this, rather he puts across a road map to wriggle out of the painful psychological condition. The present paper traces the process that begins with psychological fragmentation of modern Europe which ends in hope of spiritual renewal and reintegration.

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Fragmentation, alienation, anxiety, disbelief, reintegration, modern sensibility

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Dysfunctional uterine bleeding it includes menorrhagia, metrorrhagia, polymenorrhea, fibroids,The research approach adopted for this study is quantitative approach. The research design adopted for the study was descriptive design . The sample consist of 100 women aged 30-45 years selected at maternity hospital , Tirupathi . The knowledge was assessed by using self structured questionnaire . Booklet was given to the study participants on the same day. The result shows that 50% had inadequate knowledge and 35% had moderate knowledge and 15% had adequate knowledge. The calculated Standard deviation 14.50 mean value(47.31).The result clearly showed that women had lack of knowledge regarding dysfunctional uterine bleeding.

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Assess ,knowledge, Dysfunctional uterine bleeding, women

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Excellent and broad bio-spectrum of amide derivatives has generated an attractive platform for synthetic chemists to introduce structural modification in its nucleus by conventional access to new approaches. A new sequences of various amide derivatives have been design and synthesized. The methodology is proficient and simple to perform, giving the desired amides with excellent yield. An innovative series of four derivatives of amide were synthesized by the condensation of different compound like acetanilide, aniline, sulphanilamide and urea with benzoyl chloride in presence of sodium hydroxide as a catalyst. The reactions steps and the purity of the products were crisscross by using Thin Layer Chromatography (TLC). The chemical structure of final compounds were characterized and inveterate by measuring their melting points, elemental analysis, IR and 1H-NMR. The in-vitro antibacterial activity is done by using disc diffusion methods. The compounds were confirmed at different concentration from 0.02-0.10mg/ml in order to plaid the percentage inhibition of compounds. From the result compounds A1 and A2 presented highly significant activity against gram positive bacteria in comparison to standard sulphanilamide. A preliminary study of antimicrobial activity was performed in which antibacterial activity was done in two strains of bacterial activity was done. The results showed that compounds A1 and A2 have significant antibacterial activity compared with standard drugs and the other tested compounds have moderate to good activity.

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amide, antibacterial activity, antimicrobial activity

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