Volume 12 | Issue 3 |

 Abstract

Oral administration is the most convenient and preferred means of any drug delivery to the systemic circulation.Controlled-release drug delivery systems (CRDDS) provide drug release at a predetermined, predictable and controlled rate required for therapeutic effect. To improve the solubility and bioavailability of poorly water soluble drugs, solid dispersions is the most frequently used. Amongst solid dispersions, lipid based carriers had a higher success rate in enhancing the bioavailability of Class II drugs (Furosemide), one such promising group of carrier is Phospholipid (soyalecithin). The aim of the present work was to prepare phospholipid solid dispersion of Furosemide (PLD) with soy lecithin in different ratios using solvent evaporation method. The prepared PLD4 was used to prepare core tablets (F1-F5) using polymers HPMC K4M & E15, which were further subjected to compressed coat (C1-C5) using sodium bicarbonate, PVP K 30 and HPMC E5. Post-compression parameters of Furosemide tablets were evaluated. Formulation F4 core tablet was optimized having drug release of 93.31% in 12 hrs, drug content was 99.50%, floating lag time 16sec with floating time 12 hrs. Among compressed coated floating tablets of Furosemide, C3 has shown 93.31% release with zero order release pattern.

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 Keywords

Solid dispersion, soyalecithin, floating lag time, higuchi equation, compressed coated

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 Abstract

pharmacotherapy benign prostatic hyperplasia includes various options with differing side effect profiles, including alpha blockers, 5-alpha reductase inhibitors, phosphodiesterase inhibitors, anticholinergics, and beta-3 agonists, each with unique efficacy and safety considerations.

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 Keywords

Benign prostatic hyperplasia , alpha blockers ,5 alpha reducters inhibitors,phosphodiesterase inhibitors,anticholinergics ,beta 3 agonists

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It is vital to conserve energy for evolution, growth, and survival as it is a component of day-to-day life as well as increase in demand. India as a nation developing country and require focusing on energy. Energy conservation with proper methodology like energy audit can be proper solution. The paper focuses on the importance of energy conservation by considering the loads of a forging plant having a contract demand of 450 kVA with HT1 connection considering the energy consumed by the present loads and recommending energy efficient technology.

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 Keywords

Energy, Forging

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Satisfaction and success in life is directly linked to the vocational success. The present study aims to compare the vocational Interest of Muslim adolescents and to study the effect of their family background factors on vocational Interest. For this purpose 100 Muslim Adolescent from Dist. (U.S.N.), Uttarakhand were selected through simple random sampling.Vocational Interest Record developed by Bansal V.P. and Srivastava D.N. was used. The collected data was analyze using t- test and ANOVA test. Result revealed that boys were found slightly more interested than the girls in agriculture area. Whereas girls were shown more interest in household jobs than boys. Muslim boys and girls in reaming areas namely : artistic, executive commercial, literary, scientific and social field found insignificant result at 0.05 level of significance at df 98. No significance difference found in the vocational interest of rural and urban Muslim adolescents.

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Key words: Vocational Interest, Muslim Adolescent

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Abstract: Background of the study: Through these years chemotherapy nurses have mastered clinical expertise in areas which contribute to patient care. Research Methodology: An evaluatory research approach was used to find out the effectiveness of VAT on safe handling of cancer chemotherapeutic drugs for GNM nursing students is pre experimental one group pre-test post-test design. Dependent variables: Knowledge level of nursing officers cancer chemotherapeutic drugs. Independent variables: Video teaching programme. Data collection: Demographic variables and structured knowledge questionnaire was developed. Results: Descriptive and inferential statistics. The effectiveness of VAT was identified using frequency and percentage. Paired 't' test was used to find out the significant difference between the pre-test and post-test knowledge scores and the mean post-test knowledge scores (32.was higher than the mean pre-test knowledge scores (16. 2). The computed 't' value is18.87 .is higher than the tabled value t 49 at p<0.05 .level of significance the association between pre-test knowledge scores and selected variables were calculated using Chi square test. Conclusion : The nurse carries personnel responsibility for nursing practice and for maintaining competence by continuous learning. Video teaching programme enhance the knowledge of GNM nursing students .

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Key words: Effectiveness, Safe Handling, Cancer Chemotherapeutic Drugs, Nursing Officers, PTP.

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This study examines methods for forecasting cryptocurrency prices, focusing on Bitcoin, Ethereum, and other major cryptocurrencies. We analyze historical data, market sentiment, technical indicators, and fundamental factors to build predictive models. Additionally, we assess the influence of external factors like regulations and global events. Our research aims to enhance understanding of cryptocurrency market dynamics and provide actionable insights for investors and researchers.

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 Keywords

Cryptocurrency, Price Prediction, Bitcoin, Ethereum, Forecasting, Machine Learning, Sentiment Analysis, Technical Indicators, Fundamental Analysis, Market Dynamics, External Factors.

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Studies on neurology ward patients have demonstrated elevated prevalence of mental health disorders. Previous reports have indicated a wide range of prevalence rates (39% to 64%) of psychiatric morbidity in neurological patients, with a notable poor identification rate of mental diseases in this population. This study aims to investigate the hypothesis that the psychiatric morbidity in neurological patients may influence their disease behaviors. The research, conducted at the Government General Hospital in Guntur, India, involved 58 neurological patients who completed the self-administered Illness Behaviour Questionnaire (IBQ). The IBQ, a 62-item measure with dichotomous (Yes/No) responses, was utilized to assess various components of sickness behaviors. Importantly, interviewers were unaware of the IBQ subscale ratings. Among the participants, 31 met DSM-IIIR criteria for a mental condition, and 25% (8 patients) were diagnosed with depressive disorder (major depressive disorder or dysthymia). The study's findings suggest that neurological patients with psychiatric morbidity tend to exhibit more severe disease behaviors compared to their counterparts without psychiatric morbidity. If confirmed, these results emphasize the importance of considering the impact of mental morbidity on specific aspects of sickness behavior in the development of treatment approaches.

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Mental disorder, Psychiatry, Neurology, Depression

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To back the conveyance of persistent care, apportioning of Medicine and stock administration are vital issues. In specific, it screens and records the Patients points of interest. The Quiet will be allotted with unique-id after the enrollment completes. PMS shows the patient's individual points of interest and wellbeing reports/ therapeutic E Medicine. In conjunction with Automatic alert system i.e. the remainder will be given to Pharmacist on stock coming to least level. Electronic endorsing (e-prescribing) permits Pharmacist to arrange and send medicines electronically based on the medicine -id. It stores all charging information for apportioned medicine.

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 Keywords

Pharmacy Management System (PMS), Electronic Pharmacy Record (EPhR), Electronic prescribing.

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Creative Commons Attribution 4.0 and The Open Definition

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: High-frequency trading (HFT) is a complex and fast-paced form of automated trading that uses sophisticated algorithms to exploit tiny price discrepancies in the market. While HFT has increased market efficiency and liquidity, it has also raised concerns about fairness and potential manipulation. This research explores the evolution of HFT, its impact on market dynamics, and the challenges it poses for regulators and policymakers. By examining cases like the Italian and Swedish stock markets, the study highlights the need for adaptable regulations that can ensure a stable and fair financial system in the face of evolving automated trading practices. The knowledge gained from this research can inform policymakers, market participants, and investors as they navigate the ever-changing landscape shaped by HFT.

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High Frequency Trading, Liquidity, Implied Volatility

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Creative Commons Attribution 4.0 and The Open Definition

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College management systems play a critical role in managing the daily operations of educational institutions. With the advent of web-based systems, the management of colleges has become more efficient and effective. This survey paper provides a comprehensive overview of college management systems developed using PHP, a widely-used server-side scripting language. The paper presents an analysis of ten recent IEEE reference papers and a base paper on college management systems using PHP. This survey paper examines the different approaches, methodologies, and contributions of these papers, and identifies the factors that make an ideal college management system.

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College Admission System, Research Paper, Technical Writing, Science, Engineering and Technology.

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Creative Commons Attribution 4.0 and The Open Definition