Volume 12 | Issue 3 |

 Abstract

Cement usage has surged due to massive infrastructure projects, with 30 billion tons of cement concrete used annually to meet global demand. Scholars worldwide are devising novel carbon-neutral construction approaches to repurpose industrial pollutants, and they are disseminating their research outcomes on the internet. Bagasse from sugarcane has a high proportion of amorphous silica and can be applied to the concrete-making process. The purpose of this study is to examine the physical and chemical properties of ash made from bagasse from sugarcane. The investigation focuses on the impact of sugarcane bagasse ash processing on concrete performance. In this work, concrete treated with various concentrations of sugarcane bagasse ash (SCBA) is examined for its fresh and hardened qualities. The purpose of this study is to examine the physical and chemical properties of ash made from bagasse from sugarcane. The investigation focuses on the impact of sugarcane bagasse ash processing on concrete performance. In this work, concrete treated with various concentrations of sugarcane bagasse ash (SCBA) is examined for its fresh and hardened qualities. Recycling industrial and agricultural waste into concrete could bring in a more environmentally conscious future. In this study, Granite Waste (GW) and Sugarcane Bagasse Ash (SCBA) were examined and evaluated as possible partial substitutes for river sand. % substitution is determined by particle packing. It is studied whether river sand may be partially replaced with bagasse ash and granite debris. The concrete is put through tests such as compression and splitting

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Sugarcane Ash, Granite Waste, Fine Aggregate, Concrete, etc

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Electronic human resource management (HRM) in businesses is significantly impacted by gamification. It gives employers an opportunity to draw in and keep workers while also converting repetitive tasks into engaging activities and boosting staff productivity. HR procedures like hiring, training, adaption, motivation, performance management, and staff appraisal have all benefited from the use of gamification techniques and tools. Employee development, training costs, and engagement can all be improved by gamification in HRM systems. Employee motivation and engagement are raised, training effectiveness is increased, and employees' critical capabilities are developed and enhanced. For the purpose of hiring, gamification can also be used to draw in and evaluate qualified IT candidates. General benefits of gamification in electronic HRM include higher productivity, loyalty, and job happiness. The study of effective search tactics for SLRs in the management sciences has produced methodological patterns pertaining to transparency and replicability. An alternative method is to examine previous literature review articles on the subject matter to generate keywords, which lessens prejudice and guarantees transparency and comprehensiveness. This approach has been tried and tested in the domain of operational risk management, making it easier to come up with keywords for a multidisciplinary strategy. Furthermore, organizing a literature evaluation is crucial for expanding knowledge and choosing journals for a theoretical basis in fields like energy management. Information seekers in management research might find guidance by following a methodical approach to doing a literature search on web-based databases. The aim of the current study is to do a literature review on the topic of role of gamification in electronic human resource management.

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gamification, mini-review, and electronic human resource management

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This feasibility study investigates the integration of daily Quality of Life (QoL) assessments into routine clinical oncology practice. With the recognition of cancer treatment's multifaceted impact on patients, extending beyond conventional survival metrics, there is a growing emphasis on evaluating QoL as an essential parameter. The study aims to assess the feasibility and benefits of daily assessments, focusing on acceptance and adherence by healthcare providers, practical incorporation into electronic health records, and potential impacts on patient outcomes. Using a mixed-methods approach over a six-month period, the study collects quantitative data from daily QoL assessments and qualitative insights through interviews and surveys. Conducted at the Government General Hospital in Guntur, Andhra Pradesh, India, the study involves 15 patients, with two dropouts. The average patient age is 57, and the majority are female, diagnosed with various cancers undergoing different treatments. Results indicate that the QoL assessments, primarily utilizing the QLQ-C30 questionnaire, were completed by patients at scheduled appointments with an average completion time of 10.3 minutes. Physician assessments showed a significant improvement in perceived knowledge of patients' daily activities from baseline to the third visit. The QoL summary was deemed helpful by physicians in improving communication and obtaining essential information from patients without disrupting their routine. In conclusion, this feasibility study suggests that standardizing daily QoL evaluations in outpatient cancer clinics is practical and well-received by both patients and healthcare providers. The simplicity of the questionnaire and rapid accessibility of findings make it feasible to integrate into daily routines, potentially reshaping oncology care towards a more patient-centered and holistic approach.

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Quality Of Life (QoL), Oncology, Cancer, Patient's Outcome

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Stress is a pervasive phenomenon in modern society, and it has been strongly linked to a myriad of comorbid conditions. This comprehensive review aims to explore the intricate relationship between stress and its comorbidities, taking into account various aspects such as psychological, physiological, and behavioral factors. The review delves into the multifaceted impact of stress on mental health, including its role in the development and exacerbation of anxiety disorders, depression, and post-traumatic stress disorder. Furthermore, it uncovers the intricate interplay between stress and physical health, shedding light on how chronic stress can contributed to cardiovascular disease, immune system dysregulation, and metabolic disorders. In addition, the review examines the behavioral repercussions of stress, exploring its influence on substance abuse, addictive behaviors, and disrupted sleep patterns. Special attention is a given to the neurobiological pathways through which stress exerts its effects, including the hypothalamic- pituitary-adrenal axis and the sympathetic nervous system. Furthermore, the review discusses the important early intervention and effective stress management strategies in mitigating the risk of comorbid conditions. It highlights the role of cognitive- behavioral therapy, mindfulness-based interventions, pharmacological approaches in addressing stress and its associated comorbidities. By synthesizing evidence from diverse fields, this review presents a comprehensive understanding of the complex relationship between stress and comorbid conditions. It underscores the imperative for tailored interventions that consider the intertwined nature of stress and its comorbidities, aiming to pave the way for more effective therapeutic approaches and improved health outcomes.

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Mental health, sleep disturbances, substance abuse and addiction, chronic pain, stress and memory.

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Plants provide valuable medicinal chemicals with significant potential in the pharmaceutical sector. The study aims to determine the phytochemical composition of therapeutic plants and evaluate their antioxidant and antibacterial properties. This study was undertaken with an objective of testing the antimicrobial and antioxidative properties of Alstonia Scholaris leaves and identifying the bioactive compound . Alstonia scholaris R. Br, a part of the Apocynaceae family, is a plant utilised in conventional medicine. The research aims to qualitatively examine and compare the initial phytochemical components present in the Alstonia scholaris leaves. The qualitative Phytochemical screening indicates the existence of flavonoids, phenolic compounds, alkaloids, phenols, and tannins in the leaf extracts. Analysed the antibacterial and antioxidant activities of Alstonia scholaris leaf extracts in vitro. The antibacterial efficacy of extract of leaves was assessed using an alcoholic extract to ascertain the minimal inhibitory concentration (MIC) for both positive and negative pathogens: Staphylococcus aureus, Escherichia coli, using disk diffusion method. Methanolic extract from leaf of Alstonia scholaris showed potential antioxidant activity and antimicrobial activity. Plant extracts' antioxidant activity was assessed by FRAP. The plant extracts exhibited strong antioxidant action against FRAP. The Alstonia scholaris extracts exhibited notable antibacterial activity, with minimum inhibitory concentration (MIC) values ranging from 31.25 to 1000 ug/ml, and demonstrated bactericidal activity against all tested species. The analysed extracts of medicinal plants in our research have the potential to serve as antioxidants, antibacterial agents, and as sources for creating novel pharmaceuticals.

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Alstonia scholaris R., Microbial activity, Antioxidant activity, Agar well diffusion method

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Now-a-days, an influence of being Entrepreneur and Innovator trend is being occurred in India. This is an auspicious movement to GDP growth and for being self-reliance. This is the effect of Government support of contemporary announced schemes for motivating the people to start their businesses and showing their talent through the stand-up India scheme. As per the education rate of India, a rapid improving rate is being visualized which is the basic requirement of attaining knowledge for the surrounding happening knowledge for everyone who is engaged in this. A matrix is given by Assistant Professor Abhimanyu Gupta which is known as The SHIV Matrix; by this he postulates that Strength, Honest, Intellectuality, and Versatility are the universal characteristics of every person. According to him, if an individual focus by using these characteristics in a matrix form as per given in the work of 'SHIV' matrix then he can optimized his/her skills to generate "Optimum Confident" which is useful for the decision making process. Hence, the main theme of this lesson is "How an individual has significance of the use of the SHIV matrix for being an Omniscient Learner in the competitive era?"

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Innovator Trend, SHIV Matrix, Omniscient Learner, and Optimum Confident.

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Abstract : The endeavour of Indian women to establish themselves is approaching a significant milestone. The Government of India has acknowledged the imperative of supporting women entrepreneurs and fostering women empowerment, leading to the initiation of several schemes. These initiatives are designed not only to provide financial assistance but also to enhance women's role in the economic development of the nation. Availing these schemes is anticipated to bring about positive changes and substantially impact the businesses managed by women. The government's objective is to elevate both the economic and social standing of women through the implementation of these schemes. This paper aims to assess and evaluate the effectiveness of the policies and schemes introduced by the Government of India in this regard.

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Women entrepreneurs, PMEGP, Schemes for Women entrepreneurs.

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Abstract: Cancer is characterized by uncontrolled cell growth and acquisition of metastatic properties. Some common forms include breast cancer, lung cancer, prostate cancer, colorectal cancer, and leukemia. Despite significant advances in research and treatment modalities, cancer remains a significant public health challenge, with millions of new cases diagnosed each year. For effective cancer therapy, it is necessary to improve and develop novel strategies for effective delivery of chemotherapeutics to cancer cells. Conventional chemotherapeutic agents accumulate both in normal and tumor cells due to non-specificity. The ultimate goal of cancer therapy is to reduce systemic toxicity and improve the quality of life. The landscape of cancer treatment has improved significantly over the past four decades. Novel treatment with ONCOS-102, developed by Targovax, is a genetically modified adenovirus designed to selectively infect cancer cells in lungs and stimulate anti-tumor immune responses has been developed in recent years. New approaches, such as Photodynamic therapy(PDT) is a minimally invasive treatment that utilizes a photosensitizing agent, light, and oxygen to selectively destroy oral cancer cells. One photosensitizer that has shown promise in oral cancer treatment is 5-aminolevulinic acid of oral cancer. Immune checkpoint inhibitors, such as anti-PD-1 or anti-PD-L1 antibodies, block this interaction, thereby reactivating T cell-mediated anti-tumor immune responses in Breast cancer. With the development of molecular biology and genomics, targeted therapy research has achieved a breakthrough development, including anti-angiogenesis, immune checkpoint inhibitors, and other treatments that are efficient for treatment of cervical cancer. a novel approach to the development of AR antagonists is to target the amino-terminus domain of the AR. The small molecule AR antagonist EPI-001 inhibits protein-protein interactions necessary for AR transcriptional activity. A promising novel approach for treating gastric cancer involves targeting the human epidermal growth factor receptor 2 (HER2), which is overexpressed in approximately 20% of gastric cancers.

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- Photodynamic therapy, programmed death-ligand 1, human epidermal growth factor receptor 2, Androgen Receptor Signaling Pathway

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In recent years studies on drug utilization (DU) have become a potential tool to be used in the evaluation of health systems. Studies on the process of DU focus on factors related to prescribing, dispensing, administering and taking of medication and its associated events. DU data is available from databases - computerized or otherwise. From these databases different types of information, qualitative or quantitative or referring to a particular population are available. Patient files and computer registries are widely used as instruments for collecting information on DU. Prospective, Concurrent or Retrospective Drug utilization evaluation (DUE) may be used depending upon the timing of data collection. Importance of DUE in Pharmacoepidemiology (PE) have been increasing due to their close association to other areas like - public health, Pharmacovigilance (Pv), Pharmacoeconomics and pharmacogenetics. This review article highlights various aspects, scope, types and future perspectives of DUE.

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Drug utilization (DU), Pharmacoepidemiology (PE), Pharmacoeconomics, Data collection, Drug utilization evaluation (DUE) cycle.

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