Volume 11 | Issue 10 |

 Abstract

Increasing development in healthcare systems and availability of efficient miniaturize components or systems that are economics has led to profound scope for research in many new fields. Capsule robot was one such fictional idea that turned into factual reality because of use of applicative miniaturized components. Initially capsule robots were developed for endoscopic applications. These travel inside the gastrointestinal tract and thus capture images of the gastrointestinal tract and related areas. Later, capsule robots were developed to be used as the unique tool to construct micron and sub-micron sized drug delivery systems for target delivery and treatment. This article highlights on various aspects of capsule robots in diagnosis and therapy of various disorders and diseases, together called theranostic approach in drug delivery systems

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capsule drug; delivery; technology; innovation; digestive; gastrointestinal; capsule endoscopy

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The objective of this study is to compare the attitudes of individuals from concordant and discordant families. A total of 160 students (boys and girls) of 9th class of secondary schools (public and private) were taken as respondents. The tool used for data collection 'A survey on familial adjustment'. After the analysis of data highlights that there is significant differences in attitude between individuals from concordant and discordant families. It further reveals that gender does not significantly affect attitudes within concordant and discordant families, except for female individuals where a significant difference was observed. These findings contribute to our understanding of the relationship between family dynamics, gender, and attitudes

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A Comparative Investigation into the Impact of Family Dynamics on Attitude of Members in Concordant and Discordant Families

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In the realm of computer vision, object detection poses a significant challenge, especially in accurately localizing and categorizing objects within images. This paper introduces a novel method that utilizes a pre-trained deep learning model to detect objects in real time by processing webcam-captured images and video streams. Leveraging the renowned speed and accuracy of the YOLO algorithms, the system efficiently counts and monitors specific objects in each video frame, making it especially apt for visualization-focused applications. By integrating the YOLO model with the COCO dataset, the approach outperforms existing techniques in terms of precision and real-time responsiveness.

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Computer Vision, Object Detection, YOLO algorithm, Deep Learning, Open-CV, COCO dataset.

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The investigator make a comparative analysis of emotional adaptation in individuals from harmonious and conflicted families. A total of 80 students both from harmonious and conflicted families (boys and girls) of 9th class of secondary schools (public and private) were taken as respondents. The tool used for data collection 'A survey on familial adjustment'. After the analysis of data the result highlights that there is no significant difference between individuals of harmonious and conflicted families with regard to emotional adjustment. There is no significant difference between male and female individuals of harmonious families with regard to emotional adjustment. There is no significant difference between male and female individuals of conflicted families with regard to emotional adjustment. There is significant difference between male individuals of harmonious and conflicted families with regard to emotional adjustment at 0.01 level. There is significant difference between female individuals of harmonious and conflicted families with regard to emotional adjustment.

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A Comparative Analysis Of Emotional Adaptation In Individuals From Harmonious And Conflicted Families.

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The primary aim of this article is to introduce the Zagreba Vector Index for the chemical graphs. Here in this research article, the topological indices were partially replaced by the new approach, Vector index for graphs. The vector index is named as Zagreb vector index, and used to study the physical properties of various chemical compounds (alkanes), their structures, the correlativity with the Vector-Index. In determining the Vector index, I have used total degree of the vertex (du), as the first component of the vector along with two more components to create a vector index. In the vector index of an atom, there will be three components, the first component of the vector is it's total degree du, second component is number of similar atoms adjacent to it d1u and the third component is number of heterogeneous atoms adjacent to it d2u. After a thorough investigate, the Vector index found to be a useful tool in predicting the physical properties of lower alkanes.

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The primary aim of this article is to introduce the Zagreba Vector Index for the chemical graphs. Here in this research article, the topological indices were partially replaced by the new approach, Vector index for graphs. The vector index is named as Zagreb vector index, and used to study the physical properties of various chemical compounds (alkanes), their structures, the correlativity with the Vector-Index. In determining the Vector index, I have used total degree of the vertex (du), as the

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2020 a year which the world can't forget as COVID-19 thrash whole world. It was such a huge crisis that it effected every sector. Through this paper we will try to investigate COVID-19 impact on cryptocurrency market. As we all know cryptocurrency market is fully based on speculation with this paper, we will try to analysis the positive impact and growth of cryptocurrency market in India during covid -19 period with the help of some secondary Qualitative and quantitative data. This study will help in understanding the complexity/unpredictability of the cryptocurrency market from the bull market to the COVID-19 pandemic outbreak with the help of some financial tools and techniques.

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covid, postive,cryptocurrency,2019

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In this modern era, medicinal plants are important for the drug industries for the production of therapeutic compounds. Hence the present study was aimed at determining phytochemical analysis of leaves of locally grown Nyctanthes arbortristis, Murraya koenigii plants for their antibacterial activity against selected bacterial pathogens. For the present study, herbal extracts of leaves of Nyctanthes arbortristis and Murraya koenigii were prepared by Cold maceration method by using methanol as solvent. The antibacterial activity was determined by the agar well diffusion technique and the prepared extract was evaluated for physicochemical characters. The bioactive compounds present in the methanol extract a fraction of Nyctanthes arbortristis and Murraya koenigii leaf were identified by GCMS analysis. The maximum antibacterial activity was observed for a methanolic extract of Nyctanthes arbortristis than Murraya koenigii. Both the methanolic extracts exhibited maximum activity against the organism Staphylococcus aureus. The physicochemical characters showed the presence of carbohydrates, alkaloids, tannins, cardiac glycosides, fatty acids, and oils. The GCMS analysis showed the presence of 45 peaks indicating the presence of 45 compounds in both the methanolic extract of Nyctanthes arbortristis and Murraya koenigii. The Constituents obtained from Nyctanthes arbortristis extraction with high quantity were 2-(4-Methoxyphenyl)ethanol(10.46), Neophytadiene(10.33), n-Hexadecanoic acid(8.95) and in Murraya koenigii extraction 1-Methyl-pyrrolidine-2-carboxylic acid(41.80), Phytol(14.66), and Caryophyllene(6.50) were present in high amounts. It can be concluded that leaves of Nyctanthes arbortristis and Murraya koenigii can be used for therapeutic purposes.

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GCMS, antimicrobial activity, Nyctanthes arbortristis, Murraya koenigii, Staphylococcus aureus, Caryophyllene.

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Dengue fever is one of the most common mosquito-born diseases worldwide, affecting an estimated 390 million people per year. Over the past two decades, efforts to prevent dengue virus ( DENV) infections have faced several challenges , primarily related to the complexity of conducting long - term studies to evaluate the effectiveness and safety of exclusion vaccines and the associated risk is related to vaccine -related DHS/DSS , especially in children .At least seven DENV vaccine have progressed through various phases of clinical trials ; However ,only three of them ( Dengvaxia ,TV003 and TAK-003) have shown promising results and are discussed in detail in this review in terms of their molecule design ,efficacy and immunogenicity .Safety challenges in developing the DENV vaccine are also discussed.

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Dengu fever, mosquito born dieases,DENV,DHS/DSS, DENV vaccine.

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Parikartika is a frequently encountered anorectal ailment. Typically, Parikartika is likened to a fissure in ano due to its significant discomfort. In Ayurvedic literature, Parikartika is not classified as an independent medical condition but rather as a complication arising from various Ayurvedic therapies such as Vaman, Virechana, and Basti, as well as from certain ailments like Arsh and Atisar, and Grahani. An individual's well-being is closely tied to their dietary choices, constipation, environmental factors, and way of life. In our contemporary world, lifestyle-related disorders like hypertension, diabetes mellitus, hypothyroidism, obesity, and more are affecting a substantial portion of the global population. Anorectal disorders such as fissures in ano and hemorrhoids can be attributed to poor dietary habits and an unhealthy lifestyle. Traditional treatments for fissure in ano, as described in Ayurveda (Gudaparikartika), involve a holistic approach combining dietary modifications, lifestyle changes, and herbal therapies. Moreover, modern medical interventions, including topical medications, botulinum toxin injections, and surgical procedures like lateral internal sphincterotomy, have shown efficacy in managing chronic and recurrent fissures.

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Basti, Chhedandvat Shool, Guda, Kartanwat, Vaman, Virechana

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"Phyto" means plant and "some" means something like a cell. The pharmacokinetic and pharmacodynamic properties of phospholipid complexes are superior to traditional herbal extracts [1]. Phospholipid complexes are also known as new drugs with lipophilic complexes consisting of glycerophospholipids obtained from different plants. Phytosomes are used in phytomedicine, herbal medicines and Ayurvedic formulations [2]. It is also called Herbosome, which is a new patented technology. Phytosome or Herbosome technology increases the hydrophilicity of highly lipophilic drugs, making them suitable for drug delivery and increases the lipophilicity of hydrophilic botanical components [3]. Phytosomes are usually prepared by reacting one or two moles of polyphenolic plant components with phospholipids. T. There are many products on the market containing herbal medicine such as ginkgo biloba, milk thistle and tea tree. This review describes the latest definitions of the classification, its types, characteristics and features [4]. This article discusses the physicochemical and pharmacological properties and structures of phospholipids [5]. Phospholipids have dual solubility and act as emulsifiers. Phospholiposomal technology can serve as a bridge between new and traditional delivery systems [6]. Phospholipomas are a new drug delivery method based on phytochemistry. In addition to improving the processing of many plant compounds, they also have better absorption and higher bioavailability [7]. Plant ingredients have been used in medicine since ancient times due to their pharmacological effects [8].

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Phytosomes, liposomes, bioavailability, new drug delivery systems (NDDS), phospholipids, plant ingredients.

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