Volume 9 | Issue 10 |

 Abstract

Heterocyclic compounds can be used as therapeutic agents. Indole is an important class of heterocyclic compound containing nitrogen with wide variety of biological activities. Isatin is a derivative of indole which is indole-2, 3 Dione. Isatin is reported for anti- tubercular activity. Quinoline is also reported for various biological activities. So, a scheme was designed and isatin incorporated quinoline hybrids were prepared to improve biological activity. In the present research isatin incorporated quinoline (7a, 7b, 7c and 7d) were prepared, and were characterized by using TLC, IR, NMR and MASS spectral data. They were evaluated for anti-tubercular activity. Among those derivatives, compound 7a and 7b showed good activity.

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 Keywords

Isatin, synthesis, aniline, heterocyclic, moiety

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Creative Commons Attribution 4.0 and The Open Definition

 Abstract

Abaqus/FEA was developed originally to solve complex problems by numerical methods in solid mechanics. FEA is the most widely used and versatile technique for simulating deformable solids. This paper gives an overview of the Abaqus software which is required to understand the FEA implementation for solid mechanics' problems. The physical behaviours of mechanical structures or systems are analysed, and the minimum potential energy principle is used to develop element models. The procedures for FEA modelling are discussed for a few of classic solid mechanics' problems such as foundation, plane stress, plane strain, modal analysis, as well as fatigue analysis.

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 Keywords

FEA, Modal analysis, Abaqus, foundation.

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Creative Commons Attribution 4.0 and The Open Definition

 Abstract

The study showed that a highly significant difference in life satisfaction among single and married (double) aged females was existing whereas no significant difference was observed among single and married (double) aged males. Type of family has also not affected the life satisfaction of aged persons. Regarding impact of education on life satisfaction of aged persons, it was found that it had no effect on their life satisfaction.

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 Keywords

life satisfaction, aged persons, single and married persons

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Creative Commons Attribution 4.0 and The Open Definition

 Abstract

There is a unanimous agreement as to the severity of losses caused due to covid-19 pandemic across the various industrial sectors on global platform. Numerous factors from multitude of angles have produced this economic harm. These factors can be well attributed to the demand as well as supply side. Barring a few sectors like healthcare, almost all the industries have faced the downturn. It has impacted all the modes of mobility as well. No wonder that the Indian economic scenario has also followed the league. The paper talks about the impact of pandemic on the taxi service providers in India. The paper primarily focuses on the online taxi services industry in India and its tryst with the pandemic. The major aim is to synthesize and summarize the marketing strategies, which were adopted by the online taxi businesses to tide over the hurdles caused by the pandemic.

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COVID-19 pandemic, taxi industry, online taxi providers, App based Taxi Services, Ola, Uber

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Creative Commons Attribution 4.0 and The Open Definition

 Abstract

Background: Several activities in day to day involving upper limb require good hand grip strength. A reliable evaluation of hand grip forms an integral part of rehabilitation, not only to assess the strength muscles involves in gripping but also to apply as a tool in rehabilitating patients with variable level of hand injuries. Various sports require some degree of grip strength which improves the performance and play a key role in preventing overall injuries relevant to forearm and hand. Since the hand grip is considered to be affected by variation in carrying angle. The acute angle produced medially when the axis of the forearm deviates laterally from the long axis of the humerus, with the arm extended and palm facing forward, is referred as carrying angle. Average value of carrying angle in male is 5-10 and slightly greater in female being 10-15. If this angle is >15 it is called cubitus valgus whereas if it is <5 it is called cubitus varus.

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Background: Several activities in day to day involving upper limb require good hand grip strength. A reliable evaluation of hand grip forms an integral part of rehabilitation, not only to assess the strength muscles involves in gripping but also to apply as a tool in rehabilitating patients with variable level of hand injuries. Various sports require some degree of grip strength which improves the performance and play a key role in preventing overall injuries relevant to forearm and hand. Since

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Creative Commons Attribution 4.0 and The Open Definition

 Abstract

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Creative Commons Attribution 4.0 and The Open Definition

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Keywords: Child, Juvenile Delinquency, Juvenile Justice Laws in India, Remand room

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Creative Commons Attribution 4.0 and The Open Definition

 Abstract

Flurbiprofen is a minimal solubility, greater permeability non-steroidal anti-inflammatory medication classified as BCS class II drug. To enhance the drug's physicochemical properties, pharmaceutical co-crystals of Flurbiprofen were made with arginine as the co-crystal former. Flurbiprofen co-crystals were successfully prepared using the solvent drop grinding process. IR spectroscopy, differential scanning calorimetry, and X-ray diffraction were used to validate the integrity and uniformity of all proposed crystal structures. When compared to pure active pharmaceutical component, co-crystals with arginine exhibited a greater powder dissolving rate (API). When compared to the pure active pharmaceutical ingredient, co-crystals of flurbiprofen with arginine demonstrated a 5.2 times gradual increase in solubility. Co-crystals are an evolving approach for modifying and enhancing physicochemical aspects of drugs to improve their medicinal effects, as per the research.

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Flurbiprofen Co-crystals, Co-crystals, Cocrystalisation, Flurbiprofen.

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Creative Commons Attribution 4.0 and The Open Definition

 Abstract

Minimizing the cost of stabilization and improving the swell-shrink behavior & strength of expansive soils are major concerns to geotechnical engineers dealing with construction project over problematic soils. Expansive soil has tremendous strength but it become soft when came into contact with water, it expands during wet condition and shrinks in dry condition because of its mineralogical composition. The stability of structure is majorly influenced by expansive soils. Structures failures due to swell-shrink behavior of expansive soil are reported by many countries. This project is to improve the behavior of such soil by chemical stabilization using Fly Ash and Corex slag and Blast Furnace Slag - industrial waste used to mitigate the problems associated with expansive soil, as well as to solve the disposal problem caused by this waste which is a big environmental issue now a days, considering sustainable approach.

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 Keywords

Fly Ash, Corex Slag, soil stabilizer, soaked California bearing ratio

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Creative Commons Attribution 4.0 and The Open Definition

 Abstract

अनुवादित मराठी पुस्तकांचा इतिहास पाहिला तर खूप पूर्वीपासून मराठीत अनुवाद होत आलेले आहेत. रामायण-महाभारत सारख्या पुराणकथा किंवा महाकाव्य, ज्ञानेश्वरी, संस्कृत नाटकं, उपनिषदांमधील कथा, हॅरी पॉटर, अरेबियन नाईट्स, पंचतंत्र, इसापनीती, हॅम्लेट असे विविध माहितीपर, ऐतिहासीक, तत्त्वज्ञानविषयक, कलाविषयक, अध्यात्मविषयक, मूळ इंग्रजीतील दर्जेदार वाङमय असे अनुवादित स्वरूपातील साहित्य आपल्या मातृभाषेतून वाचताना अधिक सहज वाटते.

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प्रा. द. पं. जोशी यांचे अनुवादाचे वेगळेपण

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Creative Commons Attribution 4.0 and The Open Definition

 Abstract

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Creative Commons Attribution 4.0 and The Open Definition

 Keywords

Low birth weight, normal birth weight, cognitive ability, Full scale Intelligence Quotient.

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Creative Commons Attribution 4.0 and The Open Definition