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Paper Title: STUDIES ON DESIGN AND IN VITRO CHARACTERIZATION OF MODEL DRUG ATENOLOL CONTAINING FLOATING TABLETS USING GUAR GUM AND HYDROXY PROPYL METHYL CELLULOSE
Author Name(s): VINOD M, Dr. Rakesh Kumar Jat
Published Paper ID: - IJCRT2101001
Register Paper ID - 201843
Publisher Journal Name: IJPUBLICATION, IJCRT
DOI Member ID: 10.6084/m9.doi.one.IJCRT2101001 and DOI :
Author Country : Indian Author, INDIA, INDIA , VIjayapura, INDIA , | Research Area: Pharmacy Published Paper URL: http://ijcrt.org/viewfull.php?&p_id=IJCRT2101001 Published Paper PDF: download.php?file=IJCRT2101001 Published Paper PDF: http://www.ijcrt.org/papers/IJCRT2101001.pdf
Your Paper Publication Details:
Title: STUDIES ON DESIGN AND IN VITRO CHARACTERIZATION OF MODEL DRUG ATENOLOL CONTAINING FLOATING TABLETS USING GUAR GUM AND HYDROXY PROPYL METHYL CELLULOSE
DOI (Digital Object Identifier) :
Pubished in Volume: 9 | Issue: 1 | Year: January 2021
Publisher Name : IJCRT | www.ijcrt.org | ISSN : 2320-2882
Subject Area: Pharmacy
Author type: Indian Author
Pubished in Volume: 9
Issue: 1
Pages: 1-13
Year: January 2021
Downloads: 1692
E-ISSN Number: 2320-2882
Abstract
The present research study was aimed to develop a floating tablets containing atenolol as a model drug by using natural polymer guar gum (GG) and hydroxyl propyl methyl cellulose (HPMC). The atenolol floating tablets were prepared by direct compression technique based on effervescent approach using sodium bicarbonate as a gas generating agent. The prepared tablets were evaluated for weight variation, hardness, friability, drug content, tablet density, floating lag time, total floating time and in vitro release studies. The effect of combination (1:1) of polymers GG and HPMC proportion on in vitro drug release profile was evaluated. The floating lag time and total floating time of all the formulations were increased by increasing polymers concentration. The formulations containing sodium bicarbonate 40 mg per tablet showed desired buoyancy. The in vitro studies revealed that, the atenolol release could be sustained upto 24 by increasing the proportion of GG and HPMC mixture. Further, the floating tablet containing 35% of mixture of HPMC (17.50%) and GG (17.50%) in the ratio 1:1 with an average tablet weight of 400mg released 98.23% at the end of 24 hours was found to be suitable for successfully sustaining the atenolol release upto 24h in physiological environment of stomach and to improve the patient compliance. The FTIR spectra confirms that there is no interaction between drug and tablet excipients.
Licence: creative commons attribution 4.0
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Keywords
Floating drug delivery system, sustained release, guar gum, antihypertensive and atenolol.
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Paper Title: A STUDY ON E-LEARNING USING SWAYAM (MOOCS)- AWARENESS AMONG UNDER GRADUATE AND POST GRADUATE STUDENTS
Author Name(s): RAHUL S MOHILE
Published Paper ID: - Both payment failed
Register Paper ID - 202295
Publisher Journal Name: IJPUBLICATION, IJCRT
DOI Member ID: 10.6084/m9.doi.one.Both payment failed and DOI :
Author Country : Indian Author, India, 401602 , DAHANU, 401602 , | Research Area: Social Science All Published Paper URL: http://ijcrt.org/viewfull.php?&p_id=Both payment failed Published Paper PDF: download.php?file=Both payment failed Published Paper PDF: http://www.ijcrt.org/papers/Both payment failed .pdf
Your Paper Publication Details:
Title: A STUDY ON E-LEARNING USING SWAYAM (MOOCS)- AWARENESS AMONG UNDER GRADUATE AND POST GRADUATE STUDENTS
DOI (Digital Object Identifier) :
Pubished in Volume: 9 | Issue: 1 | Year: January 2021
Publisher Name : IJCRT | www.ijcrt.org | ISSN : 2320-2882
Subject Area: Social Science All
Author type: Indian Author
Pubished in Volume: 9
Issue: 1
Pages: 1785-1789
Year: January 2021
Downloads: 3006
E-ISSN Number: 2320-2882
Abstract
Licence: creative commons attribution 4.0
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Call For Paper December 2025
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December 2025
Volume 13 | Issue 12
Last Date :
31-Dec-2025
Submit Manuscript Online Impact Factor: 7.97 Review Results : Within 02-03 Days Paper Publication : Within 02-03 Days
December 2025
Volume 13 | Issue 12
Last Date :
31-Dec-2025
Submit Manuscript Online Impact Factor: 7.97 Review Results : Within 02-03 Days Paper Publication : Within 02-03 Days
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ISSN: 2320-2882 Impact Factor: 7.97 and ISSN APPROVED Journal Starting Year (ESTD) : 2013
ISSN and 7.97 Impact Factor Details
ISSN: 2320-2882 Impact Factor: 7.97 and ISSN APPROVED Journal Starting Year (ESTD) : 2013
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