Volume 10 | Issue 1 |

 Abstract

Loperamide hydrochloride is a common antidiarrheal drug and due to its poor aqueous solubility absorbed very slowly and erratically after oral administration. To enhance its solubility, dissolution rate self microemulsifying drug delivery system (SMEDDS) was formulated and evaluated. The solubility of loperamide hydrochloride was determined in various vehicles. Pseudoternary phase diagrams were evaluated for microemulsification existence area, and the release rate of loperamide hydrochloride was investigated using an in vitro dissolution test. SMEDDS formulations were tested for microemulsifying properties and the resultant microemulsions were evaluated for clarity, precipitation and particle size distribution. Formulation development and screening was done based on results obtained from phasediagrams and characteristics of resultant microemulsion. The optimized formulation was studied for in vitro study and was found that the formulation containing Labrafac CC (28.5%), Tween 60 (53.64%) propylene glycol:ethanol (1:1) showed a complete release in 30 minutes as compared with the pure drug which showed a limited dissolution rate. The stability studies found that the formulations were stable over period of 3 months. Thus the study confirmed that the SMEDDS formulation can be used as a possible alternative to traditional oral formulation of loperamide hydrochloride to improve its solubility and dissolution rate

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 Keywords

Self microemulsifying drug delivery systems; Loperamide hydrochloride; Pseudoternary phase diagram.

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Creative Commons Attribution 4.0 and The Open Definition

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ABSTRACT: Writing is a fundamental skill which is useful in the day to day functioning of any literate person. It is an art to express oneself to larger audience, it helps the reader learn and educate. This paper deals with the writing process, the styles of writing and the nuances of writing a good script.

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Creative Commons Attribution 4.0 and The Open Definition

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Writing skill, draft, revising, editing, proof reading, descriptive, narrative, persuasive

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Blackout is the most dreaded events in any power system. All LDCs & Utilities are combining their efforts to avoid the occurrence of blackout. In case of blackout occur effective measures & ancillary services are in place for restoring the system within minimum possible time. Mock black start drills and learning sessions on the subject familiarize the operators with the system recovery procedures, build their confidence to respond to contingencies and provide them an opportunity to address systemic deficiencies detected during the exercise. Tata power has carried out partial actual blackstart exercise with Tata hydro stations successfully in presence of RLDCs. These efforts ultimately reduce the time taken during actual system restoration and help in improving the coordination between various agencies. This paper describes the philosophy adapted during actual black start drills and Innovation practices adapted to reduce restoration time..

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Creative Commons Attribution 4.0 and The Open Definition

 Abstract

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Creative Commons Attribution 4.0 and The Open Definition

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Governance, Institution, Marginalization, Patriarchy

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Creative Commons Attribution 4.0 and The Open Definition

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Creative Commons Attribution 4.0 and The Open Definition

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: Print Journalism, News Media, Work Experiences, Personal Experiences, Professionalism

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Tantra is an important system of Indian philosophy and its close affinity to the Vedas is apparent. The Tantra scriptures themselves contain references to its Vedic origin. In this subsequent development, however, Tantra shows a more pronounced influence of the Upanisads, as well as of Yoga and the Puranas. The ritualistic worship of modern Hinduism has been greatly collared by Tantra, and this fact is particularly noticeable in Bengal, Kashmir, Gujarat, and Kerala. Saivism is an ancient Indian faith in the broad sense of the term.

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 Keywords

Mahabharata (MB), Rgveda (RV), Yajurveda (YV), Vajasaneyisamhita (VSa), Taittiriyasamhita (TSa), Kasmir Saivism (ks), Brahmamimamsabhasya (Bmb), SiddhantaSaivism (SS)

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Creative Commons Attribution 4.0 and The Open Definition

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Queer theory, homophobia, gender identity, heteronormativity

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Agricultural crop land suitability assessment of Thanjavur District is the primary objective of this study. In the present study, the remote sensing and geographic information system (GIS) techniques are utilized to assess the land type suitable for crops production. The various land capability parameters are chosen such as topographic wetness index (TWI), land use and land cover (LULC), soil, drainage density, slope, aspect and geology. All these factors determine the suitability of a given area for a particular type of crop cultivation. The various agricultural crop produce in Thanjavur district are paddy, maize, wheat, potato, and oilseed etc. All the parameters were prepared and integrated with the help of weighted overlay analysis in ArcGIS software. The final suitability maps are categorized into five classes such as not suitable zone, poorly suitable zone, moderate suitable zone, highly suitable zone and Very high suitable zone. The not suitable zone cover 27 sq.km (1%), poorly suitable zone covers 292 sq.km (8%), moderately suitable zone covers 1196 sq.km (32%), highly suitable zone covers 1596 sq.km (43%) and very high suitable zone covers 624 sq.km (17%). The result revealed that only 17% of Thanjavur district falls under very high suitability class, so it is necessary to improve the soil quality parameters to sustainable agricultural practices in the study area.

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 Keywords

Land capability, TWI, sustainable agriculture, Weightage Overlay, Thanjavur district

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Creative Commons Attribution 4.0 and The Open Definition

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Polycystic ovary syndrome (PCOS), Women in India,

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 Abstract

In the early period Buddhist Education was restricted inside the religious communities and just for the individuals from the monasteries. In any case, later on it was available to the mass, even laypeople got extension to have instruction in the establishments known as monastries. Buddhist Education turned out to be totally open and accepted individuals of varying backgrounds. The point of Buddhist Education is to change an incautious to insightful, monster hood to Buddha hood. Caste based discrimination was prevalent in India at the time when Buddha arrived. This separation was assigned to a person from the birth itself. Broadly speaking, at that time there were four divisions of whom Brahman was predominant. They delighted in privileges for strict preparation and instruction. However, other class of individuals were denied of these privileges by their strict and instructive privileges. Buddhism appeared in around 600 B.C. Buddhism and Jainism were branch-offs of Hinduism. As there was little change in their goals of life, the idea of training additionally experienced just a shift of accentuation. There was no water tight compartment in the domain of thought isolating Brahmanism, Buddhism and Jainism. They all contributed agreeably to the improvement of culture overall and their commitments to training were inseparably stirred up. The imaginative vein of the age was reflected in the field of training and culture. As knowledge became wide spread, quest for knowledge was also undertaken in a more scientific manner. The Buddhist Education presumably changed particularly in various nations and at various occasions. We get an important image of Buddhist training as it existed in India from the records left by specific Chinese Buddhist researchers, who visited India in the fifth and seventh hundreds of years of this period. The present research paper focuses on the purpose, curriculum and methodology of Buddhist education in India at that time.

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 Keywords

Dharma, Buddhism, Monastery, Meditation, Monks, University.

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Creative Commons Attribution 4.0 and The Open Definition