Published Paper Details:

Abstract: Fast dissolving oral films are key for researcher in pharma field, it is the most recent and advanced form of oral solid dosage form due to more comfort and flexibility. Over the past few decades, researcher create attraction and improve to innovative drug delivery systems, there has been increased interest for innovative drug delivery system to improve the efficacy safety, and patient compliance. For discover and develops new chemical entity is a very complex, expensive and take more time i.e. time consuming process. Anybody wants to improve and develops existing drugs and designing and developing recent innovative drug delivery systems. From of those, drug delivery system being very eminent among pediatrics and geriatrics is orally disintegrating films (ODFs). It improve the efficacy of Active pharmaceutical ingredients by dissolving within minute in oral cavity after the contact with less saliva as compared to fast dissolving tablets, without chewing and no need of water or any liquid for administration. These films have valuable superiority over fast disintegrating tablets as the latter are associated with the risks of choking and friability. This drug delivery system has various advantages over conventional fast disintegrating tablets as they can be used for dysphasic and schizophrenic patients and are taken without water due to their ability to disintegrate when it comes in contact with saliva within a few seconds releasing medication in mouth. Various approaches are employed for manufacturing of ODFs and, from which solvent casting and spraying methods are largely used. Mostly, hydrophilic polymers i.e. water loving polymers along with other excipients are used for preparing ODFs which allow films to carry out quickly disintegration and releasing incorporated active pharmaceutical ingredient (API) within seconds. Generally, Intra-gastric, sublingual or buccal route of administration also has been used for local action. Fast dissolving oral films are found to be good enough for a particular need in many situations like allergic conditions, cold and cough, nausea, sore throat, , pain, mouth ulcers, CNS disorders and CVS disorders. The main objective of this present review attempts to focus on benefits, composition, approaches for formulation and evaluation of ODFs. Orally disintegrating films have valuable and play a key role for business and market exploitation because of their valuable of benefits over orally disintegrating tablets.