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INTERNATIONAL JOURNAL OF CREATIVE RESEARCH THOUGHTS - IJCRT (IJCRT.ORG)
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ISSN Approved Journal No: 2320-2882 | Impact factor: 7.97 | ESTD Year: 2013
Call For Paper - Volume 12 | Issue 7 | Month- July 2024
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Paper Title
ISOLATION, CHARACTERIZATION AND BIOLOGICAL ACTIVITY OF FLAX LECTIN
Authors
Dr Suma TK, Vasudha TK, Dr BK Manjunath, Raghavi G, Rajalakshmi V
Keywords
flax, lectin, hemagglutination, carbohydrate binding, anti-oxidant
Abstract
Lectins are a class of non-covalent carbohydrate-binding proteins of non-immune origins; possessing at least one non-catalytic domain, they can reversibly recognize and bind to monosaccharides or oligosaccharides. Legume lectins have been demonstrated to possess antifungal and antiproliferative potency on tumor cells. Seed lectin from Linumusitassimum (flax) was extracted and partially purified by acetone precipitation followed by DEAE-cellulose ion exchange chromatography and Sephadex G-100 gel filtration chromatography. Carbohydrate binding specificity of lectin was determined by the hemagglutination method and found to be specifically binding to N-acetyl galactosamine. Purified lectin was characterized for their biological activity like antiproliferative, antioxidant, anti-inflammatory and antimicrobial activity using in vitro assays and found to possess significant biological activities.
IJCRT's Publication Details
Unique Identification Number - IJCRTOXFO020
Paper ID - 190037
Page Number(s) - 104-111
Pubished in - Volume 6 | Issue 2 | APRIL 2018
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Publisher Name - IJCRT | www.ijcrt.org | ISSN : 2320-2882
E-ISSN Number - 2320-2882
Cite this article
Dr Suma TK, Vasudha TK, Dr BK Manjunath, Raghavi G, Rajalakshmi V, "ISOLATION, CHARACTERIZATION AND BIOLOGICAL ACTIVITY OF FLAX LECTIN", International Journal of Creative Research Thoughts (IJCRT), ISSN:2320-2882, Volume.6, Issue 2, pp.104-111, APRIL 2018, Available at :http://www.ijcrt.org/papers/IJCRTOXFO020.pdf
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ISSN: 2320-2882 Impact Factor: 7.97 and ISSN APPROVED Journal Starting Year (ESTD) : 2013
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ISSN: 2320-2882 Impact Factor: 7.97 and ISSN APPROVED Journal Starting Year (ESTD) : 2013
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