Published Paper Details:

Although prior research has frequently disregarded the effects of the pregnant uterus's mechanical constriction of the left renal vein, preeclampsia poses major health hazards to both mothers and infants. This work used two different approaches: first, it investigated the relationship between elevated blood pressure and renal damage and constriction of the left renal vein in mice. Secondly, it developed an automated version of the supine pressor test (SPT) to help pregnant women determine their preeclampsia risk. The results of the study conducted on mice suggested that acute renal failure and a considerable rise in blood pressure could be brought on by persistent renal vein stenosis. From a human perspective, the research noted that when non-pregnant women switched from sleeping on their left side to resting on their back, proving that expectant mothers were capable of doing the SPT on their own. In conclusion, this study provides a promising technique for the early diagnosis of preeclampsia in pregnant women and illuminates possible underpinnings of the condition.