Published Paper Details:

Palmoplantar psoriasis (PP) is a type of psoriasis that develops on the palms and soles; however, the disease can be associated with many different morphologic patterns, including predominantly pustular lesions to thick scaly, hyperkeratotic plaques, or an overlapping of both of them. Psoriasis is an inflammatory, proliferative, chronic skin disease in which there are scaly papules and plaques that can involve any part of the body. Studies reveal that 2-3% of people have psoriasis, and 3-4% of those with psoriasis also have palmoplantar psoriasis. You can get palmoplantar psoriasis at any age. Human leukocyte antigen (HLA) Cw6 is the most often found genetic component linked to palmoplantar psoriasis. On the palms and soles, psoriasis can manifest as pustulosis, less well-defined plaques that resemble hyperkeratotic eczema, or typical scaly areas that can be scratched to reveal a fine silvery scale. It is crucial to distinguish palmoplantar psoriasis from other morphologically similar disorders such as hyperkeratotic eczema, dermatophytosis, and contact dermatitis, as the former may go undiagnosed. Usually unilateral, dermatophytosis is amenable to antifungal therapy. Psoriasis and hyperkeratotic eczema can occasionally be difficult to differentiate from one another. Underreported is the prevalence of palmoplantar psoriasis. In actuality, it is leading the race. Additional research is necessary to confirm the evolving situation.