Published Paper Details:

This study focuses on the formulation and evaluation of an antifungal cream incorporating fenugreek seed extract, neem oil, coconut oil, and clove oil, with the aim of assessing its efficacy against Aspergillus Niger. These natural ingredients were chosen for their known antifungal properties, making them promising candidates for an alternative treatment approach. To achieve this, extracts were prepared at different ratios, employing an appropriate solvent system. The resulting mixture underwent rigorous testing against a standard Aspergillus Niger strain, utilizing the agar plate diffusion method. The zones of inhibition around the agar plates containing the formulated mixture were measured, and the information achieve was exposed for statistical investigation. The antifungal activity of the prepared mixture revealed significant inhibition of Aspergillus Niger growth, as evidenced by distinct zones of inhibition. Importantly, the size of these inhibition zones varied based on the specific ratios of fenugreek seed extract, neem oil, coconut oil, and clove oil. Notably, a unique combination of these components demonstrated the highest antifungal activity. Comparative analysis against a positive control, representing conventional antifungal treatment, indicated comparable or even superior effectiveness in reducing Aspergillus Niger growth. This suggests that the formulated mixture could serve as a potent natural antifungal agent. The combined effect of fenugreek seed extract, neem oil, coconut oil, and clove oil showcased remarkable antifungal properties, opening avenues for their potential application as an alternative treatment for Aspergillus Niger fungal infections. The study proposes that the synergistic action of these four components could offer a compelling option for managing such infections. While the results are promising, the study acknowledges the need for further investigations to delve into the underlying mechanisms of action. Additionally, assessing the effectiveness and safety of this formulation in vivo through extended research and clinical trials is imperative. The reading is funding in the rising body of knowledge on likely anti-fungal agents also presents a potential avenue for innovative fungal infection treatments.