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INTERNATIONAL JOURNAL OF CREATIVE RESEARCH THOUGHTS - IJCRT (IJCRT.ORG)
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ISSN Approved Journal No: 2320-2882 | Impact factor: 7.97 | ESTD Year: 2013
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Published Paper Details:
Paper Title
Agmatine a Novel Neurotransmitter: A General Review
Authors
Sagar Bawankar, Rupali deshmukh, Dipak Lilhare, Pallavi Bisen, Pallavi Katre
Keywords
Keywords1. Agmatine, Neurotransmitter, CNS (Central Nervous System), Pharmacological role,Imidazoline-binding, Neurological disorders, Neuroprotective effects, Pain modulation, Antidepressant effects, Neuroinflammation, Cognitive enhancement, Cardiovascular health, Metabolic hormone regulation, Safety and efficacy, Combination therapies
Abstract
Abstract:The aim of this study was to assess the role of agmatine as a novel neurotransmitter in the CNS and its other important actions in the body. The CNS, being the most injury-susceptible part of the mammalian body, has been observed to protect neurons from damage. Agmatine plays a vital role in neurological diseases. Previous studies have found that agmatine is related to the regulation of nitric oxide synthesis, relief from chronic pain, cerebral edema, and glucose regulation. It binds with imidazoline-binding sites and ?2-adrenoreceptors and blocks N-methyl-D-aspartate receptors via voltage and concentration-dependent mechanisms, as well as other ligand-gated cationic channels including nicotinic and 5-HT3 receptors. In this review, we will focus on the pharmacological role of agmatine, establishing it as a novel neurotransmitter.
IJCRT's Publication Details
Unique Identification Number - IJCRT24A4524
Paper ID - 257940
Page Number(s) - n234-n240
Pubished in - Volume 12 | Issue 4 | April 2024
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Publisher Name - IJCRT | www.ijcrt.org | ISSN : 2320-2882
E-ISSN Number - 2320-2882
Cite this article
Sagar Bawankar, Rupali deshmukh, Dipak Lilhare, Pallavi Bisen, Pallavi Katre, "Agmatine a Novel Neurotransmitter: A General Review", International Journal of Creative Research Thoughts (IJCRT), ISSN:2320-2882, Volume.12, Issue 4, pp.n234-n240, April 2024, Available at :http://www.ijcrt.org/papers/IJCRT24A4524.pdf
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ISSN: 2320-2882 Impact Factor: 7.97 and ISSN APPROVED Journal Starting Year (ESTD) : 2013
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ISSN: 2320-2882 Impact Factor: 7.97 and ISSN APPROVED Journal Starting Year (ESTD) : 2013
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