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INTERNATIONAL JOURNAL OF CREATIVE RESEARCH THOUGHTS - IJCRT (IJCRT.ORG)
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ISSN Approved Journal No: 2320-2882 | Impact factor: 7.97 | ESTD Year: 2013
Call For Paper - Volume 12 | Issue 7 | Month- July 2024
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Published Paper Details:
Paper Title
A Review: Modeling of selected protein structure from NCBI database using BLAST & FASTA
Authors
Swati Gupta, Ashutosh Saini
Keywords
Protein, Insulin, BLAST, FASTA.
Abstract
Insulin is a small globular protein hormone that consists of two polypeptide chains, A and B, that are connected by two disulfide bonds. The A chain is composed of 21 amino acids, while the B chain is composed of 30 amino acids. The two chains are held together by a third disulfide bond between the A7 cysteine residue and the B7 cysteine residue. The tertiary structure of insulin is stabilized by a network of hydrogen bonds, salt bridges, and hydrophobic interactions between the amino acid residues. The hormone also contains a hydrophobic core that is responsible for its stability and solubility. The insulin molecule adopts a compact conformation that allows it to fit into its receptor on the cell surface. Alterations in the structure of insulin, such as mutations or chemical modifications, can affect its biological activity and lead to insulin resistance or other metabolic disorders.
IJCRT's Publication Details
Unique Identification Number - IJCRT24A4499
Paper ID - 258113
Page Number(s) - n16-n26
Pubished in - Volume 12 | Issue 4 | April 2024
DOI (Digital Object Identifier) - http://doi.one/10.1729/Journal.39237
Publisher Name - IJCRT | www.ijcrt.org | ISSN : 2320-2882
E-ISSN Number - 2320-2882
Cite this article
Swati Gupta, Ashutosh Saini, "A Review: Modeling of selected protein structure from NCBI database using BLAST & FASTA", International Journal of Creative Research Thoughts (IJCRT), ISSN:2320-2882, Volume.12, Issue 4, pp.n16-n26, April 2024, Available at :http://www.ijcrt.org/papers/IJCRT24A4499.pdf
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ISSN: 2320-2882 Impact Factor: 7.97 and ISSN APPROVED Journal Starting Year (ESTD) : 2013
ISSN and 7.97 Impact Factor Details
ISSN: 2320-2882 Impact Factor: 7.97 and ISSN APPROVED Journal Starting Year (ESTD) : 2013
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