Published Paper Details:

Nanoemulsions have emerged as a promising approach to enhance the solubility, stability, and bioavailability of bioactive compounds derived from natural sources. In this study, we aimed to develop a nanoemulsion formulation incorporating extracts from Camellia sinensis (green tea) and Bombax ceiba (silk cotton tree), two plants known for their diverse pharmacological properties. The nanoemulsion was prepared using high-pressure homogenization techniques, and its physicochemical properties, including particle size, zeta potential, and stability, were characterized. The nanoemulsion was prepared using high-pressure homogenization technique and characterized for its physicochemical properties including particle size, zeta potential, and stability. The optimized nanoemulsion exhibited a uniform particle size distribution with an average diameter in the nanometer range, indicating its suitability for enhanced drug delivery. Moreover, the zeta potential analysis revealed sufficient electrostatic repulsion among the droplets, ensuring physical stability against aggregation and sedimentation. The nanoemulsion demonstrated enhanced solubility and permeability of bioactive components, leading to improved bioavailability compared to conventional formulations. Furthermore, synergistic effects between Camellia sinensis and Bombax ceiba extracts were observed, suggesting potential multifaceted health benefits. Overall, the developed nanoemulsion holds promise for various applications in pharmaceuticals, cosmeceuticals, and functional foods, offering improved stability, enhanced bioavailability, and potential synergistic effects. Further research is warranted to explore its efficacy in preclinical and clinical studies and to optimize formulation parameters for specific applications.