Published Paper Details:

This study aims to assess the quality parameters of Clopidogrel tablets from different manufacturers available in the Bangladeshi market. Clopidogrel is a potent antiplatelet and antithrombotic drug.This study aims to conduct a comprehensive quality control assessment of different brands of Clopidogrel tablets available in the market.Clopidogrel is a potent anti-platelets and antithrombotic drug. It is film coated and 75 mg tablet. The objective of our study was to evaluate the quality parameters of some marketed clopidrogel tablet and to compare the parameters among them.To assess the quality, nine different marketed clopidogrel 75 mg tablet were selected and in-vitro dissolution test, potency, disintegration time were carried out.[2] Other general quality parameters of these tablets like weight variation, hardness, friability were also determined according to established protocols. All the brands comply the requirements of ''Indian Pharmacopoeia'' as they showed acceptable weight variation range.Friability of all brands was less than 1%. No significant differences were founding disintegration time as they disintegrated within 15 minutes. In case of dissolution profile all brands showed better dissolution time as they released more than 75% of drug in 45 minute. The hardness of one brand was within the range 40-60N. The limitation of the potency must be within 95-105%.