Published Paper Details:

Introduction: Beta thalassemia syndromes are the group of disorder which is hereditary (Autosomal recessive)with characterized by reduced or absent beta globin chain synthesis resulting in the reduced hemoglobin in Red blood cell(RBC), Decreased RBC production and anemia. Material and Methods: We studied on the 50 patients attending the blood bank for transfusion from the pediatric department of C.U.Shah medical College and hospital, Surendranagar from the October 2022 to September 2023. Aims and objectives: To determine the age of patients, at the age when they diagnosed , frequency of transfusion, total number of transfusions till the study done and correlation with The serum ferritin level, and hemoglobin level and MCHC is also studied from records. Result: Among 50 patients, mean age is 9.48years, with the mean duration 8.25 years till study done having mean hemoglobin up to 7.04gm/dl, mean level of MCHC is 36.48g/dl, due to once or twice a month transfusion to maintain the serum ferritin level, majority are on the chelation therapy (96%), mean Serum ferritin level is correlated with the number of transfusion in <150 is 2948+1745.69 and in >150 is 3100+1365.42 microgram/dl. Male to female ratio is 1.38 in the study done. Conclusion: It is mandatory to monitor the duration of disease hemoglobin level, serum ferritin level with the transfused units in beta thalassemia major patients to give them better and prolonging life expectancy