Published Paper Details:

This study aimed to develop a novel sol-gel formulation of Giloy (Tinospora cordifolia) for topical application, leveraging its therapeutic potential in dermatological conditions. The sol-gel system offers advantages such as improved stability, enhanced bioavailability, and prolonged release of active compounds. Various formulations were prepared and characterized for rheological properties, drug content, pH, and spreadability. Additionally, in vitro release studies were conducted to assess the drug release profile. The optimized formulation demonstrated desirable rheological properties, satisfactory drug content, and appropriate pH for skin application. Moreover, the in vitro release study revealed sustained release characteristics, indicating its potential for prolonged therapeutic action. Further in vivo studies are warranted to evaluate the efficacy and safety of the developed Giloy sol-gel formulation for topical use. This research signifies a promising approach in utilizing natural remedies for dermatological applications, contributing to the development of effective and safe therapeutic options. This study presents the synthesis and characterization of sol-gel nanoparticles derived from Giloy (Tinospora cordifolia), a medicinal plant known for its diverse pharmacological properties. The sol-gel method offers a versatile approach for producing nanoparticles with controlled size and morphology. The synthesized Giloy sol-gel nanoparticles were characterized using various techniques such as scanning electron microscopy (SEM), transmission electron microscopy (TEM), X-ray diffraction (XRD), and Fourier-transform infrared spectroscopy (FTIR) to investigate their structural, morphological, and chemical properties. Furthermore, the potential biomedical applications of these nanoparticles, including their antimicrobial, antioxidant, and anti-inflammatory properties, were evaluated. The findings suggest that Giloy sol-gel nanoparticles hold promise for various biomedical applications, ranging from drug delivery systems to wound healing and tissue engineering. Further studies are warranted to explore their full therapeutic potential and optimize their formulation for clinical use.