Published Paper Details:

Pharmaceutical analysis plays an outstanding conspicuous role in quality assurance similarly to internal control of bulk medication and pharmaceutical formulations. As a consequence, analytical methodology development has become the essential activity of study. New drug molecules are being developed and the analysis is also gaining equal importance. A huge survey was conducted for the determination of antidiabetic drugs including Vildagliptin, Sitagliptin, Metformin etc. from the research articles published in various pharmaceutical and analytical chemistry Journals. Nowadays, many antidiabetic drugs are available in tablet dosage forms. The present article focuses on the different analytical methods for the quantitative estimation of antidiabetic drug. The present paper accentuates the review of analytical methods including UV/Vis-Spectroscopy, HPLC, RP-HPLC, HPTLC, GC-MS, LC-MS etc. which involve the estimation of antidiabetic drug in pharmaceutical dosage form. The investigatory review may provide comprehensive details of various analytical techniques and their experimental condition to the researchers who are working in the area of analytical research of antidiabetic drugs. The present studies revealed that the gas chromatographic method combined with mass spectroscopy has specific advantages and sensitivity for antidiabetic drug analysis in pharmaceutical dosage form and biological matrices.