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Background The Trigonella foenum-graecum plant is also known as methi and used in Ayurvedic medicines for the treatment of bronchitis, rheumatoid arthritis, abscesses and digestive abnormalities. The review article has been made for the standardization and phytochemical evaluation of Fenugreek seeds and this one is comprises of powder microscopy, fluorescence analysis. In modern food technology Fenugreek is used as food stabilizer, adhesive and emulsifying factor because of its gum, protein and fiber content. It is a rich source of calcium, iron and other vitamins. In this study after a general discussion of physio-chemical constituents, the biological and pharmacological reactions of Fenugreek. And to investigate the anti- inflammatory activity of suitable gel formulation. Method The polyherbal gel formulation was designed by using Carbopol 934, Sodium CMC, Trigonella foenum-graecum, Fenugreek extract, Ethanol, propylene glycol 400, methyl paraben, propyl paraben, and required amount of distilled water. The skin pH (6.8-7) was maintained by drop wise addition of tri- ethanolamine. The prepared polyherbal gels were evaluated for physical appearance, pH, spreadability, skin irritation to observe side effect. It was inferred from the results that polyherbal gel formulations were good in appearance and homogeneity. The overall result of this research the prepared poly herbal gel formulation shows significant anti-inflammatory activity. Results Gels were prepared using carbopol-934, HPMC K4M individually as well as in combination as gelling agents. Prepared formulations were evaluated for various physicochemical properties. The topical gel prepared from mixture carbopol-934 and HPMC K4M will be better gelling agent for making an ideal topical preparation. F1 batch shows the good results than other batches so F1 batch is suitable for anti- inflammatory use. The prepared formulation was evaluated various parameters. All of the evaluation tests were passed by the formulation. Conclusion Fenugreek has high potential as an anti-inflammatory agent when formulated as an herbal gel for topical use and can be effective in acute inflammatory disorders. The main purpose of this study was to formulate a stable and functionally effective anti- inflammatory gel with addition herbs with synthetic chemicals. The present study showed that the fenugreek gel possesses higher anti-inflammatory properties when compared with standard diclofenac sodium/Ibuprofen.