Published Paper Details:

Abstract Niosomes, which consist of vesicles formed by a combination of non-ionic surfactant and cholesterol, are a subject of interest. These structures are capable of serving as carriers for drugs that possess both hydrophilic and lipophilic properties. Within the realm of drug delivery systems, niosomes represent a method by which pharmaceuticals can be enclosed within vesicles. The appealing characteristics of niosomes include their biodegradability, biocompatibility, lack of immunogenicity, and structural flexibility. The primary aim of this literature review is to shed light on the diverse therapeutic applications of niosomes in the treatment of various medical conditions. This review will explore multiple facets concerning niosomes, such as their preparation techniques, mechanisms of action, facilitation of drug permeation, utilization as permeation enhancers, diverse applications in disease management, assessment of toxicity, and approaches to mitigating toxicity through the utilization of surfactants.