Published Paper Details:

The objective of the present study was to prepare a topical film-forming gel for the treatment of acne containing Garlic, Ashwagandha and Turmeric extract, using a patient-friendly drug delivery method. The localized cure of disease of our body tissues requires that the pharmaceutical active ingredient to be maintained at the site of treatment for some period of time. Sweat, garments and actions are some of the problems that have limited the helpfulness and residence time of conventional topical formulations mainly used for treatment of acne. Common human skin disease is acne vulgaris which is characterized by areas of skin with seborrhea, comedones, nodules (large papules), and pimples and possibly scarring. Herbal formulations have been constantly growing and important in the world market. The present formulation deals with the preparation and development of the herbal film forming anti-acne gel containing hydroalcoholic extract of Garlic (Allium sativum L., Alliaceae), Ashwagandha (withania somnifera ) and Turmeric (Curcuma longa) extract which is known for its anti-oxidant, anti-microbial & anti-inflammatory property. Various formulation batches i.e. S1 to S4 were formulated & evaluated for different parameters like color, appearance, consistency, pH, spreadability, antimicrobial activity & in vitro drug release. The formulation S3 with maximum spreadability & antimicrobial activity was selected as the optimized formulation. Antimicrobial activity was compared with the marketed formulation.