Published Paper Details:

The purpose of the study was to create and assess a dental gel with clove oil as its main ingredient for the treatment of periodontitis. Clove oil is chosen for the treatment of periodontitis because of its broad range of antibacterial activity against several periodontal infections. Using carbopol 934 as a gelling agent, clove oil as a therapeutic agent, polyethylene glycol as a co-solvent, methyl and propyl parabens as preservatives, and the necessary amount of distilled water as a carrier, clove oil gel is created. Gingivitis and periodontitis are examples of inflammatory conditions that are generated by plaque and are usually referred to as periodontal disease. Gingivitis is a mild stage of disease that is characterized by swelling, minor bleeding, and redness of the gingival edge. It is brought on by an accumulation of supragingival plaque. A shift in the microbiota from a more Gram-negative to a more Gram-positive anaerobic flora is linked to gingivitis. The more advanced form of periodontal disease known as periodontitis causes the alveolar bone to resorb and the periodontal ligament that supports the tooth to separate. In order to create a dental gel that would help treat periodontal illnesses, clove oil was added. The gel's physicochemical characteristics, such as its drug content, spreadability, extrusion ability, and in vitro antibacterial activity, were then assessed.