Published Paper Details:

Hypothyroxinemia and strabismus is a serious problem for Bangladesh as well as in the world. For this reason blindness occur in the world. It is an avoidable cause of blindness and has a global prevalence, which ranges from 2% to 6%. Low level of thyroid hormone thyroxin called hypothyroxinaemia is responsible for it. In different studies and analysis, the role of thyroid hormones at different phases of brain and neural development and maturation occurs and it is important and draws our attention for the vulnerable periods. These periods occur during gestation and lactation when genetic (nature) environmental (nurture) factors, which include nutrients and chemical contaminants, interfere with maternal and offspring thyroid health. Iodine deficiency from inadequate alimentary habits is the most common cause of maternal and foetal thyroid dysfunction. In addition, selenium (a component of deiodinases), iron (a component of the prosthetic heme group associated to thyroperoxidase) and other micronutrients are required for an adequate life-long thyroid function, especially during development and adolescence. Moreover, environmental anti-thyroid contaminants are acquiring increased importance for interference of thyroid hormone synthesis, transport and metabolism. Besides these, some auto-immune thyroid diseases also interfere thyroid hormone metabolism and help to develop the complications of eyes.