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ABSTRACT Background: Kati Graha is a vedanapradhanavyadhi. Patient feels pain and stiffness in the lumbar region, which hampers the normal activities of the person. It is one of the Nanatmajavatavayudhi mentioned by Acharya Sharangadhara. Acharya Shodala and Bhavaprakasha have mentioned Katigraha, as that characterized by Ruja (pain) and Graha (restricted movements) in Kati Pradesh, Hence it is considered as a separate disease in the classical text GadaNigraha. Agnikarma has been given special place in surgery by Sushruta and itis believed that disease treated by agnikarma never reoccurs. Agnikarma is considered as a boon for Sthanikavata and KaphajaVyadhi's and is highly recommended in the management of pain in wide spectrum of disorders. OBJECTIVES OF THE STUDY: To assess the effect of Agnikarma by lohashalaka in katigraha STUDY DESIGN: In present study a median age male patient (32 years) was diagnosed with katigraha and be selected for Agnikurma with Lohashalaka at under points in binduakruti in 4 sitting at interval of seven days with Snehana by Sahacharaditailam for sthanikaabhyanga and Lakshadiguggulu as internal medication. RESULT: Subjective and objective criteria's were statistically analyzed before and after treatment by applying standard statistical method.Agnikarma was found to be highly significant in all Subjective and Objective parameters in the study. CONCLUSION: Agnikarma provided better relief in Katishoola (pain in lower back) Therapeutic Heat of Agnikarma increases the blood circulation locally and flushes away the Pain producing substance. Agnikarma does the action at the level of muscle fibres causing relaxation of muscles thereby improving range of movement. No adverse reaction of therapy was found during and after the treatment. It was concluded that agnikarma therapies with lohashalaka have a definite role in relieving pain and stiffness in katigraha.