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INTERNATIONAL JOURNAL OF CREATIVE RESEARCH THOUGHTS - IJCRT (IJCRT.ORG)
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ISSN Approved Journal No: 2320-2882 | Impact factor: 7.97 | ESTD Year: 2013
Call For Paper - Volume 12 | Issue 7 | Month- July 2024
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Paper Title
Development and Validation of a Novel and Simple Method to Determine Prazosin hydrochloride by UV Spectrophotometry
Authors
Mansi B. Kalyani, Somnath A. Patil, Suraj R. Chakre, Nikesh D. Mukane, Nikita G. Katke
Keywords
Prazosin hydrochloride, Development, methanol, UV-Visible Spectrophotometric method, Validation
Abstract
For the purpose of quantifying prazosin in active pharmaceutical components and tablet dose formulation, an affordable, straightforward, accurate, precise, and versatile UV spectrophotometric approach based on absorption ratio has been developed and verified in accordance with ICH requirements. In the current investigation, prazosin was estimated using the absorbance values at 243 nm. The analyses findings for linearity, accuracy, precision, LOD, and LOQ have all been statistically confirmed. With a correlation coefficient of 0.9988, the procedure was shown to be linear in the concentration range of 1-5 g/ml. The results for the validation parameters also showed that the suggested approach was determined to be appropriate, sensitive, repeatable, accurate, and exact. As a result, this technique is helpful for routine quality control analysis to estimate prazosin in pharmaceutical.
IJCRT's Publication Details
Unique Identification Number - IJCRT2403133
Paper ID - 252469
Page Number(s) - b77-b82
Pubished in - Volume 12 | Issue 3 | March 2024
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Publisher Name - IJCRT | www.ijcrt.org | ISSN : 2320-2882
E-ISSN Number - 2320-2882
Cite this article
Mansi B. Kalyani, Somnath A. Patil, Suraj R. Chakre, Nikesh D. Mukane, Nikita G. Katke, "Development and Validation of a Novel and Simple Method to Determine Prazosin hydrochloride by UV Spectrophotometry", International Journal of Creative Research Thoughts (IJCRT), ISSN:2320-2882, Volume.12, Issue 3, pp.b77-b82, March 2024, Available at :http://www.ijcrt.org/papers/IJCRT2403133.pdf
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ISSN: 2320-2882 Impact Factor: 7.97 and ISSN APPROVED Journal Starting Year (ESTD) : 2013
ISSN and 7.97 Impact Factor Details
ISSN: 2320-2882 Impact Factor: 7.97 and ISSN APPROVED Journal Starting Year (ESTD) : 2013
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