Published Paper Details:

Plants provide valuable medicinal chemicals with significant potential in the pharmaceutical sector. The study aims to determine the phytochemical composition of therapeutic plants and evaluate their antioxidant and antibacterial properties. This study was undertaken with an objective of testing the antimicrobial and antioxidative properties of Alstonia Scholaris leaves and identifying the bioactive compound . Alstonia scholaris R. Br, a part of the Apocynaceae family, is a plant utilised in conventional medicine. The research aims to qualitatively examine and compare the initial phytochemical components present in the Alstonia scholaris leaves. The qualitative Phytochemical screening indicates the existence of flavonoids, phenolic compounds, alkaloids, phenols, and tannins in the leaf extracts. Analysed the antibacterial and antioxidant activities of Alstonia scholaris leaf extracts in vitro. The antibacterial efficacy of extract of leaves was assessed using an alcoholic extract to ascertain the minimal inhibitory concentration (MIC) for both positive and negative pathogens: Staphylococcus aureus, Escherichia coli, using disk diffusion method. Methanolic extract from leaf of Alstonia scholaris showed potential antioxidant activity and antimicrobial activity. Plant extracts' antioxidant activity was assessed by FRAP. The plant extracts exhibited strong antioxidant action against FRAP. The Alstonia scholaris extracts exhibited notable antibacterial activity, with minimum inhibitory concentration (MIC) values ranging from 31.25 to 1000 ug/ml, and demonstrated bactericidal activity against all tested species. The analysed extracts of medicinal plants in our research have the potential to serve as antioxidants, antibacterial agents, and as sources for creating novel pharmaceuticals.