Published Paper Details:

In the analysis of its potential to prevent diabetes, the effects of petroleum ether, chloroform and methanol, fast blood glucose and blood biochemical analyzes in streptozotocin diabetic rats were investigated. Of all three extracts, oral administration of 500 mg/kg of methanol extract significantly reduced glucose overload and streptozotocin in normal, normal rats after 15 days of treatment. Petroleum ether and chloroform extract did not show any significant effect on three groups of rats at an oral dose of 500 mg/kg. Simultaneous histological studies on the pancreas of these animals first demonstrated the comparative regenerative capacity of methanol extracts necrotic by streptozotocin. The results showed that it had a positive effect on diabetes in the experimental diabetes model. The plant material were collected dried and extracted. Among these ethanolic extract of Mollugo oppositifolius linn,and hydro-alcoholic extract of Glinus oppositifolius linn, were taken for studies. Glinus oppositifolius linn was examined for its anti-inflammatory activity also. The in-vitro analysis of both extracts were carried out and compared with standard drug. After screening the anti- diabetic property was confirmed by in- vivo methods. Both the plant extracts found to have a moderate to high capacity to regulate the hyperglycemia and associated complications.