Published Paper Details:

ODTs have received ever increasing demand and the field has become a rapidly growing area in the pharmaceutical industry. Upon introduction into the mouth, these tablets dissolve or disintegrate in the mouth in the absence of additional water. This review articles focuses on all aspects taken into consideration regarding formulation, development, parameters, technologies used, role of superdisintegrants incorporated and the latest advancement in the improvement of aforementioned drug delivery system to increase the patient compliance. Orodispersible tablets are solid unit dosage form which when placed in the oral cavity swiftly disintergrates or dissolves without the need of water. FDT formulations have the advantage of both conventional tablet formulation and liquid dosage form. There are several technologies that are conventional or patented based on spray drying, cotton candy process, sublimation, melt granulation, direct compression freezes drying/lyophilization, phase transition process, mass extrusion, etc. Recent advances in novel drug delivery (NDDS) aims to enhance safety and efficacy of drug molecule by formulating a convenient dosage form for ease of administration and to achieve better patient compliance. The aim of this article is to review the ideal properties, significance, characteristics, choice of drug candidates, challenges in formulation, various technologies for preparation of ODTs, formulation aspect, super disintegrant employed and technologies developed for FDTs, along with various excipients, evaluation test, in this research area.