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RESEARCH ABSTRACT Menopause is the end of menstruation. Menopause is usually natural, but can be induced. Natural menopause usually occurs between the age of 45 to 55 years. The average age of menopause worldwide is 51 years but in India it is just 46.2 years. Women's reproductive and sexual health has a distinct difference compared to men's health. Disproportionately low representation and discrimination in research studies of women has been addressed in United States and other western nations. It has also been noted that women often visit the gynaecologist lately and take quite less interventions and precautions to face it. Hence it is necessary to assess the knowledge regarding menopausal symptoms and its management. Aim : to assess the knowledge regarding menopausal symptoms and its management among women in selected urban and rural areas of Kamrup, Assam. Method & Material : A non-experimental comparative research design was used to accomplish the objectives. Study was undertaken among 68 women in urban and 68 in rural in selected areas of Kamrup, Assam by using convenient sampling technique. Self-structured knowledge questionnaire on menopausal symptoms and its management was used was used to assess knowledge regarding menopausal symptoms and its management among women. Modified Health Belief model was used as conceptual framework. Results : in urban area, 37(54.5%) had adequate knowledge, 28(41.2%) had moderately adequate knowledge and 3(4.4%) had inadequate knowledge of menopausal symptoms and its management. In rural area, 39(57.4%) had moderately adequate knowledge, 17 (25%) had adequate knowledge and 12(17.6%) had inadequate knowledge of menopausal symptoms and its management. Conclusion : The study revealed that women in urban had adequate knowledge and the women in rural area had moderatedly adequate knowledge regarding menopausal symptoms and its management.