Published Paper Details:

The oral route is considered to most natural, uncomplicated, convenient and safe due to its ease of administration, patient acceptance, and cost-effective production process. Many technological developments have resulted in the creation of controlled drug delivery systems, which have the potential to transform medication distribution and offer a multitude of therapeutic advantages. These systems address the shortcomings of conventional drug delivery methods. among the most popular methods for gastro-retentive drugs delivery. Several approaches are currently being used to prolong the GRT, including gastr-retentive drug delivery systems (GRDDS), also known as hydrodynamically balanced systems (HBS), swelling and expanding systems, high-density systems, and other delayed gastric emptying devices. One dosage form that is showing promise is floating dosage forms. By combining the right ingredients and a gas-generating agent, floating dosage forms can be made into tablets or capsules. This review on gastro-retentive drug delivery systems (GRDDS) was written with the intention of gathering the most recent research, paying particular attention to the main mechanism of floatation to accomplish gastric retention. The current study aims to improve bioavailability by extending the gastrointestinal residence duration by the creation of a gastro retentive floating bilayered tablet. A simple UV spectro photometric method has been employed for the estimation of API at 238 nm with a Beer's range of 0-10?g/ml. Fourier transform Infrared spectroscopy confirmed the absence of any drug/polymer's interactions.