Published Paper Details:

A lot of scientific and technological advancement have been made in the drug delivery research. Floating film drug delivery system has emerged as an advanced alternative to traditional dosage form like tablets, capsules and liquids. Floating film is drug loaded polymeric film mainly comprised of active pharmaceutical ingredients, polymers, film forming agent and plasticizer with the suitable solvent. Gastroretentive floating films are mainly made by using solvent evaporation and solvent casting methods. Present article gives emphasis on general consideration of gastroretentive floating films drug delivery system, with their advantages, disadvantages, method of preparation, evaluation parameters likes percent moisture absorbtion, folding endurance, tensile strength, drug content, dissolution study, release kinetic study, swelling index, in vitro buoyancy study and its applications. Layer-by-layer film technique will become a alternative for multidrug therapy in which controlled or sustained delivery of drug is possible by using different polymers. Multilayer approach will gain more importance in associated diseases like hypertension and diabetes etc.